Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Gennadij Raivich"'
Publikováno v:
Mason, M R J, van Erp, S, Wolzak, K, Behrens, A, Raivich, G & Verhaagen, J 2022, ' The Jun-dependent axon regeneration gene program : Jun promotes regeneration over plasticity ', Human molecular genetics, vol. 31, no. 8, pp. 1242-1262 . https://doi.org/10.1093/hmg/ddab315
Human molecular genetics, 31(8), 1242-1262. Oxford University Press
Human Molecular Genetics, 31, 1242-1262. Oxford University Press
Human molecular genetics, 31(8), 1242-1262. Oxford University Press
Human Molecular Genetics, 31, 1242-1262. Oxford University Press
The regeneration-associated gene (RAG) expression program is activated in injured peripheral neurons after axotomy and enables long-distance axon re-growth. Over 1000 genes are regulated, and many transcription factors are upregulated or activated as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90befd0785edfc8196f9f99b45452bfd
Erratum: The Jun-dependent axon regeneration gene program: Jun promotes regeneration over plasticity
Autor:
Matthew R J Mason, Susan van Erp, Kim Wolzak, Axel Behrens, Gennadij Raivich, Joost Verhaagen
Publikováno v:
Mason, M R J, Van Erp, S, Wolzak, K, Behrens, A, Raivich, G & Verhaagen, J 2022, ' Erratum: The Jun-dependent axon regeneration gene program: Jun promotes regeneration over plasticity ', Human molecular genetics, vol. 31, no. 8, pp. 1356-1356 . https://doi.org/10.1093/hmg/ddac044
In the originally published version of this manuscript, there were errors in the details and enumeration for authors' affiliations.
Publikováno v:
The Journal of Physiology. 596:6043-6062
Hypoxia–ischaemia (HI) is a major cause of neonatal brain injury resulting in cerebral palsy, epilepsy, cognitive impairment and other neurological disabilities. The role of extracellular signal‐regulated kinase (ERK) isoforms and their mitogen
Publikováno v:
The Journal of Physiology
Key points This study identifies phosphorylated extracellular signal‐regulated kinase (ERK) to be immediately diminished followed by a rapid if transient increase for up to 4 h following hypoxic–ischaemic insult (HI) in the neonatal mouse.Phospho
Autor:
Donald Peebles, Sigrun Lange, Mariya Hristova, Gennadij Raivich, Paul R. Thompson, Kate Bennett, Eridan Rocha-Ferreira, Priyanka Mawjee, Laura Thei, Venkataraman Subramanian, Anthony P. Nicholas
Publikováno v:
Journal of Neurochemistry
BASE-Bielefeld Academic Search Engine
BASE-Bielefeld Academic Search Engine
Neonatal hypoxic ischaemic (HI) injury frequently causes neural impairment in surviving infants. Our knowledge of the underlying molecular mechanisms is still limited. Protein deimination is a post-translational modification caused by Ca(+2) -regulat
Publikováno v:
Current Pediatric Reviews. 10:37-47
Neonatal brain injury remains a devastating condition, with poor outcomes despite the institution of an effective neuroprotective strategy of therapeutic hypothermia. There is an urgent need to develop additional neuroprotective strategies and to tai
Autor:
Ashwin Woodhoo, Grzegorz Wicher, Linda Greensmith, Richard Mitter, Kristjan R. Jessen, Peter Arthur-Farraj, Elodie Chabrol, Mark Turmaine, D Wilton, Gennadij Raivich, Billy Jenkins, Susanne Quintes, Annbily Banerjee, Rhona Mirsky, Mary Rahman, Axel Behrens, Morwena Latouche
Publikováno v:
Neuron
Neuron; Vol 75
Neuron; Vol 75
Summary The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration. c-Jun
Autor:
Smriti Patodia, Gennadij Raivich
Publikováno v:
Cell and Tissue Research. 349:15-26
The robust axon regeneration that occurs following peripheral nerve injury is driven by transcriptional activation of the regeneration program and by the expression of a wide range of downstream effector molecules from neuropeptides and neurotrophic
Autor:
A. David Edwards, Nicola J. Robertson, Takenori Kato, S Evans, D Kelen, Gennadij Raivich, Stuart Faulkner, A Kapetanakis, M Chandrasekaran, Mariya Hristova, Alan Bainbridge, Robert D. Sanders, Mervyn Maze, Enrico De Vita, Mengyan Liu, Ernest B. Cady
Publikováno v:
Annals of Neurology. 70:133-150
Objective: Additional treatments for therapeutic hypothermia are required to maximize neuroprotection for perinatal asphyxial encephalopathy. We assessed neuroprotective effects of combining inhaled xenon with therapeutic hypothermia after transient
Autor:
Giles S, Kendall, Mariya, Hristova, Mariya, Hirstova, Sigrun, Horn, Dimitra, Dafou, Alejandro, Acosta-Saltos, Beatriz, Almolda, Virginia, Zbarsky, Prakasham, Rumajogee, Heike, Heuer, Bernardo, Castellano, Klaus, Pfeffer, Sergei A, Nedospasov, Donald M, Peebles, Gennadij, Raivich
Publikováno v:
Laboratory Investigation. 91:328-341
In the current study, we explored the role of TNF cluster cytokines on the lipopolysaccharide (LPS)-mediated, synergistic increase in brain injury after hypoxic ischemic insult in postnatal day 7 mice. Pretreatment with moderate doses of LPS (0.3 μg