Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Genzou, Takemura"'
Autor:
Takatomo Watanabe, Hideshi Okada, Hiromitsu Kanamori, Nagisa Miyazaki, Akiko Tsujimoto, Chihiro Takada, Kodai Suzuki, Genki Naruse, Akihiro Yoshida, Takahide Nawa, Toshiki Tanaka, Masanori Kawasaki, Hiroyasu Ito, Shinji Ogura, Hiroyuki Okura, Takako Fujiwara, Hisayoshi Fujiwara, Genzou Takemura
Publikováno v:
ESC Heart Failure, Vol 7, Iss 2, Pp 493-502 (2020)
Abstract Aims Although distinct DNA methylation patterns have been reported, its localization and roles remain to be defined in heart failure. We investigated the cellular and subcellular localization of DNA methylation and its pathophysiological sig
Externí odkaz:
https://doaj.org/article/83259b13074545c28ceca80d29dbff1e
Autor:
Hideshi Okada, Genzou Takemura, Kodai Suzuki, Kazumasa Oda, Chihiro Takada, Yasuaki Hotta, Nagisa Miyazaki, Akiko Tsujimoto, Isamu Muraki, Yoshiaki Ando, Ryogen Zaikokuji, Atsumu Matsumoto, Hiroki Kitagaki, Yuto Tamaoki, Takahiro Usui, Tomoaki Doi, Takahiro Yoshida, Shozo Yoshida, Hiroaki Ushikoshi, Izumi Toyoda, Shinji Ogura
Publikováno v:
Critical Care, Vol 21, Iss 1, Pp 1-10 (2017)
Abstract Background Sugar-protein glycocalyx coats healthy endothelium, but its ultrastructure is not well described. Our aim was to determine the three-dimensional ultrastructure of capillary endothelial glycocalyx in the heart, kidney, and liver, w
Externí odkaz:
https://doaj.org/article/7ed9769e3ef245c7956a9cf51a3cccb6
Autor:
Toshiki Kuno, Syohei Imaeda, Yohei Asakawa, Hiroshi Nakamura, Genzou Takemura, Daisuke Asahara, Akira Kanamori, Tomoyuki Kabutoya, Yohei Numasawa
Publikováno v:
Case Reports in Cardiology, Vol 2017 (2017)
We report a case with 46-year-old man diagnosed with mitochondrial cardiomyopathy in the dilated phase of hypertrophic cardiomyopathy. Since cardiac magnetic resonance imaging, beta-methyl-p-I123-iodophenyl-pentadecanoic myocardial scintigraphy, and
Externí odkaz:
https://doaj.org/article/8098b8811b584778a1e5cfb23844cce5
Autor:
Shuying Xu, John M. Leong, Megumi Inomata, Pallavi Chandra, Jennifer A. Philips, Genzou Takemura, Simin Nikbin Meydani
Publikováno v:
Proceedings of the National Academy of Sciences. 117:33561-33569
Streptococcus pneumoniae is a leading cause of pneumonia and invasive disease, particularly, in the elderly. S. pneumoniae lung infection of aged mice is associated with high bacterial burdens and detrimental inflammatory responses. Macrophages can c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da278c9b81f7c38e59d9e1ffd02dc079
https://doi.org/10.1073/pnas.2015368117
https://doi.org/10.1073/pnas.2015368117
Autor:
Keiko Ohta-Ogo, Yasuo Sugano, Soshiro Ogata, Takafumi Nakayama, Takahiro Komori, Kazuo Eguchi, Kaoru Dohi, Tetsuro Yokokawa, Hiromitsu Kanamori, Shigeyuki Nishimura, Kazufumi Nakamura, Yoshihiko Ikeda, Kunihiro Nishimura, Genzou Takemura, Toshihisa Anzai, Michiaki Hiroe, Kinta Hatakeyama, Hatsue Ishibashi-Ueda, Kyoko Imanaka-Yoshida
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 86(7)
Dilated cardiomyopathy (DCM) associated with inflammation is diagnosed by endomyocardial biopsy; patients with this have a poorer prognosis than patients without inflammation. To date, standard diagnostic criteria have not been established.Methods an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922ad03c92cb54cb2cd9e98ab1829d8c
https://pubmed.ncbi.nlm.nih.gov/35264513
https://pubmed.ncbi.nlm.nih.gov/35264513
Autor:
