Zobrazeno 1 - 10
of 2 197
pro vyhledávání: '"Genome Replication and Regulation of Viral Gene Expression"'
Publikováno v:
J Virol
Bromodomain-containing protein 4 (Brd4) is a member of the bromodomain and extraterminal domain (BET) family of proteins. Brd4 regulates human papillomavirus (HPV) transcription, genome replication, and segregation by binding to the E2 protein. The S
Autor:
Youquan Zhong, Chuanjian Wu, Zaichao Xu, Yan Teng, Li Zhao, Kaitao Zhao, Jingjing Wang, Wen Wang, Qiong Zhan, Chengliang Zhu, Xinwen Chen, Kaiwei Liang, Xiaoming Cheng, Yuchen Xia
Publikováno v:
J Virol
Hepatitis B virus (HBV) infection is a major health burden worldwide, and currently there is no cure. The persistence of HBV covalently closed circular DNA (cccDNA) is the major obstacle for antiviral trement. HBV core protein (HBc) has emerged as a
Publikováno v:
J Virol
Viral protein genome-linked (VPg) protein plays an essential role in protein-primed replication of plus-stranded RNA viruses. VPg is covalently linked to the 5′ end of the viral RNA genome via a phosphodiester bond typically at a conserved amino ac
Publikováno v:
J Virol
Herpes simplex virus 1 (HSV-1) encodes a family B DNA polymerase (Pol) capable of exonucleolytic proofreading whose functions have been extensively studied in the past. Early studies on the in vitro activity of purified Pol protein found that the enz
Autor:
Luis Adrián De Jesús-González, Selvin Noé Palacios-Rápalo, José Manuel Reyes-Ruiz, Juan Fidel Osuna-Ramos, Carlos Noe Farfán-Morales, Carlos Daniel Cordero-Rivera, Bulmaro Cisneros, Ana Lorena Gutiérrez-Escolano, Rosa María del Ángel
Publikováno v:
J Virol
Flaviviruses have a cytoplasmic replicative cycle, and crucial events, such as genome translation and replication, occur in the endoplasmic reticulum. However, some viral proteins, such as C, NS1, and NS5 from Zika virus (ZIKV) containing nuclear loc
Autor:
Jeffery A. Nurdin, Tomohiro Kotaki, Takahiro Kawagishi, Shintaro Sato, Moeko Yamasaki, Ryotaro Nouda, Shohei Minami, Yuta Kanai, Takeshi Kobayashi
Publikováno v:
J Virol
Rotavirus (RV), the most common cause of gastroenteritis in children, carries a high economic and health burden worldwide. RV encodes six structural proteins and six nonstructural proteins (NSPs) that play different roles in viral replication. NSP4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8073bb9378a81fd5ed7adfc28b11c8
https://europepmc.org/articles/PMC9888287/
https://europepmc.org/articles/PMC9888287/
Autor:
Adam Wedrychowski, Holly Anne Martin, Yijia Li, Sushama Telwatte, Gayatri Nikhila Kadiyala, Meghan Melberg, Behzad Etemad, Elizabeth Connick, Jeffrey M. Jacobson, David M. Margolis, Daniel Skiest, Paul Volberding, Frederick Hecht, Steven Deeks, Joseph K. Wong, Jonathan Z. Li, Steven A. Yukl
Publikováno v:
Journal of virology, vol 97, iss 1
J Virol
J Virol
Posttreatment controllers (PTCs) are rare HIV-infected individuals who can limit viral rebound after antiretroviral therapy interruption (ATI), but the mechanisms of this remain unclear. To investigate these mechanisms, we quantified various HIV RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa36ec8558bac4429575ecaf8fecdb4
https://escholarship.org/uc/item/9zv2x2rv
https://escholarship.org/uc/item/9zv2x2rv
Autor:
Holly Anne Martin, Gayatri Nikhila Kadiyala, Sushama Telwatte, Adam Wedrychowski, Tsui-Hua Chen, Sara Moron-Lopez, Doug Arneson, Rebecca Hoh, Steven Deeks, Joseph Wong, Steven A. Yukl
Publikováno v:
J Virol
Journal of virology, vol 96, iss 24
Journal of virology, vol 96, iss 24
Most of the HIV DNA in infected individuals is noninfectious because of deleterious mutations. However, it is unclear how much of the transcribed HIV RNA is potentially infectious or defective. To address this question, we developed and validated a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e8711fa9836d8f06b904e5e9f66c9b
https://europepmc.org/articles/PMC9769383/
https://europepmc.org/articles/PMC9769383/
Publikováno v:
J Virol
Herpesviral infection reflects thousands of years of coevolution and the constant struggle between virus and host for control of cellular gene expression. During Kaposi’s sarcoma-associated herpesvirus (KSHV) lytic replication, the virus rapidly se
Autor:
Cong Yuan, Xuepeng Suo, Yueyue Duan, Xiangtong Li, Lei Shi, Liyan Cao, Xiangyu Kong, Haixue Zheng, Qi Wang
Publikováno v:
J Virol
Bats are reservoirs for diverse coronaviruses, including swine acute diarrhea syndrome coronavirus (SADS-CoV). SADS-CoV was first identified in diarrheal piglets in 2017. As a novel alphacoronavirus, SADS-CoV shares ~95% identity with bat alphacorona