Identification of a possible proteomic biomarker in Parkinson’s disease: discovery and replication in blood, brain and CSF

Autor: Winchester, L, Barber, I, Lawton, M, Ash, J, Liu, B, Evetts, S, Hopkins-Jones, L, Lewis, S, Bresener, C, Malpartida, AB, Williams, N, Gentlemen, S, Wade-Martins, R, Ryan, B, Nevado-Holgado, A, Hu, M, Ben-Shlomo, Y, Grosset, D, Lovestone, S

Publikováno v: Winchester, L, Barber, I, Lawton, M A, Ash, J, Liu, B, Evetts, S, Hopkins-Jones, L, Lewis, S, Bresner, C, Malpartida, A B, Williams, N, Gentlemen, S, Wade-Martins, R, Ryan, B, Holgado-Nevado, A, Hu, M, Ben-Shlomo, Y, Grosset, D & Lovestone, S 2022, ' Identification of a possible proteomic Biomarker in Parkinson’s Disease : Discovery and Replication in Blood, brain and CSF ', Brain Communications . https://doi.org/10.1093/braincomms/fcac343

Biomarkers to aid diagnosis and delineate progression of Parkinson’s Disease are vital for targeting treatment in the early phases of disease. Here, we aim to discover a multi-protein panel representative of Parkinson’s and make mechanistic infer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::873caa8f82a1bbbf6a8fddd0778fb621
https://doi.org/10.1093/braincomms/fcac343

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Identification of a possible proteomic biomarker in Parkinson's disease: discovery and replication in blood, brain and cerebrospinal fluid.

Autor: Winchester L; Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK., Barber I; Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK., Lawton M; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Ash J; Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK., Liu B; Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK., Evetts S; Oxford Parkinson's Disease Centre and Division of Neurology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Hopkins-Jones L; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, Wales, UK., Lewis S; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, Wales, UK., Bresner C; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, Wales, UK., Malpartida AB; Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Williams N; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, Wales, UK., Gentlemen S; Department of Brain Sciences, Imperial College London, London, UK., Wade-Martins R; Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Ryan B; Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Holgado-Nevado A; Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK., Hu M; Oxford Parkinson's Disease Centre and Division of Neurology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Ben-Shlomo Y; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Grosset D; Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK., Lovestone S; Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK.

Publikováno v: Brain communications [Brain Commun] 2022 Dec 28; Vol. 5 (1), pp. fcac343. Date of Electronic Publication: 2022 Dec 28 (Print Publication: 2023).