Zobrazeno 1 - 10
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pro vyhledávání: '"Genomic subgroup"'
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Autor:
Murat Gunel, Zeynep Erson-Omay, Ketu Mishra-Gorur, Renelle Pointdujour-Lim, Arushii Nadar, Robert K. Fulbright, Lan Jin, Tanyeri Barak, Shaurey Vetsa, Evan Gorelick, Benjamin L. Judson, Jennifer Moliterno, Mariam Aboian, Michael Alperovich, Declan McGuone, S. Bulent Omay, Nicholas Blondin, Kanat Yalcin, Trisha P Gupte, Stephanie Aguilera, Mark W. Youngblood
Publikováno v:
Journal of Neuro-Oncology. 154:237-246
As sphenoid wing meningiomas (SWMs) are associated with varying degrees of bony involvement, we sought to understand potential relationships between genomic subgroup and this feature. Patients treated at Yale-New Haven Hospital for SWM were reviewed.
Akademický článek
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Autor:
Arushii Nadar, Murat Gunel, Lan Jin, Declan McGuone, Stephanie Aguilera, Tanyeri Barak, Ketu Mishra-Gorur, Benjamin L. Judson, Nicholas Blondin, Kanat Yalcin, Zeynep Erson-Omay, Robert K. Fulbright, Michael Alperovich, Shaurey Vetsa, Jennifer Moliterno, Mark W. Youngblood, Renelle Pointdujour-Lim, Trisha P Gupte, Mariam Aboian, S. Bulent Omay
Publikováno v:
Neuro Oncol
OBJECTIVE As sphenoid wing meningiomas (SWMs) are associated with varying degrees of bony involvement, we sought to understand potential relationships between genomic subgroup and this feature. METHODS Patients treated at Yale-New Haven Hospital for
Autor:
Youngblood MW; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery.; 3Department of Genetics, and., Duran D; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery.; 4Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi., Montejo JD; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery.; 5Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Li C; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery.; 6Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.; 7The Third Xiangya Hospital, Central South University, Changsha, China., Omay SB; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Özduman K; 8Department of Neurosurgery, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Istanbul, Turkey., Sheth AH; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Zhao AY; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Tyrtova E; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Miyagishima DF; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery.; 3Department of Genetics, and., Fomchenko EI; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Hong CS; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Clark VE; 9Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts., Riche M; 10Department of Neurosurgery, Hôpital Universitaire Pitié-Salpêtrière, AP-HP & Sorbonne Université, Paris, France., Peyre M; 10Department of Neurosurgery, Hôpital Universitaire Pitié-Salpêtrière, AP-HP & Sorbonne Université, Paris, France., Boetto J; 10Department of Neurosurgery, Hôpital Universitaire Pitié-Salpêtrière, AP-HP & Sorbonne Université, Paris, France., Sohrabi S; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Koljaka S; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Baranoski JF; 11Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona., Knight J; 3Department of Genetics, and.; 12Yale Center for Genome Analysis, Yale University West Campus, Orange, Connecticut., Zhu H; 13Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China., Pamir MN; 8Department of Neurosurgery, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Istanbul, Turkey., Avşar T; 14Department of Medical Biology, BAU Faculty of Medicine, Istanbul, Turkey., Kilic T; 15Department of Neurosurgery, Bahcesehir University, School of Medicine, Istanbul, Turkey., Schramm J; 16University of Bonn Medical School, Bonn, Germany., Timmer M; 17Center for Neurosurgery, University Hospital of Cologne, Germany., Goldbrunner R; 17Center for Neurosurgery, University Hospital of Cologne, Germany., Gong Y; 13Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China., Bayri Y; 18Department of Neurosurgery, Marmara University School of Medicine, Istanbul, Turkey., Amankulor N; 19Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Hamilton RL; 19Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Bilguvar K; 3Department of Genetics, and.; 12Yale Center for Genome Analysis, Yale University West Campus, Orange, Connecticut., Tikhonova I; 12Yale Center for Genome Analysis, Yale University West Campus, Orange, Connecticut., Tomak PR; 2Department of Neurosurgery., Huttner A; 1Yale Program in Brain Tumor Research.; 20Department of Pathology, Yale School of Medicine, New Haven, Connecticut and., Simon M; 16University of Bonn Medical School, Bonn, Germany.; 21Department of Neurosurgery, Bethel Clinic, Bielefeld, Germany., Krischek B; 17Center for Neurosurgery, University Hospital of Cologne, Germany., Kalamarides M; 10Department of Neurosurgery, Hôpital Universitaire Pitié-Salpêtrière, AP-HP & Sorbonne Université, Paris, France., Erson-Omay EZ; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Moliterno J; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery., Günel M; 1Yale Program in Brain Tumor Research.; 2Department of Neurosurgery.; 3Department of Genetics, and.; 12Yale Center for Genome Analysis, Yale University West Campus, Orange, Connecticut.; 22Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut.
