Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Geoffrey, Talmon"'
Autor:
Thomas Auen, Geoffrey Talmon
Publikováno v:
Case Reports in Pathology, Vol 2024 (2024)
Nasopharyngeal carcinoma is an endemic entity with a strong association with Epstein-Barr virus and a new recognition of human papilloma virus-mediated effects in nonendemic areas. Here, we discuss a nasopharyngeal carcinoma suspected as based on ima
Externí odkaz:
https://doaj.org/article/f138c76ff55e4ae5b33c11d71aac50fa
Autor:
Staci L. Haney, Michelle L. Varney, Jacob T. Williams, Lynette M. Smith, Geoffrey Talmon, Sarah A. Holstein
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Background Multiple myeloma (MM) remains an incurable malignancy, despite the advent of therapies such as proteosome inhibitors (PIs) that disrupt protein homeostasis and induce ER stress. We have pursued inhibition of geranylgeranyl diphosp
Externí odkaz:
https://doaj.org/article/1de658b7b5734f53ac2c8d0362bbbce0
Autor:
Sienna Athy BA, Geoffrey Talmon MD, MEd, Kaeli Samson MA, MPH, Kimberly Martin CTAGME, Kari Nelson PhD, MA
Publikováno v:
Academic Pathology, Vol 8 (2021)
Competent physicians must be able to self-assess skill level; however, previous studies suggest that medical trainees may not accurately self-assess. We utilized Pathology Milestones (PM) data to determine whether there were discrepancies in self- ve
Externí odkaz:
https://doaj.org/article/27156a3b91a3421aa7afba2ff68df435
Autor:
Kishor K. Bhakat, Geoffrey Talmon, Vimla Band, Jing Wang, Kayvon Dowlatshahi, Sutapa Ray, Bhopal Mohapatra, Pranjal Biswas, Shrabasti Roychoudhury, Jiping Zeng, Heyu Song
Fluorouracil (5-FU) remains a first-line chemotherapeutic agent for colorectal cancer. However, a subset of colorectal cancer patients who have defective mismatch-repair (dMMR) pathway show resistance to 5-FU. Here, we demonstrate that the efficacy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1843bf67d130859e00938e1ddd3021
https://doi.org/10.1158/1535-7163.c.6542323
https://doi.org/10.1158/1535-7163.c.6542323
Autor:
Kishor K. Bhakat, Geoffrey Talmon, Vimla Band, Jing Wang, Kayvon Dowlatshahi, Sutapa Ray, Bhopal Mohapatra, Pranjal Biswas, Shrabasti Roychoudhury, Jiping Zeng, Heyu Song
Figure S1. IC50 decreased after APE1 knockdown. Figure S2. MMS increased colocalization of APE1 and FACT complex. Figure S3. FACT knockdown did not affect total APE1 level but decreased the occupancy of APE1 to p21 and DTL promoters. Figure S4. CBL01
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd119a27cebb62635e8405ddebb4e70
https://doi.org/10.1158/1535-7163.22519156
https://doi.org/10.1158/1535-7163.22519156
TGFbeta1 regulated genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228aba1259ab72b8c6c396fc98b10dae
https://doi.org/10.1158/0008-5472.22416267
https://doi.org/10.1158/0008-5472.22416267
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0478f177b07aec3ef0685b3d8f5d9bea
https://doi.org/10.1158/0008-5472.22416279.v1
https://doi.org/10.1158/0008-5472.22416279.v1
Leucine-rich repeat containing G-protein–coupled receptor 5 (LGR5), an intestinal stem cell marker, is known to exhibit tumor suppressor activity in colon cancer, the mechanism of which is not understood. Here we show that R-spondin 1 (RSPO1)/LGR5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11816443e3f407e8aff06a744ffd3afd
https://doi.org/10.1158/0008-5472.c.6509511
https://doi.org/10.1158/0008-5472.c.6509511
Fig. S1: Validation of colon cancer cell lines, LGR5 mRNA expression in normal colon, adenomas and carcinomas and evaluation of the specificity of the anti-LGR5 antibody in IHC Staining. Fig. S2: Primary tumor weight of CBS control and LGR5 knockdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4ce74d071ae3f0c00ed3d78ad6d46a
https://doi.org/10.1158/0008-5472.22416276
https://doi.org/10.1158/0008-5472.22416276
Autor:
Jirong (Betty) Mass, Geoffrey Talmon
Publikováno v:
Case Reports in Pathology, Vol 2018 (2018)
Undifferentiated pleomorphic sarcoma (UPS), previously known as malignant fibrous histiocytoma (MFH), is rarely reported in the liver as a primary site. We report a case of a previously healthy 56-year-old male, who presented with abdominal pain and
Externí odkaz:
https://doaj.org/article/da3cfd4198f941f3a107d7380848259d