Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Gennaro de Libero"'
Autor:
Michela Consonni, Claudio Garavaglia, Andrea Grilli, Claudia de Lalla, Alessandra Mancino, Lucia Mori, Gennaro De Libero, Daniela Montagna, Monica Casucci, Marta Serafini, Chiara Bonini, Daniel Häussinger, Fabio Ciceri, Massimo Bernardi, Sara Mastaglio, Silvio Bicciato, Paolo Dellabona, Giulia Casorati
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Leukaemia therapy may benefit from the use of antigens that are less restricted to individual donors. Here the authors engineered T cells with a TCR specific for a CD1c restricted lipid leukaemia antigen and show that they can protect against disease
Externí odkaz:
https://doaj.org/article/a21e6ce293244d2e824f24fa9452ea8d
Autor:
Christina K. S. Muller, Julian Spagnuolo, Annette Audigé, Andrew Chancellor, Doris Russenberger, Alexandra U. Scherrer, Matthias Hoffmann, Roger Kouyos, Manuel Battegay, Gennaro De Libero, Roberto F. Speck, the Swiss HIV Cohort Study
Publikováno v:
Infectious Agents and Cancer, Vol 16, Iss 1, Pp 1-15 (2021)
Abstract Background Despite successful combined antiretroviral therapy (cART), the risk of non-AIDS defining cancers (NADCs) remains higher for HIV-infected individuals than the general population. The reason for this increase is highly disputed. Her
Externí odkaz:
https://doaj.org/article/1aebcb623b2c4582bc273362ad7f6b45
Autor:
Daniela Di Blasi, Tujana Boldanova, Lucia Mori, Luigi Terracciano, Markus H. Heim, Gennaro De Libero
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 195-218 (2020)
Background & Aims: The characterization of T cells infiltrating hepatocellular carcinoma (HCC) provides information on cancer immunity and also on selection of patients with precise indication of immunotherapy. The aim of the study was to characteriz
Externí odkaz:
https://doaj.org/article/cca427693c764d88bc91f9f60a02ef18
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Non-polymorphic MHC class I-related molecule MR1 presents antigenic bacterial metabolites to mucosal-associated invariant T (MAIT) cells and self-antigens to MR1-restricted T (MR1T) cells. Both MR1-restricted T cell populations are readily identified
Externí odkaz:
https://doaj.org/article/b0cce227525e48b2b36efaf64085dadf
Autor:
Frank Camacho, María E Sarmiento, Fatima Reyes, Louise Kim, Jim Huggett, Marco Lepore, Oscar Otero, Martine Gilleron, Germain Puzo, Mohd Nor Norazmi, Graham Rook, Lucia Mori, Gennaro De Libero, Armando Acosta
Publikováno v:
International Journal of Mycobacteriology, Vol 5, Iss 2, Pp 120-127 (2016)
Objective/background: The development of new tools capable of targeting Mycobacterium tuberculosis (Mtb)-infected cells have potential applications in diagnosis, treatment, and prevention of tuberculosis. In Mtb-infected cells, CD1b molecules present
Externí odkaz:
https://doaj.org/article/99975624cc9f4975a1db3f4d7cbb2f23
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The definition “unconventional T cells” identifies T lymphocytes that recognize non-peptide antigens presented by monomorphic antigen-presenting molecules. Two cell populations recognize lipid antigens and small metabolites presented by CD1 and M
Externí odkaz:
https://doaj.org/article/4dca8bcddeb24434b153dba3a94d0288
Autor:
Maurizio Vacca, Julia Böhme, Lia Paola Zambetti, Hanif Javanmard Khameneh, Bhairav S. Paleja, Federica Laudisi, Adrian W. S. Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Amit Singhal, Alessandra Mortellaro
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10−/− mouse to delineate the role of NLRP10 in the host immune re
Externí odkaz:
https://doaj.org/article/0d658a4472974b4ead4b0eed71d2a1e9
Autor:
Stefan H. E. Kaufmann, Hazel M. Dockrell, Nick Drager, Mei Mei Ho, Helen McShane, Olivier Neyrolles, Tom H. M. Ottenhoff, Brij Patel, Danielle Roordink, François Spertini, Steffen Stenger, Jelle Thole, Frank A. W. Verreck, Ann Williams, TBVAC2020 Consortium, Warwick Britton, Jamie Triccas, Claudio Counoupas, Johan Grooten, Marie-Ange Demoitie, Marta Romano, Francoise Mascart, Peter Andersen, Claus Aagaard, Dennis Christensen, Morten Ruhwald, Thomas Lindenstrom, Pierre Charneau, Christophe Guilhot, Antonio Peixoto, Martine Gilleron, Camille Locht, Roland Brosch, Genevieve Inchauspe, Stephane Leung Theung Long, Stefan Kaufmann, January Weiner, Jeroen Maertzdorf, Natalie Neuwenhuizen, Max Bastian, Nadia Caccamo, Delia Goletti, Roberto Nisini, Sung Jae Shin, Hyejon Lee, Alex Sigal, Thomas Scriba, Gerhard Walzl, Andre Loxton, Robert Wilkinson, Pere-Joan Cardona, Cris Vilaplana, Carlos Martin, Dessi Marinova, Nacho Aguilo, Ruedi Aebersold, Etienne Caron, Daniel Pinschewer, Gennaro De Libero, Claire Anne Siegrist, Nicolas Collin, Christophe Barnier-Quer, Peter Sander, Frank Verreck, Tom Ottenhoff, Simone Joosten, Krista van Meijgaarden, Mariateresa Coppola, Annemieke Geluk, Yvonne Perrie, Marc Baird, Michael Levin, Hazel Dockrell, Steven Smith, Helen Fletcher, Gregory Bancroft, Ann Rawkins, Simon Clark, Iman Satti, Elena Stylianou, Martin Vordermeier, Philip Hogarth
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
TBVAC2020 is a research project supported by the Horizon 2020 program of the European Commission (EC). It aims at the discovery and development of novel tuberculosis (TB) vaccines from preclinical research projects to early clinical assessment. The p
Externí odkaz:
https://doaj.org/article/c7965df9c6da40b7adb41882e3834949
Autor:
Marco Lepore, Artem Kalinichenko, Salvatore Calogero, Pavanish Kumar, Bhairav Paleja, Mathias Schmaler, Vipin Narang, Francesca Zolezzi, Michael Poidinger, Lucia Mori, Gennaro De Libero
Publikováno v:
eLife, Vol 6 (2017)
Externí odkaz:
https://doaj.org/article/3374ccea4ada4b3e9c91ab2953cb90b9
Autor:
Marco Lepore, Artem Kalinichenko, Salvatore Calogero, Pavanish Kumar, Bhairav Paleja, Mathias Schmaler, Vipin Narang, Francesca Zolezzi, Michael Poidinger, Lucia Mori, Gennaro De Libero
Publikováno v:
eLife, Vol 6 (2017)
MHC class I-related molecule MR1 presents riboflavin- and folate-related metabolites to mucosal-associated invariant T cells, but it is unknown whether MR1 can present alternative antigens to other T cell lineages. In healthy individuals we identifie
Externí odkaz:
https://doaj.org/article/ff20e9a13f644a6d899b550d0f9e97dd