Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Gentzon Hall"'
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 738 (2024)
Interleukins are a family of 40 bioactive peptides that act through cell surface receptors to induce a variety of intracellular responses. While interleukins are most commonly associated with destructive, pro-inflammatory signaling in cells, some als
Externí odkaz:
https://doaj.org/article/39fe32ff8732477987cea433f8163ae5
Autor:
Linda Wang, Bayle Smith-Salzberg, Kevin EC Meyers, Dorey A. Glenn, Katherine R. Tuttle, Vimal K. Derebail, Tammy M. Brady, Keisha Gibson, Abigail R. Smith, Michelle M. O’Shaughnessy, Tarak Srivastava, Gentzon Hall, Jarcy Zee, Markus Bitzer, Christine B. Sethna
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Tobacco exposure has been recognized as a risk factor for cardiovascular disease (CVD) and progression of kidney disease. Patients with proteinuric glomerulopathies are at increased risk for cardiovascular morbidity and mortality.
Externí odkaz:
https://doaj.org/article/5abe55563fbc42c09f55acec204d5aac
Autor:
Sarah E. Nystrom, Guojie Li, Somenath Datta, Karen L. Soldano, Daniel Silas, Astrid Weins, Gentzon Hall, David B. Thomas, Opeyemi A. Olabisi
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
COVID-19 infection causes collapse of glomerular capillaries and loss of podocytes, culminating in a severe kidney disease called COVID-19–associated nephropathy (COVAN). The underlying mechanism of COVAN is unknown. We hypothesized that cytokines
Externí odkaz:
https://doaj.org/article/80314d153ef540f08012cd60a5808a21
Autor:
Brandon M. Lane, Megan Chryst-Stangl, Guanghong Wu, Mohamed Shalaby, Sherif El Desoky, Claire C. Middleton, Kinsie Huggins, Amika Sood, Alejandro Ochoa, Andrew F. Malone, Ricardo Vancini, Sara E. Miller, Gentzon Hall, So Young Kim, David N. Howell, Jameela A. Kari, Rasheed Gbadegesin
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
We performed next-generation sequencing in patients with familial steroid-sensitive nephrotic syndrome (SSNS) and identified a homozygous segregating variant (p.H310Y) in the gene encoding clavesin-1 (CLVS1) in a consanguineous family with 3 affected
Externí odkaz:
https://doaj.org/article/e471d6c0a2dc49eb9ee43cce30adda9e
Autor:
Gentzon Hall, Christina M. Wyatt
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Proteinuria is common in the setting of HIV infection, and may reflect comorbid kidney disease, treatment-related nephrotoxicity, and HIV-related glomerular diseases. The mechanisms of podocyte and tubulointerstial injury in HIV-associated nephropath
Externí odkaz:
https://doaj.org/article/bf996ff06d1a4c69921e96264aa338eb
Autor:
Jiafa Ren, Yuemei Xu, Xiaohan Lu, Liming Wang, Shintaro Ide, Gentzon Hall, Tomokazu Souma, Jamie R. Privratsky, Robert F. Spurney, Steven D. Crowley
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
The transcription factor Twist1 regulates several processes that could impact kidney disease progression, including epithelial cell differentiation and inflammatory cytokine induction. Podocytes are specialized epithelia that exhibit features of immu
Externí odkaz:
https://doaj.org/article/8375eaae370841e0a7cb33cd4c61f063
Autor:
Jennifer D. Varner, Megan Chryst-Stangl, Christopher Imokhuede Esezobor, Adaobi Solarin, Guanghong Wu, Brandon Lane, Gentzon Hall, Asiri Abeyagunawardena, Ayo Matory, Tracy E. Hunley, Jen Jar Lin, David Howell, Rasheed Gbadegesin
Publikováno v:
Frontiers in Pediatrics, Vol 6 (2018)
Background: Steroid-resistant nephrotic syndrome (SRNS) is a leading cause of end-stage kidney disease in children and young adults. Despite advances in genomic science that have led to the discovery of >50 monogenic causes of SRNS, there are no clea
Externí odkaz:
https://doaj.org/article/ccaf3334511c48a6a29f435240e84d60
Publikováno v:
Cells, Vol 9, Iss 1, p 44 (2019)
Over a decade ago, mutations in the gene encoding TRPC6 (transient receptor potential cation channel, subfamily C, member 6) were linked to development of familial forms of nephrosis. Since this discovery, TRPC6 has been implicated in the pathophysio
Externí odkaz:
https://doaj.org/article/a1c8d974c14044199229b8c7999affcf
Autor:
Jiafa Ren, Xiaohan Lu, Gentzon Hall, Jamie R. Privratsky, Matthew J. Robson, Randy D. Blakely, Steven D. Crowley
Publikováno v:
Am J Physiol Renal Physiol
Interleukin (IL)-1 receptor type 1 (IL-1R1) activation triggers a proinflammatory signaling cascade that can exacerbate kidney injury. However, the functions of podocyte IL-1R1 in glomerular disease remain unclear. To study the role of IL-1R1 signali
Autor:
Gentzon Hall, Jennie Lin
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 79(6)