Zobrazeno 1 - 10
of 1 325
pro vyhledávání: '"Genome-wide association studies (GWAS)"'
Autor:
Mahmoud Amiri Roudbar, Seyed Milad Vahedi, Jin Jin, Mina Jahangiri, Hossein Lanjanian, Danial Habibi, Sajedeh Masjoudi, Parisa Riahi, Sahand Tehrani Fateh, Farideh Neshati, Asiyeh Sadat Zahedi, Maryam Moazzam-Jazi, Leila Najd-Hassan-Bonab, Seyedeh Fatemeh Mousavi, Sara Asgarian, Maryam Zarkesh, Mohammad Reza Moghaddas, Albert Tenesa, Anoshirvan Kazemnejad, Hassan Vahidnezhad, Hakon Hakonarson, Fereidoun Azizi, Mehdi Hedayati, Maryam Sadat Daneshpour, Mahdi Akbarzadeh
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract This study aims to assess the effect of familial structures on the still-missing heritability estimate and prediction accuracy of Type 2 Diabetes (T2D) using pedigree estimated risk values (ERV) and genomic ERV. We used 11,818 individuals (T
Externí odkaz:
https://doaj.org/article/d1778760f30742c2868c53ce140b1d16
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 37, Iss 8, Pp 635-649 (2024)
Stem rust, caused by the biotrophic fungal pathogen Puccinia graminis f. sp. tritici (Pgt), is an important disease of wheat. However, the majority of Pgt virulence/avirulence loci and underlying genes remain uncharacterized due to the constraints of
Externí odkaz:
https://doaj.org/article/ace9c4bb912e446dba1e0b8eb58342f0
Autor:
Amit Kumar Mazumder, Rajbir Yadav, Manjeet Kumar, Prashanth Babu, Naresh Kumar, Sanjay Kumar Singh, Amolkumar U. Solanke, Shabir H. Wani, Adel I. Alalawy, Abdulrahman Alasmari, Kiran B. Gaikwad
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract To sustainably increase wheat yield to meet the growing world population’s food demand in the face of climate change, Conservation Agriculture (CA) is a promising approach. Still, there is a lack of genomic studies investigating the geneti
Externí odkaz:
https://doaj.org/article/72fa7e431cf8444096a127fd5dafb2ae
Autor:
Shahrzad Manavi Nameghi
Publikováno v:
Endocrine and Metabolic Science, Vol 16, Iss , Pp 100193- (2024)
The pathophysiology of Type 2 Diabetes (T2D) is intricate, involving three main processes that lead to elevated glucose levels. Insulin resistance hinders glucose utilization in muscles, adipose tissue, and the liver. Additionally, pancreatic dysfunc
Externí odkaz:
https://doaj.org/article/d2cb188547304539a8ca15e3ccb4f6a8
Publikováno v:
Journal of Animal Science and Technology, Vol 66, Iss 3, Pp 567-576 (2024)
Subclinical ketosis (SCK) is a prevalent metabolic disorder that occurs during the transition to lactation period. It is defined as a high blood concentration of ketone bodies (beta-hydroxybutyric acid f ≥ 1.2 mmol/L) within the first few weeks of
Externí odkaz:
https://doaj.org/article/2ebad3544b8a4056b575216a507fc96e
Autor:
Yixuan Wang, Jinghan Huang, Ting Fang Alvin Ang, Yibo Zhu, Qiushan Tao, Jesse Mez, Michael Alosco, Gerald V. Denis, Anna Belkina, Ashita Gurnani, Mark Ross, Bin Gong, Jingyan Han, Kathryn L. Lunetta, Thor D. Stein, Rhoda Au, Lindsay A. Farrer, Xiaoling Zhang, Wei Qiao Qiu
Publikováno v:
Exploration of Medicine, Vol 5, Iss 2, Pp 193-214 (2024)
Aim: Endothelial dysfunction has been associated with both cerebrovascular pathology and Alzheimer’s disease (AD). However, the connection between circulating endothelial cells and the risk of AD remains uncertain. The objective was to leverage dat
Externí odkaz:
https://doaj.org/article/b829aced01d54988bacbfd62f99688f9
Autor:
Ping Xu, Hao Li, Haiyuan Li, Ge Zhao, Shengjie Dai, Xiaoyu Cui, Zhenning Liu, Lei Shi, Xiaohua Wang
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 4, Pp 1134-1149 (2024)
Phosphorus (P) is essential for living plants, and P deficiency is one of the key factors limiting the yield in rapeseed production worldwide. As the most important organ for plants, root morphology traits (RMTs) play a key role in P absorption. To i
Externí odkaz:
https://doaj.org/article/1f9e98314cb54f8999cedf6a4565da2a
Publikováno v:
Addictive Behaviors Reports, Vol 20, Iss , Pp 100569- (2024)
Several genetic and epigenetic factors contribute to the elevated substance use disorder (SUD) relapse vulnerability, yet a comprehensive investigation into these factors is lacking. This review aims to delve into current literature to highlight key
Externí odkaz:
https://doaj.org/article/878d4a6b0e4f462993946a173b3956c4
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionUlcerative colitis (UC) and diabetic kidney disease (DKD) are chronic disorders with multifaceted pathogenesis, posing significant challenges in clinical management. While substantial efforts have been made to investigate the individual c
Externí odkaz:
https://doaj.org/article/f37be6d84c044d13a15279b0344d4e33
Autor:
Nilanjan Roy, Acramul Haque Kabir, Nourin Zahan, Shahba Tasmiya Mouna, Sakshar Chakravarty, Atif Hasan Rahman, Md. Shamsuzzoha Bayzid
Publikováno v:
Plant Direct, Vol 8, Iss 6, Pp n/a-n/a (2024)
Abstract Rice genetic diversity is regulated by multiple genes and is largely dependent on various environmental factors. Uncovering the genetic variations associated with the diversity in rice populations is the key to breed stable and high yielding
Externí odkaz:
https://doaj.org/article/89c5f4b5885c46848025d34dc6ba94c3