Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gennady A. Belitsky"'
Autor:
Ekaterina A. Lesovaya, Timur I. Fetisov, Beniamin Yu. Bokhyan, Varvara P. Maksimova, Evgeny P. Kulikov, Gennady A. Belitsky, Kirill I. Kirsanov, Marianna G. Yakubovskaya
Publikováno v:
Cells, Vol 13, Iss 20, p 1695 (2024)
Synovial sarcoma (SS) is one of the most common types of pediatric soft tissue sarcoma (STS) being far less frequent in adults. This STS type is characterized by one specific chromosomal translocation SS18-SSX and the associated changes in signaling.
Externí odkaz:
https://doaj.org/article/9ddb95398b384953a65821cc12e4ce2b
Autor:
Timur I. Fetisov, Anna A. Borunova, Alina S. Antipova, Elena E. Antoshina, Lubov S. Trukhanova, Tatyana G. Gorkova, Svetlana N. Zuevskaya, Alexei Maslov, Katerina Gurova, Andrei Gudkov, Ekaterina A. Lesovaya, Gennady A. Belitsky, Marianna G. Yakubovskaya, Kirill I. Kirsanov
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 230 (2023)
The anticancer activity of Curaxin CBL0137, a DNA-binding small molecule with chromatin remodulating effect, has been demonstrated in different cancers. Herein, a comparative evaluation of CBL0137 activity was performed in respect to acute myeloid le
Externí odkaz:
https://doaj.org/article/2f23be8ffe4d44358670b9b012cc3676
Autor:
Ekaterina M Zhidkova, Evgeniya S Lylova, Alena V Savinkova, Sergey A Mertsalov, Kirill I Kirsanov, Gennady A Belitsky, Marianna G Yakubovskaya, Ekaterina A Lesovaya
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 14 (2020)
Glucocorticoids (GCs) are stress hormones that play multiple roles in the regulation of cancer cell differentiation, apoptosis, and proliferation. Some types of cancers, such as hematological malignancies, can be effectively treated by GCs, whereas t
Externí odkaz:
https://doaj.org/article/acffbb957f7e4348834e8168b5fd0156
Autor:
Kirill I. Kirsanov, Ekaterina A. Lesovaya, Timur I. Fetisov, Beniamin Yu Bokhyan, Gennady A. Belitsky, Marianna G. Yakubovskaya
Publikováno v:
Sarcoma, Vol 2020 (2020)
Soft tissue sarcomas (STS) are a highly heterogeneous group of cancers of mesenchymal origin with diverse morphologies and clinical behaviors. While surgical resection is the standard treatment for primary STS, advanced and metastatic STS patients ar
Externí odkaz:
https://doaj.org/article/ad3667d4ce6a42ae94070fad485d78b3
Autor:
Roman G. Zenkov, Olga A. Vlasova, Varvara P. Maksimova, Timur I. Fetisov, Natalia Y. Karpechenko, Lidiya V. Ektova, Vera A. Eremina, Valeriia G. Popova, Olga G. Usalka, Ekaterina A. Lesovaya, Gennady A. Belitsky, Marianna G. Yakubovskaya, Kirill I. Kirsanov
Publikováno v:
Molecules, Vol 26, Iss 23, p 7329 (2021)
Novel indolocarbazole derivatives named LCS were synthesized by our research group. Two of them were selected as the most active anticancer agents in vivo. We studied the mechanisms of anticancer activity in accordance with the previously described e
Externí odkaz:
https://doaj.org/article/84e2607c91ea44b1b4fe81b35f92e38d
Autor:
Marianna G. Yakubovskaya, Katerina V. Gurova, Andrei V. Gudkov, Gennady A. Belitsky, Andrei A. Purmal, Andrey Leonov, Roman Ivanov, Elena Shipaeva, Ramiz Salimov, Daria Fleyshman, Alfiya Safina, Olga Morozova, Tatiana Gor'kova, Elena Antoshina, Lubov Trukhanova, Varvara Maksimova, Ekaterina A. Lesovaya, Timur Fetisov, Kirill Kirsanov
Chemoprevention is considered a valid approach to reduce the incidence of colorectal cancer, one of the most common malignancies worldwide. Here, we investigated the tumor-preventive activity of curaxin CBL0137. This compound represents a new class o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d9d0821b6b5cb8fb75aea668ab913b
https://doi.org/10.1158/1940-6207.c.6547412.v1
https://doi.org/10.1158/1940-6207.c.6547412.v1
Autor:
Marianna G. Yakubovskaya, Katerina V. Gurova, Andrei V. Gudkov, Gennady A. Belitsky, Andrei A. Purmal, Andrey Leonov, Roman Ivanov, Elena Shipaeva, Ramiz Salimov, Daria Fleyshman, Alfiya Safina, Olga Morozova, Tatiana Gor'kova, Elena Antoshina, Lubov Trukhanova, Varvara Maksimova, Ekaterina A. Lesovaya, Timur Fetisov, Kirill Kirsanov
Supplemental Table 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d647692b3c8f35584fd231862440ae77
https://doi.org/10.1158/1940-6207.22534220
https://doi.org/10.1158/1940-6207.22534220
Akademický článek
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Autor:
Roman G, Zenkov, Kirill I, Kirsanov, Anna M, Ogloblina, Olga A, Vlasova, Denis S, Naberezhnov, Natalia Y, Karpechenko, Timur I, Fetisov, Ekaterina A, Lesovaya, Gennady A, Belitsky, Nina G, Dolinnaya, Marianna G, Yakubovskaya
Publikováno v:
International journal of molecular sciences. 23(16)
Guanine-rich DNA sequences tending to adopt noncanonical G-quadruplex (G4) structures are over-represented in promoter regions of oncogenes. Ligands recognizing G4 were shown to stabilize these DNA structures and drive their formation regulating expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62cbec59fa5945fd85709fffdc98d6b4
https://pubmed.ncbi.nlm.nih.gov/36012470
https://pubmed.ncbi.nlm.nih.gov/36012470
Autor:
Evgeny M. Kirilin, Timur I. Fetisov, Natalia I. Moiseeva, Ekaterina A. Lesovaya, Lidia A. Laletina, Leyla F. Makhmudova, Angelika E. Manikaylo, Liliya Y. Fomina, Denis A. Burov, Beniamin Yu. Bokhyan, Victoria Y. Zinovieva, Alice S. Vilkova, Larisa V. Mekheda, Nikolay A. Kozlov, Alexander M. Scherbakov, Gennady A. Belitsky, Vytas Švedas, Kirill I. Kirsanov, Marianna G. Yakubovskaya
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1796
Soft tissue sarcomas (STS) are heterogeneous cancers with more than 100 histological subtypes, different in molecular alterations, which make its personalized therapy very complex. Gold standard of chemotherapy for advanced STS includes combinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbd70667df890fbfcd400d087255078
https://pubmed.ncbi.nlm.nih.gov/35406568
https://pubmed.ncbi.nlm.nih.gov/35406568