Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Genpei Kuriya"'
Autor:
Yoshiro Horai, Toshimasa Shimizu, Akitomo Okadae, Junichi Tokumitsu, Toshiyuki Ikeoka, Genpei Kuriya, Nozomi Iwanaga, Yasumori Izumi, Tomoki Origuchi, Atsushi Kawakami
Publikováno v:
Modern Rheumatology; Jul2022, Vol. 32 Issue 4, p830-833, 4p
Autor:
Yoshiro Horai, Toshimasa Shimizu, Akitomo Okada, Junichi Tokumitsu, Toshiyuki Ikeoka, Genpei Kuriya, Nozomi Iwanaga, Yasumori Izumi, Tomoki Origuchi, Atsushi Kawakami
Publikováno v:
Modern rheumatology. 32(4)
Autor:
Takao Ando, Ayaka Sako, Norio Abiru, Ichiro Yasuhi, Hiroshi Yamashita, Toshiyuki Ikeoka, Genpei Kuriya, Atsushi Kawakami, Ichiro Horie
Publikováno v:
Internal Medicine
A 27-year-old woman with a history of gestational diabetes mellitus (GDM) developed type 1 diabetes mellitus (T1D) in the early postpartum period. Women with a history of GDM are at an increased risk of developing T1D, which is rarer than type 2 diab
Autor:
Norio Abiru, Liping Yu, Atsushi Kawakami, Masoud Akbari, Toshifumi Matsuyama, Masakazu Kobayashi, Hironori Yamasaki, Katsuyuki Yui, Genpei Kuriya, Satoru Akazawa, Ichiro Horie, Minoru Okita, Yuji Nagayama
Publikováno v:
Diabetologia. 58(11):2606-2614
Aims/hypothesis: Interferon regulatory factor (IRF)4 plays a critical role in lymphoid development and the regulation of immune responses. Genetic deletion of IRF4 has been shown to suppress autoimmune disease in several mouse models, but its role in
Autor:
Yoshiro Horai, Tomoki Origuchi, Nozomi Iwanaga, Junichi Tokumitsu, Toshiyuki Ikeoka, Genpei Kuriya, Yasumori Izumi F., Atsushi Kawakami
Publikováno v:
Modern Rheumatology; July 2020, Vol. 30 Issue 4, p703-707, 5p
Autor:
Hitoshi Sasaki, Hironori Yamasaki, Shoichi Akazawa, T. Uchida, C Kaneko-Koike, Eiji Kawasaki, Masakazu Kobayashi, Genpei Kuriya, Kan Nakamura, Tsuyoshi Satoh, Norio Abiru, A. Kawakami, Hiroaki Ida, Yuji Nagayama
Publikováno v:
Clinical and Experimental Immunology. 173:411-418
Summary Granzyme B (GzmB) and perforin are proteins, secreted mainly by natural killer cells and cytotoxic T lymphocytes that are largely responsible for the induction of apoptosis in target cells. Because type 1 diabetes results from the selective d
Autor:
Yuji Nagayama, Norio Abiru, Yoichiro Iwakura, Kan Nakamura, A. Kawakami, Masakazu Kobayashi, T. Uchida, Ichiro Horie, Liping Yu, Hitoshi Sasaki, Hironori Yamasaki, Tsuyoshi Satoh, Genpei Kuriya, Shoichi Akazawa, Eiji Kawasaki
Publikováno v:
Diabetologia. 56:1773-1780
T helper type (Th) 17 cells have been shown to play important roles in mouse models of several autoimmune diseases that have been classified as Th1 diseases. In the NOD mouse, the relevance of Th1 and Th17 is controversial, because single-cytokine-de
Autor:
Hironori Yamasaki, Nobuo Matsuura, Tsuyoshi Satoh, Genpei Kuriya, Hironaga Kuwahara, Kan Nakamura, Norio Abiru, Katsumi Eguchi, Masakazu Kobayashi, Yasuko Uchigata, Junnosuke Miura, Eiji Kawasaki
Publikováno v:
Diabetes/Metabolism Research and Reviews. 27:895-898
The aim of this study was to determine the prevalence and role of autoantibodies to zinc transporter 8 (ZnT8A) in three forms (fulminant, acute-onset, and slow-onset) of Japanese patients with type 1 diabetes.One-hundred and ninety-six new-onset pati
Autor:
Norio Abiru, Hongbo Zhou, Katsumi Eguchi, Masakazu Kobayashi, Masataka Mori, G S Eisenbarth, Yuji Nagayama, Liping Yu, Eiichi Araki, Kan Nakamura, Hideki Nakamura, Eiji Kawasaki, Genpei Kuriya, Seiichi Oyadomari, Hironori Yamasaki, Tsuyoshi Satoh
Publikováno v:
Apoptosis : an international journal on programmed cell death. 16(4):438-448
C/EBP homologous protein (CHOP) has been proposed as a key transcription factor for endoplasmic reticulum (ER) stress-mediated β-cell death induced by inflammatory cytokines in vitro. However, the contribution of CHOP induction to the pathogenesis o
Autor:
Nobuo Matsuura, Norio Abiru, Eiji Kawasaki, Junnosuke Miura, Hironori Yamasaki, Yasuko Uchigata, Genpei Kuriya, Hironaga Kuwahara, Katsumi Eguchi, Masakazu Kobayashi, Kan Nakamura, Tsuyoshi Satoh
Publikováno v:
Clinical Immunology. 138:146-153
The aim of this study was to evaluate the humoral autoreactivity to zinc transporter 8 (ZnT8) depending on the clinical phenotype of type 1 diabetes (T1D). ZnT8 autoantibodies (ZnT8A) were determined by radioimmunoassay using carboxy-terminal ZnT8 co