Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gennady Belitsky"'
Autor:
Olga Vlasova, Irina Antonova, Roman Zenkov, Denis Naberezhnov, Gennady Belitsky, Anna Borunova, Tatiana Zabotina, Daniel García-Gomis, Alfiya Safina, Katerina Gurova, Andrei Gudkov, Kirill Kirsanov, Albert Jordan, Marianna Yakubovskaya
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 8, p 275 (2024)
Background: Many plant secondary metabolites (PSMs) were shown to intercalate into DNA helix or interact with DNA grooves. This may influence histone-DNA interactions changeing chromatin structure and genome functioning. Methods: Nucleosome stability
Externí odkaz:
https://doaj.org/article/0933447b113a4e52b9bc162b82b3b521
Autor:
Varvara Maksimova, Valeriia Popova, Anzhelika Prus, Evgeniya Lylova, Olga Usalka, Guzel Sagitova, Ekaterina Zhidkova, Julia Makus, Ekaterina Trapeznikova, Gennady Belitsky, Marianna Yakubovskaya, Kirill Kirsanov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12874 (2023)
The development of malignant tumors is caused by a complex combination of genetic mutations and epigenetic alterations, the latter of which are induced by either external environmental factors or signaling disruption following genetic mutations. Some
Externí odkaz:
https://doaj.org/article/159e635a85174b80b1942f66dae7d42c
Autor:
Kirill Kirsanov, Timur Fetisov, Elena Antoshina, Lubov Trukhanova, Tatiana Gor’kova, Olga Vlasova, Irina Khitrovo, Ekaterina Lesovaya, Nataliya Kulbachevskaya, Tatiana Shcherbakova, Gennady Belitsky, Marianna Yakubovskaya, Vytas Švedas, Dmitry Nilov
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
7-Methylguanine (7-MG) competitively inhibits the DNA repair enzyme poly(ADP-ribose) polymerase (PARP) and RNA-modifying enzyme tRNA-guanine transglycosylase (TGT) and represents a potential anticancer drug candidate. Furthermore, as a natural compou
Externí odkaz:
https://doaj.org/article/7294f36025d44385b80528fb3d54bae7
Autor:
Varvara Maksimova, Natalya Shalginskikh, Olga Vlasova, Olga Usalka, Anastasia Beizer, Polina Bugaeva, Dmitry Fedorov, Olga Lizogub, Ekaterina Lesovaya, Richard Katz, Gennady Belitsky, Kirill Kirsanov, Marianna Yakubovskaya
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252504 (2021)
Chemicals reactivating epigenetically silenced genes target diverse classes of enzymes, including DNMTs, HDACs, HMTs and BET protein family members. They can strongly influence the expression of genes and endogenous retroviral elements with concomita
Externí odkaz:
https://doaj.org/article/32861914037347c3abf81116c4f0a3d5
Autor:
Kirill Kirsanov, Timur Fetisov, Elena Antoshina, Lubov Trukhanova, Tatiana Gor’kova, Olga Vlasova, Irina Khitrovo, Ekaterina Lesovaya, Nataliya Kulbachevskaya, Tatiana Shcherbakova, Gennady Belitsky, Marianna Yakubovskaya, Vytas Švedas, Dmitry Nilov
Publikováno v:
Frontiers in pharmacology. 13
7-Methylguanine (7-MG) competitively inhibits the DNA repair enzyme poly(ADP-ribose) polymerase (PARP) and RNA-modifying enzyme tRNA-guanine transglycosylase (TGT) and represents a potential anticancer drug candidate. Furthermore, as a natural compou