Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Genthon, Arthur"'
Autor:
Genthon, Arthur
Single-cell experiments revealed substantial variability in generation times, growth rates but also in birth and division sizes between genetically identical cells. Understanding how these fluctuations determine the fitness of the population, i.e. it
Externí odkaz:
http://arxiv.org/abs/2411.08512
The fuel-driven process of replication in living systems generates distributions of copied entities with varying degrees of copying accuracy. Here we introduce a thermodynamically consistent ensemble for investigating universal population features of
Externí odkaz:
http://arxiv.org/abs/2403.05665
Publikováno v:
PRX Life 1, 013014 (2023)
Cell lineage statistics is a powerful tool for inferring cellular parameters, such as division rate, death rate or the population growth rate. Yet, in practice such an analysis suffers from a basic problem: how should we treat incomplete lineages tha
Externí odkaz:
http://arxiv.org/abs/2305.05406
Autor:
Genthon, Arthur
Publikováno v:
J. R. Soc. Interface 19 (2022)
Solving population balance equations, we derive analytical steady-state cell size distributions for single-lineage experiments, such as the mother machine. These experiments are fundamentally different from batch cultures where populations of cells g
Externí odkaz:
http://arxiv.org/abs/2206.06146
Publikováno v:
J. Phys. A: Math. Theor. 55 (2022) 074001
We study the Stochastic Thermodynamics of cell growth and division using a theoretical framework based on branching processes with resetting. Cell division may be split into two sub-processes: branching, by which a given cell gives birth to an identi
Externí odkaz:
http://arxiv.org/abs/2110.15147
Autor:
Genthon, Arthur, Lacoste, David
Publikováno v:
Phys. Rev. Research 3, 023187 (2021)
We obtain general inequalities constraining the difference between the average of an arbitrary function of a phenotypic trait, which includes the fitness landscape of the trait itself, in the presence or in the absence of natural selection. These ine
Externí odkaz:
http://arxiv.org/abs/2012.02734
Autor:
Genthon, Arthur
Publikováno v:
Eur. Phys. J. H 2020
Interest in Brownian motion was shared by different communities: this phenomenon was first observed by the botanist Robert Brown in 1827, then theorised by physicists in the 1900s, and eventually modelled by mathematicians from the 1920s, while still
Externí odkaz:
http://arxiv.org/abs/2006.05399
Autor:
Genthon, Arthur, Lacoste, David
Publikováno v:
Sci Rep 10, 11889 (2020)
We construct a pathwise formulation of a growing population of cells, based on two different samplings of lineages within the population, namely the forward and backward samplings. We show that a general symmetry relation, called fluctuation relation
Externí odkaz:
http://arxiv.org/abs/2004.04470
Publikováno v:
Phys. Rev. E 99, 042413 (2019)
Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels are derived. One of these relations implies specific inequalities comparing the popu
Externí odkaz:
http://arxiv.org/abs/1901.06932
Publikováno v:
Journal of Chemical Physics; 10/14/2023, Vol. 159 Issue 14, p1-12, 12p
