Shifts in Serum Bile Acid Profiles Associated With Barrett's Esophagus and Stages of Progression to Esophageal Adenocarcinoma.

Autor: Kumar A; Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA., Gwalani P; Division of Internal Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, USA., Iyer PG; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Wang KK; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Falk GW; Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Ginsberg GG; Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Lightdale CJ; Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA., Del Portillo A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., Lagana SM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., Li Y; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Li H; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Genkinger J; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA., Jin Z; Department of Biostatistics, Columbia University Mailman School of Public Health, New York, New York, USA., Rustgi AK; Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, New York, USA., Wang TC; Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, New York, USA., Wang HH; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, New York, USA.; Department of Systems Biology, Columbia University Irving Medical Center, New Yok, New York, USA., Quante M; University of Freiburg, Freiburg, Germany., Abrams JA; Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York, USA.; Digestive and Liver Disease Research Center, Columbia University Irving Medical Center, New York, New York, USA.

Publikováno v: Clinical and translational gastroenterology [Clin Transl Gastroenterol] 2024 Oct 01; Vol. 15 (10), pp. e1. Date of Electronic Publication: 2024 Oct 01.

Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.

Autor: Ben-Ami R; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Wang QL; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden., Zhang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Supplee JG; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Fahrmann JF; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lehmann-Werman R; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Brais LK; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Nowak J; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Yuan C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Loftus M; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Babic A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Irajizad E; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Davidi T; Sharett Institute of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Zick A; Sharett Institute of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Hubert A; Sharett Institute of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Neiman D; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Piyanzin S; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Gal-Rosenberg O; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Horn A; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Shemer R; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Glaser B; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.; Department of Endocrinology and Metabolism, Hadassah Medical Center, Jerusalem, Israel., Boos N; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Jajoo K; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Lee L; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Clancy TE; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Rubinson DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ng K; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Chabot JA; Department of Surgery, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA., Kastrinos F; Division of Digestive and Liver Diseases, Columbia University Irving Medical Cancer and the Vagelos College of Physicians and Surgeons, New York, New York, USA., Kluger M; Department of Surgery, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA., Aguirre AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Bardeesy N; Massachusetts General Hospital Cancer Center, Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Stanger B; Department of Medicine, Division of Gastroenterology, Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., O'Hara MH; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Till J; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Maitra A; Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA., Carpenter EL; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bullock AJ; Division of Hematology and Oncology, Beth-Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Genkinger J; Department of epidemiology, Mailman school of public health, Columbia university, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia university Irving Medical Center, New York, New York, USA., Hanash SM; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Paweletz CP; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Dor Y; Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel Brian_Wolpin@dfci.harvard.edu yuvald@ekmd.huji.ac.il., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA Brian_Wolpin@dfci.harvard.edu yuvald@ekmd.huji.ac.il.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Publikováno v: Gut [Gut] 2024 Mar 07; Vol. 73 (4), pp. 639-648. Date of Electronic Publication: 2024 Mar 07.

Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.

Autor: Morra A; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Schreurs MAC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Anton-Culver H; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, California, USA., Augustinsson A; Oncology, Clinical Sciences in Lund, Lund University, Lund, Sweden., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tübingen, Tübingen, Germany.; German Cancer Consortium (DKTK), Partner Site Tübingen, German Cancer Research Center (DKFZ), Tübingen, Germany., Broeks A; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Buys SS; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Camp NJ; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Castelao JE; Oncology and Genetics Unit, Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain., Cessna MH; Intermountain Healthcare, Salt Lake City, Utah, USA., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York, USA., Colonna SV; Department of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Cox A; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Sheffield, UK., Cross SS; Department of Neuroscience, Academic Unit of Pathology, University of Sheffield, Sheffield, UK., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Dwek M; School of Life Sciences, University of Westminster, London, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, UK., Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Evans DG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Fehm TN; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Figueroa JD; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK.; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Gago-Dominguez M; Cancer Genetics and Epidemiology Group, SERGAS, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS) Foundation, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain., García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Genkinger J; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Grassmann F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Health and Medical University, Potsdam, Germany., Gündert M; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Hahnen E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Harrington PA; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland., Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Houlston RS; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Howell A; Division of Cancer Sciences, University of Manchester, Manchester, UK., Jakubowska A; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland., Janni W; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Jernström H; Oncology, Clinical Sciences in Lund, Lund University, Lund, Sweden., John EM; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.; Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA., Johnson N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Kristensen VN; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Kurian AW; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.; Division of Oncology, Department of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA., Lambrechts D; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for Cancer Biology, VIB, Leuven, Belgium., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden., Lubiński J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Lux MP; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Biobank of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece., Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada., Muranen TA; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Nevelsteen I; Department of Oncology, Leuven Multidisciplinary Breast Center, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Neven P; Department of Oncology, Leuven Multidisciplinary Breast Center, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Newman WG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Obi N; Institute for Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Olshan AF; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany., Patel AV; Department of Population Science, American Cancer Society, Atlanta, Georgia, USA., Peterlongo P; IFOM ETS - The AIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy., Phillips KA; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, Republic of North Macedonia., Polley EC; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., Presneau N; School of Life Sciences, University of Westminster, London, UK., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Radice P; Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 'Predictive Medicine: Molecular Bases of Genetic Risk', Milan, Italy., Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan., Rhenius V; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Robson M; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece., Sawyer EJ; School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, King's College London, London, UK., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Schuetze S; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany., Scott C; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., Shah M; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Smichkoska S; Medical Faculty, University Clinic of Radiotherapy and Oncology, Ss. Cyril and Methodius University in Skopje, Skopje, Republic of North Macedonia., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK., Teras LR; Department of Population Science, American Cancer Society, Atlanta, Georgia, USA., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands., Tomczyk K; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Tomlinson I; Cancer Research Centre, The University of Edinburgh, Edinburgh, UK., Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Vachon CM; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., van Veen EM; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wendt C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Wildiers H; Department of Oncology, Leuven Multidisciplinary Breast Center, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland., Ziogas A; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, California, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Adank MA; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

Publikováno v: Cancer medicine [Cancer Med] 2023 Aug; Vol. 12 (15), pp. 16142-16162. Date of Electronic Publication: 2023 Jul 03.

