Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Gentaro, Iribe"'
Autor:
Sayaka Oda, Kazuhiro Nishiyama, Yuka Furumoto, Yohei Yamaguchi, Akiyuki Nishimura, Xiaokang Tang, Yuri Kato, Takuro Numaga-Tomita, Toshiyuki Kaneko, Supachoke Mangmool, Takuya Kuroda, Reishin Okubo, Makoto Sanbo, Masumi Hirabayashi, Yoji Sato, Yasuaki Nakagawa, Koichiro Kuwahara, Ryu Nagata, Gentaro Iribe, Yasuo Mori, Motohiro Nishida
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Baroreflex control of cardiac contractility is essential to maintain cardiocirculatory homeostasis. Here, Oda et al show that α1 adrenoceptor-stimulated Zn2+ entry through TRPC6 channels boosts β adrenoceptor-dependent myocardial positive inotropy.
Externí odkaz:
https://doaj.org/article/e32d11cf533d41b3a910892e7315812a
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/1e87785c9def4b3884b3cb1e9261ef38
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Introduction: In ventricular myocytes, spontaneous release of calcium (Ca2+) from the sarcoplasmic reticulum via ryanodine receptors (“Ca2+ sparks”) is acutely increased by stretch, due to a stretch-induced increase of reactive oxygen species (RO
Externí odkaz:
https://doaj.org/article/fc1c2a7d08cd4719a1e0cea463ff6f5f
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Transmural differences in ventricular myocardium are maintained by electromechanical coupling and mechano-calcium/mechano-electric feedback. In the present study, we experimentally investigated the influence of preload on the force characteristics of
Externí odkaz:
https://doaj.org/article/17d73dca72ef4a9dbca7caff83542f89
Publikováno v:
The Journal of Physiology.
Autor:
Yohei Yamaguchi, Masayoshi Nishiyama, Hiroaki Kai, Toshiyuki Kaneko, Keiko Kaihara, Gentaro Iribe, Akira Takai, Keiji Naruse, Masatoshi Morimatsu
Publikováno v:
Biophysical Journal. 122:267
Cardiomyocytes are contractile cells that regulate heart contraction. Ca
Autor:
Sayaka, Oda, Kazuhiro, Nishiyama, Yuka, Furumoto, Yohei, Yamaguchi, Akiyuki, Nishimura, Xiaokang, Tang, Yuri, Kato, Takuro, Numaga-Tomita, Toshiyuki, Kaneko, Supachoke, Mangmool, Takuya, Kuroda, Reishin, Okubo, Makoto, Sanbo, Masumi, Hirabayashi, Yoji, Sato, Yasuaki, Nakagawa, Koichiro, Kuwahara, Ryu, Nagata, Gentaro, Iribe, Yasuo, Mori, Motohiro, Nishida
Publikováno v:
Nature communications. 13(1)
Baroreflex control of cardiac contraction (positive inotropy) through sympathetic nerve activation is important for cardiocirculatory homeostasis. Transient receptor potential canonical subfamily (TRPC) channels are responsible for α
Autor:
Gentaro Iribe, Chen Wang, Marei Omori, Jian Chen, Masahiro Sokabe, Ken Takahashi, Keiko Kaihara, Jing Wang, Mari Miyajima, Masatoshi Morimatsu, Keiji Naruse, Shogo Hayashi
Publikováno v:
Cell Calcium. 79:68-74
The application of mechanical stimuli to cells often induce increases in intracellular calcium, affecting the regulation of a variety of cell functions. Although the mechanism of mechanotransduction-induced calcium increases has not been fully resolv
Publikováno v:
Biophysical Journal. 120:67a-68a
Publikováno v:
Progress in Biophysics and Molecular Biology. 130:315-322
Mitochondria are an important source of reactive oxygen species (ROS). Although it has been reported that myocardial stretch increases cellular ROS production by activating nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2), referre