Single‐cell transcriptomics stratifies organoid models of metabolic dysfunction‐associated steatotic liver disease.

Autor: Hess, Anja, Gentile, Stefan D, Ben Saad, Amel, Rahman, Raza‐Ur, Habboub, Tim, Pratt, Daniel S, Mullen, Alan C

Publikováno v: EMBO Journal; 12/11/2023, Vol. 42 Issue 24, p1-25, 25p

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Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs.

Autor: Sun C; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA., Zhou C; Department of Population and Quantitative Health Sciences, Chan Medical School, University of Massachusetts, Worcester, Massachusetts USA., Daneshvar K; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ben Saad A; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA., Kratkiewicz AJ; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Toles BJ; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA., Arghiani N; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA., Hess A; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Chen JY; Department of Medicine, Liver Center, University of California, San Francisco, California, USA., Pondick JV; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., York SR; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Li W; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Moran SP; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Gentile SD; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute, Cambridge, Massachusetts, USA., Rahman RU; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA.; Broad Institute, Cambridge, Massachusetts, USA., Li Z; Department of Population and Quantitative Health Sciences, Chan Medical School, University of Massachusetts, Worcester, Massachusetts USA., Zhou P; Department of Population and Quantitative Health Sciences, Chan Medical School, University of Massachusetts, Worcester, Massachusetts USA., Sparks RP; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA., Habboub T; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kim BM; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Choi MY; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Affo S; Department of Liver, Digestive System, and Metabolism, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain., Schwabe RF; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA., Popov YV; Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA., Mullen AC; Department of Medicine, Division of Gastroenterology, Chan Medical School, University of Massachusetts, Worcester, Massachusetts, USA.; Broad Institute, Cambridge, Massachusetts, USA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2024 Apr 02. Date of Electronic Publication: 2024 Apr 02.