Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Genome segmentation"'
Autor:
Claus Vogl, Mariia Karapetiants, Burçin Yıldırım, Hrönn Kjartansdóttir, Carolin Kosiol, Juraj Bergman, Michal Majka, Lynette Caitlin Mikula
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Background Genomes are inherently inhomogeneous, with features such as base composition, recombination, gene density, and gene expression varying along chromosomes. Evolutionary, biological, and biomedical analyses aim to quantify this varia
Externí odkaz:
https://doaj.org/article/759e2df80c7f47a1802716bafec74d45
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Transcriptional regulation is primarily mediated by the binding of factors to non-coding regions in DNA. Identification of these binding regions enhances understanding of tissue formation and potentially facilitates the developmen
Externí odkaz:
https://doaj.org/article/98c10a2ce4f84c268d60a0af3aafcf79
Akademický článek
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Autor:
Fearnhead, Paul, Sherlock, Chris
Publikováno v:
Journal of the Royal Statistical Society. Series B (Statistical Methodology), 2006 Jan 01. 68(5), 767-784.
Externí odkaz:
https://www.jstor.org/stable/3879274
Autor:
Mikula, Lynette Caitlin
Single nucleotide polymorphisms in samples of DNA sequences from one or multiple populations can be summarised as site frequency spectra. Since polymorphic sites are known to be predominantly biallelic, models for the evolution of allele frequencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::b8f9795f15fe575e15dcbb3c5a7a96c9
https://hdl.handle.net/10023/27841
https://hdl.handle.net/10023/27841
Autor:
Manjula Algama, Edward Tasker, Caitlin Williams, Adam C. Parslow, Robert J. Bryson-Richardson, Jonathan M. Keith
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Computational identification of non-coding RNAs (ncRNAs) is a challenging problem. We describe a genome-wide analysis using Bayesian segmentation to identify intronic elements highly conserved between three evolutionarily distant
Externí odkaz:
https://doaj.org/article/0136b7119bc04100b84b7e0af6c3ecdb
Autor:
Bingxin Lu, Hon Wai Leong
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 200-206 (2016)
Clusters of genes acquired by lateral gene transfer in microbial genomes, are broadly referred to as genomic islands (GIs). GIs often carry genes important for genome evolution and adaptation to niches, such as genes involved in pathogenesis and anti
Externí odkaz:
https://doaj.org/article/cc9e45afbd074079a3541398076556fc
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Jul . 112(29), 8887-8892.
Externí odkaz:
https://www.jstor.org/stable/26466081
Akademický článek
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Autor:
Lin An, Douglas R. Higgs, Belinda Giardine, James W. Taylor, Elisabeth F. Heuston, Mitchell J. Weiss, Shaun Mahony, Qiang Li, Yu Zhang, Cheryl A. Keller, Berthold Göttgens, Gerd A. Blobel, Jens Lichtenberg, Ross C. Hardison, David M. Bodine, Guanjue Xiang, Feng Yue, Jim R. Hughes
Publikováno v:
Iubmb Life
Members of the GATA family of transcription factors play key roles in the differentiation of specific cell lineages by regulating the expression of target genes. Three GATA factors play distinct roles in hematopoietic differentiation. In order to bet