Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Genro Fujisawa"'
Autor:
Eiko Nakazawa, Shigeaki Muto, Yoshitaka Iwazu, Koji Okada, Shun Ishibashi, Eiji Kusano, Genro Fujisawa
Publikováno v:
Hypertension. 51:749-754
We examined whether and how peritubular capillary (PTC) loss in the renal cortex contributes to the development of deoxycorticosterone acetate (DOCA)/salt-induced tubulointerstitial fibrosis. Uninephrectomized rats provided with 0.9% NaCl/0.3% KCl dr
Autor:
Yoshitaka Iwazu, Yasushi Asano, Sumiko Honma, Mitsunobu Murata, Eiji Kusano, Kiyoko Uki, Genro Fujisawa, Yoshiaki Sato, Ichiro Yanaka
Publikováno v:
Clinical and Experimental Nephrology. 11:230-234
A 66-year-old woman was admitted to our hospital because of vomiting and appetite loss. For the 2 days prior to admission, she had a cold, which had developed into acute viral bronchitis on admission. Because laboratory data on admission showed hypon
Publikováno v:
Translational Research. 148:149-156
Mineralocorticoid receptor (MR) antagonist spironolactone (SPL) is an effective agent for prevention of cardiovascular injury. However, whether and how SPL ameliorates hepatic fibrosis in rats is unknown. Pig serum (PS) (0.5 mL, twice a week, ip) or
Autor:
Nobuya Fujita, Naoki Itabashi, Eiji Kusano, Koji Okada, Shun Ishibashi, Genro Fujisawa, Shigeaki Muto
Publikováno v:
Kidney International. 66:1493-1502
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. Background Glomerular and tubulointerstitial injury leads to chronic impairment of renal function, and thus, reversal of the injury may improve renal function and sur
Publikováno v:
Endocrinology. 142:3625-3631
The rapid (1-4 h) responses of epithelial target tissues to mineralocorticoids contrast with the days/weeks apparently required for responses in the cardiovascular system. The present study explores the time course and pattern of early events leading
Publikováno v:
Endocrine Journal. 42:509-516
We demonstrated the functional evaluation of adrenal incidentaloma in 8 patients who had no abnormal finding associated with Cushing's syndrome. Adrenal tumors were incidentally discovered by abdominal echogram in 5 patients and by computed tomograph
Autor:
Genro Fujisawa, Yuko Watanabe, Nobuhiro Sasaki, Mariko Kimura, Eiji Kobayashi, Kazuyuki Shimada, Takahiro Masuda, Takahisa Kobayashi, Takashi Murakami, Eiji Kusano, Mutsuko Nonaka-Sarukawa, Masami Shinohara, Yoshitaka Iwazu, Shigeaki Muto
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 302(9)
To examine whether and how heart ANG II influences the coordination between cardiomyocyte hypertrophy and coronary angiogenesis and contributes to the pathogenesis of diabetic cardiomyopathy, we used Spontaneously Diabetic Torii (SDT) rats treated wi
Publikováno v:
Kidney International. 46:237-244
Therapeutic efficacy of the non-peptide AVP antagonist OPC-31260 in cirrhotic rats. The present study was undertaken to determine whether a non-peptide arginine vasopressin (AVP) antagonist [5-dimethylamino-1-{4-(2-methylbenzoylamino)benzoyl}-2,3,4,5
Publikováno v:
Endocrine Journal. 41:37-43
We studied the changes in serum sodium (Na) and potassium (K) levels in seventeen patients in diabetic ketoacidosis and nine patients in non-ketotic hyperosmolar coma, who had marked hyperglycemia (707.4 +/- 75.6 mg/dl, mean +/- SEM) and dehydration.
Autor:
Yoshitaka Iwazu, Shin'ichi Takeda, Ichiro Hirahara, Shigeaki Muto, Genro Fujisawa, Eiji Kusano
Publikováno v:
Journal of hypertension. 29(12)
Objectives Excess mineralocorticoids such as deoxycorticosterone acetate (DOCA) together with salt are known to cause tubulointerstitial fibrosis, but the mechanisms underlying fibrosis progression are unclear. Therefore, we investigated the role of