Zobrazeno 1 - 10
of 419
pro vyhledávání: '"Genomics and Evolutionary Biology"'
Palaeogenomes of Eurasian straight-tusked elephants challenge the current view of elephant evolution
Autor:
Meyer, Matthias, Palkopoulou, Eleftheria, Baleka, Sina, Stiller, Mathias, Penkman, Kirsty E.H., Alt, Kurt W., Ishida, Yasuko, Mania, Dietrich, Mallick, Swapan, Meijer, Tom, Meller, Harald, Nagel, Sarah, Nickel, Birgit, Ostritz, Sven, Rohland, Nadin, Schauer, Karol, Schüler, Tim, Roca, Alfred L., Reich, David, Shapiro, Beth, Hofreiter, Michael
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The straight-tusked elephants Palaeoloxodon spp. were widespread across Eurasia during the Pleistocene. Phylogenetic reconstructions using morphological traits have grouped them with Asian elephants (Elephas maximus), and many paleontologists place P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3f7c7dea417e3796dd72b2205867dc33
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/44013
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/44013
Autor:
Nicolas Altemose, Nudrat Noor, Emmanuelle Bitoun, Afidalina Tumian, Michael Imbeault, J Ross Chapman, A Radu Aricescu, Simon R Myers
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
PRDM9 binding localizes almost all meiotic recombination sites in humans and mice. However, most PRDM9-bound loci do not become recombination hotspots. To explore factors that affect binding and subsequent recombination outcomes, we mapped human PRDM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8a9d9bbfd2db64edaff22aebc567a6e7
https://doi.org/10.7554/elife.28383.038
https://doi.org/10.7554/elife.28383.038
Autor:
Paolo Mita, Jef D. Boeke
Publikováno v:
eLife
LINE-1/L1 retrotransposon sequences comprise 17% of the human genome. Among the many classes of mobile genetic elements, L1 is the only autonomous retrotransposon that still drives human genomic plasticity today. Through its co-evolution with the hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79343e8300f8df6bcfb9c897f95d5e0a
https://pubmed.ncbi.nlm.nih.gov/29309036
https://pubmed.ncbi.nlm.nih.gov/29309036
Autor:
Yoav Gilad, Michelle C Ward, Siming Zhao, Bryan J Pavlovic, Mohammad M. Karimi, Kaixuan Luo, Matthew Stephens
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Transposable elements (TEs) comprise almost half of primate genomes and their aberrant regulation can result in deleterious effects. In pluripotent stem cells, rapidly evolving KRAB-ZNF genes target TEs for silencing by H3K9me3. To investigate the ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d16227ab5fbe8464e714afac0555b5
https://doi.org/10.7554/elife.33084
https://doi.org/10.7554/elife.33084
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
We studied adaptive evolution of gene expression using long-term experimental evolution of Saccharomyces cerevisiae in ammonium-limited chemostats. We found repeated selection for non-synonymous variation in the DNA binding domain of the transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302005fe168398c5aefba7884a78a580
https://doi.org/10.7554/elife.32323
https://doi.org/10.7554/elife.32323
Autor:
Adam S. Lauring, Ryan E. Malosh, Emily T. Martin, Arnold S. Monto, Robert J. Woods, John T. McCrone
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
The evolutionary dynamics of influenza virus ultimately derive from processes that take place within and between infected individuals. Here we define influenza virus dynamics in human hosts through sequencing of 249 specimens from 200 individuals col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c562c796fb27a7a874d90b0ba487a90
https://elifesciences.org/articles/35962
https://elifesciences.org/articles/35962
Autor:
Paula Gonçalves, Dana A. Opulente, Xiaofan Zhou, Antonis Rokas, Carla Gonçalves, Xing-Xing Shen, Jacek Kominek, Maria José Leandro, Madalena Salema-Oom, Chris Todd Hittinger, Cletus P. Kurtzman, Jennifer H. Wisecaver, David Peris
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
eLife
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
eLife, Vol 7 (2018)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
eLife
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
eLife, Vol 7 (2018)
Fructophily is a rare trait that consists of the preference for fructose over other carbon sources. Here, we show that in a yeast lineage (the Wickerhamiella/Starmerella, W/S clade) comprised of fructophilic species thriving in the high-sugar floral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b7f6ca0f89cd17ca35234d1f02a019
Autor:
Tobias Warnecke, David Rueda, Peter Bou Dib, Marina Rudan, Sandra Sobočanec, Anita Krisko, Marina Musa, Matea Kanunnikau
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Self-splicing introns are mobile elements that have invaded a number of highly conserved genes in prokaryotic and organellar genomes. Here, we show that deletion of these selfish elements from the Saccharomyces cerevisiae mitochondrial genome is stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491b3d46257eb18b8e9a49c0580199d9
https://doi.org/10.7554/elife.35330
https://doi.org/10.7554/elife.35330
Autor:
Maxim Ivanov, Sebastian Marquardt, Joseph Paul Parker, Dorine Jeanne Mariëtte du Mee, Stephen Buratowski
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Most DNA in the genomes of higher organisms does not code for proteins. RNA Polymerase II (Pol II) transcribes non-coding DNA into long non-coding RNAs (lncRNAs), but biological roles of lncRNA are unclear. We find that mutations in the yeast lncRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de00c8c491c3eda7fea19685f8c6691
https://doi.org/10.7554/elife.31989
https://doi.org/10.7554/elife.31989
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Codon usage biases are found in all genomes and influence protein expression levels. The codon usage effect on protein expression was thought to be mainly due to its impact on translation. Here, we show that transcription termination is an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807dc42526f91c7894354ce1fb18cdf6
https://elifesciences.org/articles/33569
https://elifesciences.org/articles/33569