Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Genome-wide DNA methylation"'
Autor:
Leyan Li, Xiao Fei, Huan Wang, Sihai Chen, Xinbo Xu, Huajing Ke, Yanan Zhou, Yi Hu, Cong He, Chuan Xie, Nonghua Lu, Jianping Liu, Yin Zhu, Nianshuang Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Globally, gastric cancer (GC) ranks among the most prevalent forms of malignancy, posing a significant health burden. Epigenetic modifications, predominantly characterized by alterations in DNA methylation patterns, have been linked to a div
Externí odkaz:
https://doaj.org/article/28211d843fc248d8bce9c6f777218d4a
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
DNA methylation plays a key role in sex determination and differentiation in vertebrates. However, there are few studies on DNA methylation involved in chicken gonad development, and most focused on male hypermethylated regions (MHM). It is unclear w
Externí odkaz:
https://doaj.org/article/a3924e6dbdf245b98eb2acaa13add4d2
Autor:
Devki Patel, Joseph P. McElroy, Daniel Y. Weng, Kamel Sahar, Sarah A. Reisinger, Jo L. Freudenheim, Mark D. Wewers, Peter G. Shields, Min-Ae Song
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Lung cancer exhibits sex-biased molecular characteristics and epidemiological trends, suggesting a need for sex-specific approaches to understanding its etiology and treatment. DNA methylation alterations play critical roles in lung carcinog
Externí odkaz:
https://doaj.org/article/413d5151e0d44b7fb069738a4d0c5a80
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 282, Iss , Pp 116743- (2024)
Particulate matter with aerodynamic diameters ≤2.5 µm (PM2.5) is a major environmental risk factor for acute asthma exacerbation, and the underlying mechanism is not completely understood. Studies have indicated that DNA methylation is a potential
Externí odkaz:
https://doaj.org/article/bd84cf2011c047128b85f8db2d86dc23
Autor:
Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Marc-André Sirard, Eveline M. Ibeagha-Awemu
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-25 (2024)
Abstract Background DNA methylation has been documented to play vital roles in diseases and biological processes. In bovine, little is known about the regulatory roles of DNA methylation alterations on production and health traits, including mastitis
Externí odkaz:
https://doaj.org/article/771011387c3f49418029b7e956702d93
Autor:
Frank M. Mezzacappa, Frankie K. Smith, Weiwei Zhang, Andrew Gard, Fatmagul Kusku Cabuk, Ignancio Gonzalez-Gomez, Hector L. Monforte, Jiancong Liang, Omkar Singh, Martha M. Quezado, Kenneth D. Aldape, Murat Gokden, Julia A. Bridge, Jie Chen
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Intracranial mesenchymal tumor (IMT), FET::CREB fusion-positive is a provisional tumor type in the 2021 WHO classification of central nervous system tumors with limited information available. Herein, we describe five new IMT cases from four
Externí odkaz:
https://doaj.org/article/4be89ec877884ba4bbc5044654b11183
Autor:
Jihoon E. Joo, Khalid Mahmood, Romy Walker, Peter Georgeson, Ida Candiloro, Mark Clendenning, Julia Como, Sharelle Joseland, Susan Preston, Lise Graversen, Mathilda Wilding, Michael Field, Michelle Lemon, Janette Wakeling, Helen Marfan, Rachel Susman, Joanne Isbister, Emma Edwards, Michelle Bowman, Judy Kirk, Emilia Ip, Lynne McKay, Yoland Antill, John L. Hopper, Alex Boussioutas, Finlay A. Macrae, Alexander Dobrovic, Mark A. Jenkins, Christophe Rosty, Ingrid M. Winship, Daniel D. Buchanan
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Background MLH1 epimutation is characterised by constitutional monoallelic MLH1 promoter hypermethylation, which can cause colorectal cancer (CRC). Tumour molecular profiles of MLH1 epimutation CRCs were used to classify germline MLH1 promot
Externí odkaz:
https://doaj.org/article/205aa9e2d6d045aca7e0fc588c972c5c
Autor:
Mengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Xin Zhao, Marc-André Sirard, Eveline M. Ibeagha-Awemu
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 13, Iss 1, Pp 1-21 (2022)
Abstract Background Mastitis caused by different pathogens including Streptococcus uberis (S. uberis) is responsible for huge economic losses to the dairy industry. In order to investigate the potential genetic and epigenetic regulatory mechanisms of
Externí odkaz:
https://doaj.org/article/d5f62d623f484e34aec9d5b58dbff7c2
Publikováno v:
Environment International, Vol 179, Iss , Pp 108188- (2023)
The physiochemical properties of graphene oxide may be affected by sunlight irradiation. However, the underlying mechanisms that alter the properties and subsequent intergenerational effects are not sufficiently investigate. Epigenetics is an early s
Externí odkaz:
https://doaj.org/article/c3388c9ae6764c3a9b1568f87836e958
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.