Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Gennaro D'urso"'
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Gene networks in living cells can change depending on various conditions such as caused by different environments, tissue types, disease states, and development stages. Identifying the differential changes in gene networks is very
Externí odkaz:
https://doaj.org/article/89ea275f4a3446fab9402104d784deae
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Arginyltransferase1 (ATE1) is a conserved enzyme in eukaryotes mediating posttranslational arginylation, the addition of an extra arginine to an existing protein. In mammals, the dysregulations of the ATE1 gene (ate1) is shown to be involved in cardi
Externí odkaz:
https://doaj.org/article/a92c2ca32a5c4ec996335c65a6875578
Autor:
Fiorella Magani, Eric R Bray, Maria J Martinez, Ning Zhao, Valeria A Copello, Laine Heidman, Stephanie O Peacock, David J Wiley, Gennaro D'Urso, Kerry L Burnstein
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 8, Pp 1-15 (2018)
Abstract Identifying critical pathways governing disease progression is essential for accurate prognosis and effective therapy. We developed a broadly applicable and novel systems‐level gene discovery strategy. This approach focused on constitutive
Externí odkaz:
https://doaj.org/article/e1b727fc25104d4baa5a654efb317164
Autor:
Chris D. Balak, Jesse M. Hunter, Mary E. Ahearn, David Wiley, Gennaro D'urso, Lisa Baumbach-Reardon
Publikováno v:
F1000Research, Vol 6 (2017)
Background: X-linked spinal muscular atrophy (XL-SMA) results from mutations in the Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1). Previously, four novel closely clustered mutations have been shown to cause this fatal infantile disorder affectin
Externí odkaz:
https://doaj.org/article/78eeee3cbf8245818e7a911b5e49f9de
Autor:
David J. Wiley, Ilona Juan, Hao Le, Xiaodong Cai, Lisa Baumbach, Christine Beattie, Gennaro D'Urso
Publikováno v:
F1000Research, Vol 3 (2014)
Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets. Here we introduce our Yeast Augmented Network Analysis
Externí odkaz:
https://doaj.org/article/593dfbbc94c5478fa467eeba0756e52f
Autor:
Peter Buchwald, Fulvia Verde, David J. Wiley, Marbelys Rodriguez Pino, Dimitrios Vavylonis, Illyce Nuñez, Maitreyi Das, Gennaro D'Urso, Chuan Chen
The highly conserved small GTPase Cdc42 regulates polarized cell growth and morphogenesis from yeast to humans. We previously reported that Cdc42 activation exhibits oscillatory dynamics inSchizosaccharomyces pombecells. Mathematical modeling suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908997f9bb23b328041eee103bbed8e9
https://doi.org/10.1101/2020.06.16.151308
https://doi.org/10.1101/2020.06.16.151308
Autor:
Marbelys Rodriguez Pino, David J. Wiley, Dimitrios Vavylonis, Chuan Chen, Peter Buchwald, Illyce Nuñez, Maitreyi Das, Gennaro D'Urso, Fulvia Verde
Publikováno v:
Molecular Biology of the Cell
The highly conserved small GTPase Cdc42 regulates polarized cell growth and morphogenesis from yeast to humans. We previously reported that Cdc42 activation exhibits oscillatory dynamics at cell tips of Schizosaccharomyces pombe cells. Mathematical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff189178d52416bc97bd89529da01474
https://doi.org/10.1091/mbc.e20-10-0666
https://doi.org/10.1091/mbc.e20-10-0666
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-15 (2019)
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-15 (2019)
Background Gene networks in living cells can change depending on various conditions such as caused by different environments, tissue types, disease states, and development stages. Identifying the differential changes in gene networks is very importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53c63265e1269ce068bfe35d347635e
https://doi.org/10.1186/s12859-019-2749-x
https://doi.org/10.1186/s12859-019-2749-x
Autor:
Gennaro D'Urso, Valeria A. Copello, Ning Zhao, Laine Heidman, Kerry L. Burnstein, David J. Wiley, Stephanie Peacock, Fiorella Magani, Eric R. Bray, Maria J. Martinez
Publikováno v:
Molecular Systems Biology
Identifying critical pathways governing disease progression is essential for accurate prognosis and effective therapy. We developed a broadly applicable and novel systems‐level gene discovery strategy. This approach focused on constitutively active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624e72dfa9f67b67e3c60840448e081e
https://pubmed.ncbi.nlm.nih.gov/30108134
https://pubmed.ncbi.nlm.nih.gov/30108134
Autor:
David J. Wiley, Mary Ellen Ahearn, Gennaro D'Urso, Jesse M. Hunter, Lisa Baumbach-Reardon, Chris Balak
Publikováno v:
F1000Research
Background:X-linked spinal muscular atrophy (XL-SMA) results from mutations in the Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1). Previously, four novel closely clustered mutations have been shown to cause this fatal infantile disorder affecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184921634206102d89c288155f1d2738
http://europepmc.org/articles/PMC5615770
http://europepmc.org/articles/PMC5615770