Výsledky vyhledávání - "Gennady N. Timoshenko"

Increase of mtDNA number and its mutant copies in rat brain after exposure to 150 MeV protons

Autor: S. A. Abdullaev, Tatiana Bulanova, Gennady N. Timoshenko, Azhub I. Gaziev

Publikováno v: Molecular Biology Reports. 47:4815-4820

Proton beam therapy is widely used for treating brain tumor. Despite the efficacy of treatment, the use of this therapy has met some limitations associated with possible damage to normal brain tissues located beyond the tumor site. In this context, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fdae96085b5c4b22ec254c9e6a66fdd
https://doi.org/10.1007/s11033-020-05491-7

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HEMATOLOGICAL, BIOCHEMICAL AND MOLECULAR EFFECTS OF PRIMATE'S HEAD IRRADIATION WITH HIGH-ENERGY KRYPTON NUCLEI

Autor: I.N. Klots, V. S. Kudrin, I. V. Koshlan, Yu. V. Bogdanova, Gennady N. Timoshenko, E. I. Yashkina, A. S. Shtemberg, B. A. Lapin, А.А. Perevezentsev, A.N. Osipov, A. G. Belyaeva, T.M. Blokhina, N. A. Koshlan, A. S. Bazyan

Publikováno v: Aerospace and Environmental Medicine. 54:38-45

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f66729f3f7702ba461d6b24768d2f9e5
https://doi.org/10.21687/0233-528x-2020-54-1-38-45

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A new type of ground-based simulator of radiation field inside a spacecraft in deep space

Autor: Gennady N. Timoshenko, I.S. Gordeev

Publikováno v: Life sciences in space research. 30

The problem of full-scale ground-based modeling of cosmic radiation on heavy-ion accelerators for space radiobiology is very urgent. A new type of space radiation simulator at the 56Fe ion beam with energy 1 GeV/n is proposed. The simulator uses rota

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1235eebace5e498ba02cb7198cb6ee6
https://pubmed.ncbi.nlm.nih.gov/34281666

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Effects of combined exposure to modeled radiation and gravitation factors of the interplanetary flight: Monkeys' cognitive functions and the content of monoamines and their metabolites; cytogenetic changes in peripheral blood lymphocytes

Autor: Gennady N. Timoshenko, Alexandr A. Perevezentsev, Yulia V. Bogdanova, A. S. Shtemberg, Evgeny Krasavin, I. V. Koshlan, V. S. Kudrin, E. I. Yashkina, Mariya D. Isakova, N. A. Koshlan, Andrey N. Nosovsky, A. G. Belyaeva, Taisia Blokhina, Andreyan N. Osipov

Publikováno v: Life sciences in space research. 30

In a study on primates (Macaca mulatta), neurobiological and radiobiological effects have been studied of the synchronous combined action of 7-day antiorthostatic hypokinesia and exposure of the monkeys' head first to γ-rays during 24 h and then to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5554e4657b821198b02fd011bb0efcf
https://pubmed.ncbi.nlm.nih.gov/34281664

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Author Correction: Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context

Autor: Judit E. Šponer, Raffaele Saladino, Gennady N. Timoshenko, Jiří Šponer, Ernesto Di Mauro, Anna Maria Timperio, Alexei Yu. Rozanov, Eugene Krasavin, M. I. Kapralov, Bruno Mattia Bizzarri, Lorenzo Botta, Thomas Georgelin, Maguy Jaber, Baptiste Rigaud

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.4649. ⟨10.1038/s41598-019-40290-6⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6be910a188411d02a46f69e0c765d2
https://hal.archives-ouvertes.fr/hal-02543419

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The effects of high-energy protons and carbon ions (12C) on the cognitive function and the content of monoamines and their metabolites in peripheral blood in monkeys

Autor: V. S. Kudrin, B. A. Lapin, A. S. Shtemberg, O. N. Vasil’eva, A. M. Nosovskii, Gennady N. Timoshenko, Yu. V. Gordeev, Evgeny Krasavin, A. S. Bazyan, A. G. Belyaeva, V. B. Narkevich

Publikováno v: Neurochemical Journal. 11:168-175

Model experiments using monkeys (rhesus macaque monkeys) were performed to investigate the neurobiological effects of two components of galactic cosmic radiation, namely, high-energy protons and carbon (12C) ions. It has been demonstrated that the ir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::002b50b8fbbb5cc50e65ed18a216190d
https://doi.org/10.1134/s1819712417010032

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Meteorite‐Assisted Phosphorylation of Adenosine Under Proton Irradiation Conditions

Autor: Bruno Mattia Bizzarri, Gennady N. Timoshenko, Judit E. Šponer, Eugene Krasavin, Anna Maria Timperio, Michail Kapralov, Ernesto Di Mauro, Jiri Sponer, Giuseppina Fanelli, Giuseppe Cassone, Raffaele Saladino

The abiotic phosphorylation of nucleosides is a major hurdle in origin‐of‐life studies. We suggest a plausible pathway for the synthesis of adenosine nucleotides from adenosine and NaH2PO4under radiative conditions mimicking the solar wind in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ddd4cd5c5c38e448e90f2b755a73de
https://zenodo.org/record/3835518

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Exposure to 12 C particles alters the normal dynamics of brain monoamine metabolism and behaviour in rats

Autor: Eugene Krasavin, Yury S. Severiukhin, Gennady N. Timoshenko, A. S. Bazyan, Kudrin Vs, Viktor B. Narkevich, Aleksandr A. Ivanov, Ksenia Belokopytova, Oleg Belov

Publikováno v: Physica Medica. 32:1088-1094

Planning of the deep-space exploration missions raises a number of questions on the radiation protection of astronauts. One of the medical concerns is associated with exposure of a crew to highly energetic particles of galactic cosmic rays. Among man

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e5bd0ae31e24c0000d2224e75a3763
https://doi.org/10.1016/j.ejmp.2016.08.006

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The dynamics of monoamine metabolism in rat brain structures in the late period after exposure to accelerated carbon ions

Autor: Evgeny Krasavin, Oleg Belov, A. S. Bazyan, V. S. Kudrin, Ksenia Belokopytova, V. B. Narkevich, Gennady N. Timoshenko

Publikováno v: Neurochemical Journal. 10:137-143

We studied the effect of carbon ions (12C) with an energy of 500 MeV/nucleon at a dose of 1 Gy on monoamine metabolism in the brains of rats of different ages. Neurochemical parameters that characterize the distribution of noradrenaline (NA), dopamin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::398d01278dfaa099f0689f4719e615b5
https://doi.org/10.1134/s1819712416020021

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Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context

Autor: Anna Maria Timperio, Judit E. Šponer, M. I. Kapralov, Eugene Krasavin, Maguy Jaber, Jiří Šponer, Bruno Mattia Bizzarri, Lorenzo Botta, Ernesto Di Mauro, Baptiste Rigaud, Raffaele Saladino, Alexei Yu. Rozanov, Thomas Georgelin, Gennady N. Timoshenko

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-15392-8⟩
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-15392-8⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)

The formation of nucleosides in abiotic conditions is a major hurdle in origin-of-life studies. We have determined the pathway of a general reaction leading to the one-pot synthesis of ribo- and 2′-deoxy-ribonucleosides from sugars and purine nucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaa821b3b57708e1d08957d8888d4f7
https://hal.archives-ouvertes.fr/hal-01651973

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