Publikováno v:
Journal of neurosurgery [J Neurosurg] 2019 Oct 25; Vol. 133 (5), pp. 1345-1354. Date of Electronic Publication: 2019 Oct 25 (Print Publication: 2020).
Autor:
Patrick Tomak, Murat Gunel, Maximilien Riche, Ye Gong, Christopher S. Hong, Turker Kilic, James R. Knight, Sadaf Sohrabi, Sarah Koljaka, Koray Özduman, E. Zeynep Erson-Omay, Yasar Bayri, Johannes Schramm, Jennifer Moliterno, Danielle F Miyagishima, Evgeniya Tyrtova, Roland Goldbrunner, Jacob F Baranoski, Daniel Duran, Anita Huttner, Victoria E. Clark, Hongda Zhu, Julien Boetto, Michel Kalamarides, Elena I Fomchenko, Nduka Amankulor, Amar H. Sheth, Mark W. Youngblood, M. Necmettin Pamir, Julio D Montejo, Timucin Avsar, Chang Li, Kaya Bilguvar, Marco Timmer, Ronald L. Hamilton, Amy Y Zhao, Matthieu Peyre, Boris Krischek, Matthias Simon, Sacit Bulent Omay, Irina Tikhonova
Publikováno v:
Journal of Neurosurgery
Journal of Neurosurgery, American Association of Neurological Surgeons, 2019, pp.1-10. ⟨10.3171/2019.8.JNS191266⟩
Journal of Neurosurgery, American Association of Neurological Surgeons, 2019, pp.1-10. ⟨10.3171/2019.8.JNS191266⟩
OBJECTIVERecent large-cohort sequencing studies have investigated the genomic landscape of meningiomas, identifying somatic coding alterations in NF2, SMARCB1, SMARCE1, TRAF7, KLF4, POLR2A, BAP1, and members of the PI3K and Hedgehog signaling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb98422f65784e565c0d203e3a6c3908
https://hal.umontpellier.fr/hal-02549269
https://hal.umontpellier.fr/hal-02549269
Autor:
Zeynep Erson-Omay, Evgeniya Tyrtova, Lan Jin, Trisha P Gupte, Daniel Duran, Chang Li, Nduka Amankulor, Matthieu Peyre, Amar H. Sheth, Murat Gunel, Julien Boetto, Julio D Montejo, Turker Kilic, Jennifer Moliterno, Kaya Bilguvar, Koray Özduman, Timucin Avsar, Matthew Pease, Danielle F Miyagishima, Mark W. Youngblood, M Necmettiin Pamir, Michel Kalamarides, Francesco Iacoangeli, Anita Huttner, Amy Y Zhao
Publikováno v:
Neuro Oncol
Up to 80% of meningiomas are classified as clinically low-grade, however, a subset of these ‘benign’ cases will ultimately recur and require additional treatment. The role of molecular subgroup in meningioma recurrence has not been thoroughly inv
Autor:
Michel Kalamarides, Matthieu Peyre, Evgeniya Tyrtova, Amy Y Zhao, Amar H. Sheth, Sacit Bulent Omay, Mark W. Youngblood, Murat Gunel, Julio D Montejo, E. Zeynep Erson-Omay, Julien Boetto, Chang Li, Daniel Duran, Jennifer Moliterno, Koray Özduman
Publikováno v:
Neuro Oncol
BACKGROUND Meningiomas can be classified into six genomic subgroups based on mutations in NF2, SMARCB1, KLF4, POLR2A, or activating variants in the PI3K or Hedgehog signaling pathways. Previous work has identified specific associations of driver even
Akademický článek
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