Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Genome Update"'
Publikováno v:
Human Genomics
Human Genomics, Vol 5, Iss 5, Pp 485-496 (2011)
Human Genomics, Vol 5, Iss 5, Pp 485-496 (2011)
The sirtuin family of proteins is categorised as class III histone deacetylases that play complex and important roles in ageing-related pathological conditions such as cancer and the deregulation of metabolism. There are seven members in humans, divi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542b65b268bdbe0dbb8309cce94158c6
http://europepmc.org/articles/PMC3230576
http://europepmc.org/articles/PMC3230576
Publikováno v:
Human Genomics
Human Genomics, Vol 5, Iss 1, Pp 30-55 (2010)
Human Genomics, Vol 5, Iss 1, Pp 30-55 (2010)
Cytokines play a very important role in nearly all aspects of inflammation and immunity. The term 'interleukin' (IL) has been used to describe a group of cytokines with complex immunomodulatory functions -- including cell proliferation, maturation, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe1c3713371be355d1375cba8eb000a
http://europepmc.org/articles/PMC3390169
http://europepmc.org/articles/PMC3390169
Publikováno v:
Human Genomics
Human Genomics, Vol 4, Iss 5, Pp 345-352 (2010)
Human Genomics, Vol 4, Iss 5, Pp 345-352 (2010)
The forkhead box (FOX) proteins are transcription factors that play complex and important roles in processes from development and organogenesis to regulation of metabolism and the immune system. There are 50 FOX genes in the human genome and 44 in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfef2be111e77a919210f8f64a2ba80
http://europepmc.org/articles/PMC3500164
http://europepmc.org/articles/PMC3500164
Publikováno v:
Human Genomics
Human Genomics, Vol 3, Iss 1, Pp 87-97 (2008)
Human Genomics, Vol 3, Iss 1, Pp 87-97 (2008)
The olfactory receptor gene (OR) superfamily is the largest in the human genome. The superfamily contains 390 putatively functional genes and 465 pseudogenes arranged into 18 gene families and 300 subfamilies. Even members within the same subfamily a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0df9e5978dd26f0bb131bcc6be0cd41
http://europepmc.org/articles/PMC2752031
http://europepmc.org/articles/PMC2752031
Publikováno v:
Human Genomics, Vol 2, Iss 5, Pp 329-335 (2006)
Human Genomics
Human Genomics
The NAD(P)H:quinone acceptor oxidoreductase (NQO) gene family belongs to the flavoprotein clan and, in the human genome, consists of two genes (NQO1 and NQO2). These two genes encode cytosolic flavoenzymes that catalyse the beneficial two-electron re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5932379377fffd3aef4e5ec526c90579
http://www.humgenomics.com/content/2/5/329
http://www.humgenomics.com/content/2/5/329
Autor:
David R. Nelson
Publikováno v:
Human Genomics, Vol 2, Iss 3, Pp 196-201 (2005)
Human Genomics
Human Genomics
The current proliferation of mammalian genomes is creating a nomenclature issue caused by naming genes based on their best BLAST hit to a gene in another annotated genome. The rat genome is relying heavily on the mouse genome for nomenclature, but no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6e80351c4b347bfeb7a4e122772368
http://www.humgenomics.com/content/2/3/196
http://www.humgenomics.com/content/2/3/196
Autor:
Vasilis Vasiliou, Daniel W. Nebert
Publikováno v:
Human Genomics, Vol 2, Iss 2, Pp 138-143 (2005)
Human Genomics
Human Genomics
The aldehyde dehydrogenase (ALDH) gene superfamily encodes enzymes that are critical for certain life processes and detoxification via the NAD(P)+-dependent oxidation of numerous endogenous and exogenous aldehyde substrates, including pharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b6b06fd09dad7a51cf1346fe661b8a
http://www.humgenomics.com/content/2/2/138
http://www.humgenomics.com/content/2/2/138
Autor:
David R. Nelson
Publikováno v:
Human Genomics, Vol 2, Iss 1, Pp 70-74 (2005)
Human Genomics
Human Genomics
The rapid accumulation of mutation data has led to the creation of nearly 300 locus-specific mutation databases. These sites may contain a few dozen to almost 20,000 mutations for a given gene. Many of the mutations are uncharacterised and have no kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6bd62601e61b2c1a0e1b15dca8ce45
http://www.humgenomics.com/content/2/1/70
http://www.humgenomics.com/content/2/1/70
Publikováno v:
Human Genomics, Vol 1, Iss 5, Pp 381-388 (2004)
Human Genomics
Human Genomics
Why is agreement on one particular name for each gene important? As one genome after another becomes sequenced, it is imperative to consider the complexity of genes, genetic architecture, gene expression, gene-gene and gene-product interactions and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666206ddd799375599e67c0fbff969c0
http://www.humgenomics.com/content/1/5/381
http://www.humgenomics.com/content/1/5/381
Autor:
David R. Nelson
Publikováno v:
Human Genomics
Human Genomics, Vol 1, Iss 4, Pp 310-316 (2004)
Human Genomics, Vol 1, Iss 4, Pp 310-316 (2004)
Annotation of the human genome is inching forward. Seven human chromosomes have now been fully annotated, covering 17 per cent of the genome, and at least one chromosome has been re-annotated. The enormity of the task forces a dependence on automated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e98fffc7977e025f0e77cb91746024
http://europepmc.org/articles/PMC3525266
http://europepmc.org/articles/PMC3525266