Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Genomic Methodologies: Genome-phenotype association"'
Autor:
Andrew G. McArthur, Sommer Chou, Finlay Maguire, Haley L. Zubyk, Gerard D. Wright, Arman Edalatmand, Kara K. Tsang, Robert G. Beiko
Publikováno v:
Microbial Genomics
Diagnosing antimicrobial resistance (AMR) in the clinic is based on empirical evidence and current gold standard laboratory phenotypic methods. Genotypic methods have the potential advantages of being faster and cheaper, and having improved mechanist
Autor:
Chandler, Roe, Marc, Stegger, Berit, Lilje, Thor Bech, Johannesen, Kim Lee, Ng, Raphael N, Sieber, Elizabeth, Driebe, David M, Engelthaler, Paal Skytt, Andersen
Publikováno v:
Microbial Genomics
Staphylococcus aureus is a colonizing opportunistic pathogen and a leading cause of bloodstream infection with high morbidity and mortality. S. aureus carriage frequency is reportedly between 20 and 40 % among healthy adults, with S. aureus colonizat
Autor:
Daniel J. Wilson, David H. Wyllie, Justine K. Rudkin, Naomi E. Allen, Jacob Armstrong, Anne Marie O’Connell, Derrick W. Crook
Publikováno v:
Microbial Genomics
UK Biobank is an international health resource enabling research into the genetic and lifestyle determinants of common diseases of middle and older age. It comprises 500,000 participants. Public Health England’s Second Generation Surveillance Syste
Autor:
Michèle Gourmelon, Tine Hald, Marie-Léone Vignaud, Nanna Sophia Mucha Munck, Sabrina Cadel-Six, Federica Palma, Solen Lozach, Laurent Guillier
Publikováno v:
Microbial Genomics
Guillier, L, Gourmelon, M, Lozach, S, Cadel-Six, S, Vignaud, M-L, Munck, N S M, Hald, T & Palma, F 2020, ' AB_SA: Accessory genes-Based Source Attribution – tracing the source of Salmonella enterica Typhimurium environmental strains ', Microbial genomics, vol. 6, no. 7, 000366 . https://doi.org/10.1099/mgen.0.000366
Microbial Genomics (2057-5858) (Microbiology Society), 2020-07, Vol. 6, N. 7, P. 10p.
Guillier, L, Gourmelon, M, Lozach, S, Cadel-Six, S, Vignaud, M-L, Munck, N S M, Hald, T & Palma, F 2020, ' AB_SA: Accessory genes-Based Source Attribution – tracing the source of Salmonella enterica Typhimurium environmental strains ', Microbial genomics, vol. 6, no. 7, 000366 . https://doi.org/10.1099/mgen.0.000366
Microbial Genomics (2057-5858) (Microbiology Society), 2020-07, Vol. 6, N. 7, P. 10p.
The partitioning of pathogenic strains isolated in environmental or human cases to their sources is challenging. The pathogens usually colonize multiple animal hosts, including livestock, which contaminate the food-production chain and the environmen
Autor:
Saund, Katie, Snitkin, Evan S.
Publikováno v:
Microbial Genomics
Bacterial genome-wide association studies (bGWAS) capture associations between genomic variation and phenotypic variation. Convergence based bGWAS methods identify genomic mutations that arise more often in the presence of phenotypic variation than i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c83a930b7352078bba3877f4c51aeff
https://doi.org/10.1101/2020.04.19.048421
https://doi.org/10.1101/2020.04.19.048421
Autor:
Amelia R L, Charbonneau, Emma, Taylor, Catriona J, Mitchell, Carl, Robinson, Amy K, Cain, James A, Leigh, Duncan J, Maskell, Andrew S, Waller
Publikováno v:
Microbial Genomics
The availability of next-generation sequencing techniques provides an unprecedented opportunity for the assignment of gene function. Streptococcus equi subspecies equi is the causative agent of strangles in horses, one of the most prevalent and impor
Publikováno v:
Microbial Genomics
While variant identification pipelines are becoming increasingly standardized, less attention has been paid to the pre-processing of variants prior to their use in bacterial genome-wide association studies (bGWAS). Three nuances of variant pre-proces
Autor:
B. Jesse Shapiro, Morteza M. Saber
Publikováno v:
Microbial Genomics
Genome-wide association studies (GWASs) have the potential to reveal the genetics of microbial phenotypes such as antibiotic resistance and virulence. Capitalizing on the growing wealth of bacterial sequence data, microbial GWAS methods aim to identi
Autor:
Yair Motro, Neil Woodford, Jody Phelan, Jim F. Huggett, Matthew J. Ellington, Denise M. O'Sullivan, Liam P. Shaw, Jacob Moran-Gilad, Taane G. Clark, Martin Cormican, Kathryn A. Harris, Ronan Doyle, Ernest Diez Benavente, Alex van Belkum, Sebastian Bruchmann, Richard A. Stabler, Lucy van Dorp, Sean D Aller, Thi Phuong Thuy Nguyen, Elaine McGrath, Andreu Coello Pelegrin
Publikováno v:
BioRxiv
Microbial Genomics
Microbial Genomics
BackgroundAntimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial susceptibility testing (AST). As the implementation costs and technical barriers fall,
Autor:
Siân V. Owen, Nicolas Wenner, Jay C. D. Hinton, Rocío Canals, Disa L. Hammarlöf, Carsten Kröger
Publikováno v:
Microbial Genomics
Integrated phage elements, known as prophages, are a pervasive feature of bacterial genomes. Prophages can enhance the fitness of their bacterial hosts by conferring beneficial functions, such as virulence, stress tolerance or phage resistance, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33c3d0030deb68e5aefc1064b2eed7f
https://doi.org/10.1101/787010
https://doi.org/10.1101/787010