Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Geoff Harley"'
Autor:
Marina Katerelos, Kurt Gleich, Geoff Harley, Kim Loh, Jonathan S. Oakhill, Bruce E. Kemp, David P. de Souza, Vinod K. Narayana, Melinda T. Coughlan, Adrienne Laskowski, Naomi X.Y. Ling, Lisa Murray-Segal, Robert Brink, Mardiana Lee, David A. Power, Peter F. Mount
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116730- (2024)
Acute kidney injury (AKI) disrupts energy metabolism. Targeting metabolism through AMP-activated protein kinase (AMPK) may alleviate AKI. ATX-304, a pan-AMPK activator, was evaluated in C57Bl/6 mice and tubular epithelial cell (TEC) cultures. Mice re
Externí odkaz:
https://doaj.org/article/49bb1d8ce07747f89e0a801918a28713
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280792 (2023)
The anti-fibrotic effect of metformin has been widely demonstrated. Fibrosis in the kidney after injury is associated with reduced expression of genes involved in both fatty acid and glycolytic energy metabolism. We have previously reported that the
Externí odkaz:
https://doaj.org/article/89cc1fc7b51546e3914b7f8eeb3906c0
Autor:
Geoff Harley, Marina Katerelos, Kurt Gleich, David P. de Souza, Vinod K. Narayana, Bruce E. Kemp, David A. Power, Peter F. Mount
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113377- (2022)
Background: Acute kidney injury (AKI) is accompanied by dysregulation of cellular energy metabolism and accumulation of intracellular lipid. Phosphorylation of acetyl-CoA carboxylase (ACC) by AMP-activated protein kinase (AMPK) inhibits fatty acid sy
Externí odkaz:
https://doaj.org/article/8ccc8f7c627a4d348026ba99eb9e8ba0
Autor:
Scott A Fraser, Marina Katerelos, Adrienne Laskowski, Geoff Harley, Mitchell A. Sullivan, Kurt Gleich, Melinda T. Coughlan, David A. Power, Mardiana Lee, Peter F Mount
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Fatty acid oxidation is the major energy pathway used by the kidney, although glycolysis becomes more important in the low oxygen environment of the medulla. Fatty acid oxidation appears to be reduced in renal fibrosis, and drugs that reverse this im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca9cfe0cf130641d795bb3ce0f2cbdc
http://europepmc.org/articles/PMC7471692
http://europepmc.org/articles/PMC7471692
Autor:
Suet-wan Choy, Natasha Cook, Lawrence P. McMahon, Charlotte Gibson, Megan Sandiford, Matthew A Roberts, Geoff Harley, Darren Lee, John B. Whitlam, Momena Manzoor
Publikováno v:
Nephrology. 23:616-624
Aim The Kidney Disease Improving Global Outcomes (KDIGO) guideline recommends the incorporation of a new risk calculator that quantifies the end stage kidney disease (ESKD) risk based on a composite profile of risk factors in living kidney donor cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::397e682a8fd399bbef8a796747bb28ed
https://doi.org/10.1111/nep.13074
https://doi.org/10.1111/nep.13074
Autor:
Natasha Cook, Suet Wan Choy, John B. Whitlam, Geoff Harley, Momena Manzoor, Matthew A Roberts, Lawrence P. McMahon, Darren Lee
Publikováno v:
Transplant International. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8636f67d7d87f117b1dce9cdae77e860
Autor:
Darren, Lee, Momena, Manzoor, Geoff, Harley, John, Whitlam, Natasha, Cook, Suet-Wan, Choy, Megan, Sandiford, Charlotte, Gibson, Lawrence P, McMahon, Matthew A, Roberts
Publikováno v:
Nephrology (Carlton, Vic.). 23(7)
The Kidney Disease Improving Global Outcomes (KDIGO) guideline recommends the incorporation of a new risk calculator that quantifies the end-stage kidney disease (ESKD) risk based on a composite profile of risk factors in living kidney donor candidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a055118ced0b3968f720845e2c68161b
https://pubmed.ncbi.nlm.nih.gov/28544308
https://pubmed.ncbi.nlm.nih.gov/28544308
Autor:
Geoff Harley
Publikováno v:
Victoria University of Wellington Law Review. 33:755-792
This paper provides an account of the nature and development of tax law. The author argues that tax law touches human activities to the extent that it is an accurate predictor of human and corporate behaviour. The paper examines several prominent tax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fbfefe7039ab1c63801a96e1f40b9a6
https://doi.org/10.26686/vuwlr.v33i3-4.5826
https://doi.org/10.26686/vuwlr.v33i3-4.5826