Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Geoff E. Gymer"'
Autor:
Michael A. Tones, Paul A. Bradley, Graham L. Smith, Lee R. Roberts, Geoff E. Gymer, Katherine S. England, Fox David Nathan Abraham, Steven E. Heasley, Michelle Schmidt, Mark E. Bunnage, Yvette M. Fobian, Jerome Molette, David Fairman, Dack Kevin Neil
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6515-6518
A series of acidic triazoles with activity as soluble guanylate cyclase stimulators is described. Incorporation of the CF3 triazole improved the overall physicochemical and drug-like properties of the molecule and is exemplified by compound 25.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54aefeeb064c19cd276466bf3d396d04
https://doi.org/10.1016/j.bmcl.2011.08.071
https://doi.org/10.1016/j.bmcl.2011.08.071
