Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Geoffrey, Farrell"'
Autor:
Jessie Qiaoyi Liang, Narcissus Teoh, Lixia Xu, Sharon Pok, Xiangchun Li, Eagle S. H. Chu, Jonathan Chiu, Ling Dong, Evi Arfianti, W. Geoffrey Haigh, Matthew M. Yeh, George N. Ioannou, Joseph J. Y. Sung, Geoffrey Farrell, Jun Yu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nonalcoholic steatohepatitis (NASH) and dietary cholesterol are risk factors for hepatocellular carcinoma (HCC). Here, the authors utilise mouse models to show that dietary cholesterol induces NASH by deregulating genes involved in metabolism, inflam
Externí odkaz:
https://doaj.org/article/f586a8b5cf4f4dbbb56141228ef1c3be
Autor:
Sun Woo Sophie Kang, Ghada Haydar, Caitlin Taniane, Geoffrey Farrell, Irwin M Arias, Jennifer Lippincott-Schwartz, Dong Fu
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165638 (2016)
Mitochondrial damage is the major factor underlying drug-induced liver disease but whether conditions that thwart mitochondrial injury can prevent or reverse drug-induced liver damage is unclear. A key molecule regulating mitochondria quality control
Externí odkaz:
https://doaj.org/article/3fb236c074764ca7865fd56349673cb7
Autor:
Hussam, Ajamieh, Geoffrey, Farrell, Heng Jian, Wong, Jun, Yu, Eagle, Chu, Jeffrey, Chen, Narci, Teoh
Publikováno v:
Journal of gastroenterology and hepatology. 27(8)
Steatosis accentuates the severity of hepatic ischemia-reperfusion injury (IRI). 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors ("statins") protect the heart and brain against post-ischemic injury, without necessarily lowering serum chole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5ab78c4e4fce6aaf5bfb6aadd881ae9
https://pubmed.ncbi.nlm.nih.gov/22823912
https://pubmed.ncbi.nlm.nih.gov/22823912
Autor:
Shivakumar, Chitturi, Geoffrey, Farrell, Linda, Frost, Adamandia, Kriketos, Rita, Lin, Caroline, Fung, Christopher, Liddle, Dev, Samarasinghe, Jacob, George
Publikováno v:
Hepatology (Baltimore, Md.). 36(2)
Nonalcoholic steatohepatitis (NASH) is a disorder characterized by hepatic steatosis, inflammation, and fibrosis. Leptin is an adipocyte-derived antiobesity hormone that in rodents prevents "lipotoxicity" by limiting triglyceride accumulation and als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11d05d2b5d3b179f64b1fafe9698072f
https://pubmed.ncbi.nlm.nih.gov/12143049
https://pubmed.ncbi.nlm.nih.gov/12143049
Publikováno v:
Hepatology (Baltimore, Md.). 36(1)
A brief period of hepatic ischemia protects the liver against subsequent ischemia-reperfusion (IR) injury, but the mechanism of such preconditioning is poorly understood. We examined whether preconditioning activated nuclear factor kappa B (NF-kappaB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a537a98205939506c15bd69c3216c2a4
https://pubmed.ncbi.nlm.nih.gov/12085353
https://pubmed.ncbi.nlm.nih.gov/12085353
Constitutive Activation of NF-B in Human Hepatocellular Carcinoma: Evidence of a Cytoprotective Role
Autor:
liang Qiao, Hongxia Zhang, Jun Yu, Rona Francisco, Paul Dent, Matthias P.A. Ebert, Christoph Rocke, Geoffrey Farrell
Publikováno v:
Human Gene Therapy. :060215071124002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3924ec2e431aee60fe03124179325d65
https://doi.org/10.1089/hum.2006.17.ft-184
https://doi.org/10.1089/hum.2006.17.ft-184
Autor:
Liang Qiao, Hongxia Zhang, Jun Yu, Rona Francisco, Paul Dent, Matthias P.A. Ebert, Christoph Röcken, Geoffrey Farrell
Publikováno v:
Human Gene Therapy; Mar2006, Vol. 17 Issue 3, p280-290, 11p