Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Geoff Liu"'
Autor:
Thomas E. Stinchcombe, Xiaofei Wang, Robert C. Doebele, Leylah M. Drusbosky, David E. Gerber, Leora Horn, Erin M. Bertino, Geoff Liu, Liza C. Villaruz, D. Ross Camidge
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 165
Brigatinib, a second generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI), is central nervous system (CNS) penetrant and active against anaplastic lymphoma kinase (ALK) resistance mutations. We prospectively studied the activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd88b84a1253e0b12cf02f22d037657c
https://pubmed.ncbi.nlm.nih.gov/35085983
https://pubmed.ncbi.nlm.nih.gov/35085983
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 24:484-489
Within current oncology practice, several genomic applications are being used to inform treatment decisions with molecularly targeted therapies in breast, lung, colorectal, melanoma, and other cancers. This commentary introduces a conceptual framewor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de2b148d696945aabbefd15c6b6b3fe
https://doi.org/10.1158/1055-9965.epi-14-1086
https://doi.org/10.1158/1055-9965.epi-14-1086
Autor:
Maria Teresa Landi, Tongwu Zhang, Montserrat Garcia-Closas, Yohan Bossé, Jianxin Shi, Bin Zhu, Qing Lan, Nathaniel Rothman, Jiyeon Choi, Neil E. Caporaso, Wei Zhao, Chongyi Chen, Eytan Ruppin, Jennifer Rosenbaum, Dmitry Gordenin, Sai Yendamuri, Chris Amos, Paul Brennan, David C. Christiani, Geoff Liu, Bonnie Gould Rothberg, Matthew Schabath, Han Liang, Ludmil Alexandrov, David Wedge, Stephen Chanock
Publikováno v:
Cancer Research. 79:SY26-02
Globally, about 2 million people are diagnosed with lung cancer annually, making it the most common type of cancer in the world. In addition, lung cancer is the leading cause of cancer death among both men and women, accounting for ~25% of all cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7de2b836bd5eb6bf7a6c8b0165ac1b18
https://doi.org/10.1158/1538-7445.am2019-sy26-02
https://doi.org/10.1158/1538-7445.am2019-sy26-02
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 26:A24-A24
BRM polymorphisms lie with the promoter region of the anticancer gene and SWI/SNF catalytic subunit, Brahma (SMARCA2). These polymorphisms statistically correlate with loss of BRM expression in both cell lines and primary lung tumors and function as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c55bb15bd1cf49750fa1c0187624ff47
https://doi.org/10.1158/1538-7755.carisk16-a24
https://doi.org/10.1158/1538-7755.carisk16-a24
Publikováno v:
Cancer Research. 70:1590-1590
BRM is a catalytic subunit of the SWI/SNF chromatin remodeling complex, which regulates the expression and function of key cellular proteins and signal transduction pathways, many of which have anticancer functions. BRM is lost in 15-25% of many soli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23da7dc992f6181f50a72caa4aade9a0
https://doi.org/10.1158/1538-7445.am10-1590
https://doi.org/10.1158/1538-7445.am10-1590
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention; Mar2015, Vol. 24 Issue 3, p484-489, 6p