Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gennady G. Fedonin"'
Autor:
Alexey D Neverov, Anfisa V Popova, Gennady G Fedonin, Evgeny A Cheremukhin, Galya V Klink, Georgii A Bazykin
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1008711 (2021)
The rate of evolution differs between protein sites and changes with time. However, the link between these two phenomena remains poorly understood. Here, we design a phylogenetic approach for distinguishing pairs of amino acid sites that evolve conco
Externí odkaz:
https://doaj.org/article/9cc64cb92bdf4e61a6b75d9ee81fa6b6
Autor:
Galya V, Klink, Ksenia, Safina, Elena, Nabieva, Nikita, Shvyrev, Sofya, Garushyants, Evgeniia, Alekseeva, Andrey B, Komissarov, Daria M, Danilenko, Andrei A, Pochtovyi, Elizaveta V, Divisenko, Lyudmila A, Vasilchenko, Elena V, Shidlovskaya, Nadezhda A, Kuznetsova, Andrei E, Samoilov, Alexey D, Neverov, Anfisa V, Popova, Gennady G, Fedonin, Vasiliy G, Akimkin, Dmitry, Lioznov, Vladimir A, Gushchin, Vladimir, Shchur, Georgii A, Bazykin
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
BackgroundDelta has outcompeted most preexisting variants of SARS-CoV-2, becoming the globally predominant lineage by mid-2021. Its subsequent evolution has led to emergence of multiple sublineages, many of which are well-mixed between countries.AimH
Autor:
Fedor Gusev, Denis A. Reshetov, Evgeny I. Rogaev, Zhiping Weng, Andrey Goltsov, Anastasia P. Grigorenko, Tatiana Andreeva, Maria Aliseychik, Amanda C. Mitchell, Gennady G. Fedonin, Leonid Brizgalov, Elena Filippova, Tobias B. Halene, Victor V. Solovyev, Schahram Akbarian, Aslihan Dincer
Publikováno v:
The FASEB Journal. 33:8161-8173
Human prefrontal cortex (PFC) is associated with broad individual variabilities in functions linked to personality, social behaviors, and cognitive functions. The phenotype variabilities associated with brain functions can be caused by genetic or epi
Autor:
Ekaterina E Khrameeva, Andrey A Mironov, Gennady G Fedonin, Philipp Khaitovich, Mikhail S Gelfand
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33947 (2012)
Recent studies demonstrate that the organization of the chromatin within the nuclear space might play a crucial role in the regulation of gene expression. The ongoing progress in determination of the 3D structure of the nuclear chromatin allows one t
Externí odkaz:
https://doaj.org/article/e334ab167bb14a00ac9303822a5aa57b
Autor:
Konstantin V. Gunbin, Fedor Gusev, Mikhail P. Ponomarenko, Gennady G. Fedonin, V. V. Suslov, Evgeny I. Rogaev
Publikováno v:
Molecular Neurobiology. 55:1871-1904
Adaptability to a variety of environmental conditions is a prominent feature of Homo sapiens. We hypothesize that this feature can be explained by evolutionary changes in gene promoters active in the brain prefrontal cortex leading to a more flexible
Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia
Autor:
Tobias B. Halene, Denis A. Reshetov, Gennady G. Fedonin, Schahram Akbarian, Zhiping Weng, Tatiana Andreeva, Evgeny I. Rogaev, Elena Filippova, Amanda C. Mitchell, Fedor Gusev, Anastasia P. Grigorenko, Aslihan Dincer, Maria Aliseychik
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 9, Iss 1, Pp 1-10 (2019)
Translational Psychiatry, Vol 9, Iss 1, Pp 1-10 (2019)
Both heritability and environment contribute to risk for schizophrenia. However, the molecular mechanisms of interactions between genetic and non-genetic factors remain unclear. Epigenetic regulation of neuronal genome may be a presumable mechanism i
Autor:
Kamil Khafizov, Anna V. Valdokhina, Victoria P. Bulanenko, Alexey D. Neverov, Anatoly P. Gmyl, Anna S. Speranskaya, Alexander N. Lukashev, Ekaterina V. Pimkina, Marina V. Safonova, Gennady G. Fedonin, Lubov I. Kozlovskaya, Vladimir G. Dedkov, Alina D. Matsvay, Galina G. Karganova
Publikováno v:
Ticks and tick-borne diseases. 11(2)
Kemerovo virus (KEMV) is a member of the Great Island virus genetic group, belonging to the tick-borne arboviruses of the genus Orbivirus within the family Reoviridae. Nine strains of KEMV, which were isolated from various locations in Russia, were s
Autor:
Anfisa V. Popova, Galya V. Klink, Gennady G. Fedonin, Alexey D. Neverov, Georgii A. Bazykin, E. A. Cheremukhin
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 1, p e1008711 (2021)
PLoS Genetics, Vol 17, Iss 1, p e1008711 (2021)
The rate of evolution differs between protein sites and changes with time. However, the link between these two phenomena remains poorly understood. Here, we design a phylogenetic approach for distinguishing pairs of amino acid sites that evolve conco
Autor:
German A. Shipulin, Kireev De, A.E. Lopatukhin, A.V. Murzakova, Yu. S. Fantin, Anna S. Speranskaya, Gennady G. Fedonin, A.D. Neverov, Ekaterina V. Pimkina
Publikováno v:
Journal of virological methods. 261
The accuracy and sensitivity of deep sequencing were assessed using viral standards (pNL4-3 and pLAI.2) of both DNA and RNA. The sequencing accuracy did not depend on the type of nucleic acid, but critically depended on the number of reads and thresh
Autor:
Alexnader V Favorov, Gennady G. Fedonin, Yury S Fantin, German A. Shipulin, Alexey D. Neverov
Publikováno v:
Briefings in bioinformatics. 20(1)
Characterization of the within-host genetic diversity of viral pathogens is required for selection of effective treatment of some important viral infections, e.g. HIV, HBV and HCV. Despite the technical ability of detection, there are conflicting dat