Hideshi Okada, Shigeo Takashima, Ryogen Zaikokuji, Isamu Muraki, Nagisa Miyazaki, Hiroaki Ushikoshi, Shinji Ogura, Ayane Nishio, Shozo Yoshida, Noriaki Yamada, Hirotsugu Fukuda, Keisuke Kumada, Genzou Takemura, Hiroyuki Tomita, Ayumi Kuroda, Tomoaki Doi, Tetsuya Fukuta, Kodai Suzuki, Takahiro Yoshida, Takatomo Watanabe, Akio Suzuki, Hirohisa Yano, Chihiro Takada
Publikováno v:
British Journal of Pharmacology
Background and purpose Disruption of the endothelial glycocalyx is causally related to microvascular endothelial dysfunction, a characteristic of sepsis-induced acute respiratory distress syndrome (ARDS). Recombinant human thrombomodulin (rhTM) atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3654d424550ea223a3cdf6f8e253030e
http://europepmc.org/articles/PMC7429482
http://europepmc.org/articles/PMC7429482
Autor:
Shinji Ogura, Toshiki Tanaka, Takahide Nawa, Hiroyasu Ito, Takatomo Watanabe, Akiko Tsujimoto, Hiromitsu Kanamori, Hisayoshi Fujiwara, Genzou Takemura, Akihiro Yoshida, Masanori Kawasaki, Genki Naruse, Chihiro Takada, Takako Fujiwara, Hideshi Okada, Nagisa Miyazaki, Hiroyuki Okura, Kodai Suzuki
Publikováno v:
ESC Heart Failure, Vol 7, Iss 2, Pp 493-502 (2020)
ESC Heart Failure
ESC Heart Failure
Aims Although distinct DNA methylation patterns have been reported, its localization and roles remain to be defined in heart failure. We investigated the cellular and subcellular localization of DNA methylation and its pathophysiological significance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9fedbc10da0cb990c509063fcb788a
https://doaj.org/article/83259b13074545c28ceca80d29dbff1e
https://doaj.org/article/83259b13074545c28ceca80d29dbff1e
Autor:
Takatomo Watanabe, Yasuaki Hotta, Tomoya Nakano, Shinji Ogura, Genzou Takemura, Takako Fujiwara, Hisayoshi Fujiwara, Yoshihiko Saito, Kenji Onoue, Takanori Arimoto, Hideshi Okada, Nagisa Miyazaki, Akiko Tsujimoto, Yasuhiro Sakaguchi, Hiromitsu Kanamori, Chihiro Takada, Tetsu Watanabe
Publikováno v:
Journal of Cardiology Cases. 21:54-58
We encountered an unfamiliar finding during electron microscopic examination of an endomyocardial biopsy obtained from a 55-year-old woman suffering from heart failure due to dilated phase hypertrophic cardiomyopathy. Many cardiomyocytes contained la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1e4c293df9f2e0c61834d0c5647869
https://doi.org/10.1016/j.jccase.2019.09.012
https://doi.org/10.1016/j.jccase.2019.09.012
Autor:
Akira Kawamoto, Takao Kato, Tetsuo Shioi, Junji Okuda, Tsuneaki Kawashima, Yodo Tamaki, Shinichiro Niizuma, Yohei Tanada, Genzou Takemura, Michiko Narazaki, Tetsuya Matsuda, Takeshi Kimura
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117091 (2015)
BACKGROUND:Many methods have been used to assess mitochondrial function. Technetium-99m sestamibi ((99m)Tc-MIBI), a lipophilic cation, is rapidly incorporated into myocardial cells by diffusion and mainly localizes to the mitochondria. The purpose of
Externí odkaz:
https://doaj.org/article/92b4a912e0274c07af4eec3bce3bbed2
Autor:
Shin Watanabe, Takahiro Horie, Kazuya Nagao, Yasuhide Kuwabara, Osamu Baba, Hitoo Nishi, Naoya Sowa, Michiko Narazaki, Tetsuya Matsuda, Genzou Takemura, Hiromichi Wada, Koji Hasegawa, Takeshi Kimura, Koh Ono
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108201 (2014)
The mechanism of cardiac energy production against sustained pressure overload remains to be elucidated.We generated cardiac-specific kinase-dead (kd) calcium/calmodulin-dependent protein kinase kinase-β (CaMKKβ) transgenic (α-MHC CaMKKβkd TG) mi
Externí odkaz:
https://doaj.org/article/ecc13d2be7d642a299af22c245b5f04f