Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Geoffrey, Donnan"'
Autor:
Amy Brodtmann, Emilio Werden, Mohamed Salah Khlif, Laura J. Bird, Natalia Egorova, Michele Veldsman, Heath Pardoe, Graeme Jackson, Jennifer Bradshaw, David Darby, Toby Cumming, Leonid Churilov, Geoffrey Donnan
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Stroke survivors are at high risk of dementia, associated with increasing age and vascular burden and with pre-existing cognitive impairment, older age. Brain atrophy patterns are recognised as signatures of neurodegenerative conditions,
Externí odkaz:
https://doaj.org/article/9ac2877a745945ed803af3b3412190e5
Autor:
Hui Yin Lim, Brandon Lui, Mark Tacey, Anna Kwok, Suresh Varadarajan, Geoffrey Donnan, Harshal Nandurkar, Prahlad Ho
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 7, Pp n/a-n/a (2021)
Abstract Background There is significant heterogeneity in the incidence and severity of diabetes‐associated vascular complications and there is no routine biomarker that accurately predicts these outcomes. This pilot study investigates the role of
Externí odkaz:
https://doaj.org/article/2e7f05368ce845b79d5f884aa6003c95
Autor:
Hui Yin Lim, Brandon Lui, Mark Tacey, David Barit, Sheila K. Patel, Geoffrey Donnan, Harshal Nandurkar, Louise M. Burrell, Prahlad Ho
Publikováno v:
Thrombosis Research. 226:127-135
Autor:
Lan Gao, Mark Parsons, Leonid Churilov, Henry Zhao, Bruce CV Campbell, Bernard Yan, Peter Mitchell, Skye Coote, Francesca Langenberg, Karen Smith, David Anderson, Michael Stephenson, Stephen M Davis, Geoffrey Donnan, Damien Easton, Andrew Bivard
Publikováno v:
European Stroke Journal. 8:448-455
Background: Tenecteplase administered to patients with ischaemic stroke in a mobile stroke unit (MSU) has been shown to reduce the perfusion lesion volumes and result in ultra-early recovery. We now seek to assess the cost-effectiveness of tenectepla
Autor:
Peter Goodin, Gemma Lamp, Rishma Vidyasagar, Alan Connelly, Stephen Rose, Bruce C. V. Campbell, Tamara Tse, Henry Ma, David Howells, Graeme J. Hankey, Stephen Davis, Geoffrey Donnan, Leeanne M. Carey
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Background. One in three survivors of stroke experience poststroke depression (PSD). PSD has been linked with poorer recovery of function and cognition, yet our understanding of potential mechanisms is currently limited. Alterations in resting-state
Externí odkaz:
https://doaj.org/article/fc2c551c50694ac49beb955062ad19a4
Autor:
Felix C. Ng, Leonid Churilov, Nawaf Yassi, Timothy John Kleinig, Vincent Thijs, Teddy Wu, Darshan Shah, Helen Dewey, Gagan Sharma, Patricia Desmond, Bernard Yan, Mark Parsons, Geoffrey Donnan, Stephen Davis, Peter Mitchell, Bruce Campbell
Publikováno v:
Neurology. 98:e790-e801
Background and ObjectivesThe relevance of impaired microvascular tissue-level reperfusion despite complete upstream macrovascular angiographic reperfusion (no-reflow) in human stroke remains controversial. We investigated the prevalence and clinical-
Autor:
Christopher J. Renner, Scott E. Kasner, Philip M. Bath, Mona N. Bahouth, Kennedy R. Lees, Andrei Alexandrov, Erich Bluhmki, Natan Bornstein, Christopher Chen, Stephen M. Davis, Hans‐Christoph Diener, Geoffrey Donnan, Marc Fisher, Myron Ginsberg, Barbara Gregson, James Grotta, Werner Hacke, Michael G. Hennerici, Marc Hommel, Markku Kaste, Patrick Lyden, John Marler, Keith Muir, Christine Roffe, Ralph Sacco, Ashfaq Shuaib, Philip Teal, Narayanaswamy Venketasubramanian, Nils G. Wahlgren, Steven Warach, Christian Weimar
Publikováno v:
Journal of the American Heart Association. 11
Background We hypothesized that stroke outcome is related to multiple baseline hydration‐related factors including volume contracted state (VCS) and diuretic use. Methods and Results We analyzed a prospective cohort of subjects with ischemic stroke
Autor:
Hui Yin Lim, Sheila K. Patel, Ping Huang, Mark Tacey, Kay Weng Choy, Julie Wang, Geoffrey Donnan, Harshal H. Nandurkar, Prahlad Ho, Louise M. Burrell
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 9; Pages: 1495
Angiotensin converting enzyme 2 (ACE2) is an endogenous negative regulator of the renin-angiotensin system, a key factor in the development of cardiovascular disease (CVD). ACE2 is also used by SARS-CoV-2 for host cell entry. Given that COVID-19 is a
Publikováno v:
International journal of stroke : official journal of the International Stroke Society. 17(9)
Autor:
Andrew Bivard, Carlos Garcia-Esperon, Leonid Churilov, Neil Spratt, Michelle Russell, Bruce CV Campbell, Philip Choi, Timothy Kleinig, Henry Ma, Hugh Markus, Carlos Molina, Chung Hsu, Chon-Haw Tsai, Atte Meretoja, Daniel Strbian, Kenneth Butcher, Teddy Wu, Stephen Davis, Geoffrey Donnan, Christopher Levi, Mark Parsons
Publikováno v:
International Journal of Stroke. :174749302311543
Rationale: Alteplase is the only approved thrombolytic agent for acute stroke. An alternative plasminogen activator, tenecteplase, has been previously shown to increase early biological effectiveness (reperfusion) resulting in early clinical recovery