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.

Autor: Mueller SH; Institute of Health Informatics, University College London, London, UK., Lai AG; Institute of Health Informatics, University College London, London, UK., Valkovskaya M; Division of Psychiatry, University College London, London, UK., Michailidou K; Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, 2371, Nicosia, Cyprus.; Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, 2371, Nicosia, Cyprus.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Abu-Ful Z; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, 35254, Haifa, Israel., Ahearn TU; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Anton-Culver H; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, 92617, USA., Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040, Minsk, Belarus., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, ON, K7L 3N6, Canada., Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences, Lund University, 222 42, Lund, Sweden., Baert T; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000, Louvain, Belgium., Freeman LEB; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany., Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Benitez J; Biomedical Network On Rare Diseases (CIBERER), 28029, Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029, Madrid, Spain., Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, 450054, Russia., Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, 00290, Helsinki, Finland.; Department of Oncology, Örebro University Hospital, 70185, Örebro, Sweden., Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, 30625, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany., Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark., Bonanni B; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT), 69120, Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Brucker SY; Department of Gynecology and Obstetrics, University of Tübingen, 72076, Tübingen, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, 84112, USA., Castelao JE; Oncology and Genetics Unit, Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, 36312, Vigo, Spain., Chan TL; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong, China.; Department of Molecular Pathology, Hong Kong Sanatorium and Hospital, Hong Kong, China., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Choi JY; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, 03080, Korea.; Cancer Research Institute, Seoul National University, Seoul, 03080, Korea.; Institute of Health Policy and Management, Seoul National University Medical Research Center, Seoul, 03080, Korea., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, 10032, USA., Colonna SV; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, 84112, USA., Cornelissen S; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, The Netherlands., Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA., Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Dörk T; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany., Dossus L; Nutrition and Metabolism Section, International Agency for Research On Cancer (IARC-WHO), 69372, Lyon, France., Dwek M; School of Life Sciences, University of Westminster, London, W1W 6UW, UK., Eccles DM; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK., Ekici AB; Institute of Human Genetics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany., Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany., Evans DG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, 90095, USA., Fletcher O; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK., Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark., Gago-Dominguez M; Genomic Medicine Group, International Cancer Genetics and Epidemiology Group, Fundación Pœblica Galega de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, 15706, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA., Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, 20032, China., García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., García-Sáenz JA; Medical Oncology Department, Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), 28040, Madrid, Spain., Genkinger J; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA., Gentry-Maharaj A; Institute of Clinical Trials and Methodology, University College London, London, WC1V 6LJ, UK., Grassmann F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden.; Health and Medical University, 14471, Potsdam, Germany., Guénel P; Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, INSERM, University Paris-Saclay, 94805, Villejuif, France., Gündert M; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), C08069120, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, 69120, Heidelberg, Germany.; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany., Haeberle L; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany., Hahnen E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden.; Department of Oncology, 118 83, Sšdersjukhuset, Stockholm, Sweden., Harkness EF; Division of Informatics, Imaging and Data Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PT, UK.; Nightingale and Genesis Prevention Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, M23 9LT, UK.; NIHR Manchester Biomedical Research Unit, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK., Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, 70210, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210, Kuopio, Finland., Hartman M; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, 119077, Singapore.; Department of Surgery, National University Health System, Singapore, 119228, Singapore., Hein A; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany., Ho WK; Department of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia Campus, 43500, Semenyih, Selangor, Malaysia.; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya, 47500, Selangor, Malaysia., Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, 3015 GD, The Netherlands., Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376, Stuttgart, Germany.; University of Tübingen, 72074, Tübingen, Germany., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia., Houlston RS; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK., Howell A; Division of Cancer Sciences, University of Manchester, Manchester, M13 9PL, UK., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Huo D; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, 60637, USA., Ito H; Division of Cancer Information and Control, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan., Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center Institute for Cancer Control, Tokyo, 104-0045, Japan., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, 71-252, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, 71-252, Szczecin, Poland., Janni W; Department of Gynaecology and Obstetrics, University Hospital Ulm, 89075, Ulm, Germany., John EM; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94304, USA., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK., Jung A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Kang D; Cancer Research Institute, Seoul National University, Seoul, 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea., Khusnutdinova EK; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, 450054, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, 450000, Russia., Kim SW; Department of Surgery, Daerim Saint Mary's Hospital, Seoul, 07442, Korea., Kitahara CM; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA., Koutros S; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Kristensen VN; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, 0379, Oslo, Norway., Kubelka-Sabit K; Department of Histopathology and Cytology, Clinical Hospital Acibadem Sistina, Skopje, 1000, Republic of North Macedonia., Kurian AW; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94304, USA., Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong, China.; Department of Surgery, The University of Hong Kong, Hong Kong, China.; Department of Surgery and Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China., Lacey JV; Department of Computational and Quantitative Medicine, City of Hope, Duarte, CA, 91010, USA.; City of Hope Comprehensive Cancer Center, City of Hope, Duarte, CA, 91010, USA., Lambrechts D; VIB Center for Cancer Biology, 3001, Louvain, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, 3000, Louvain, Belgium., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, 96813, USA., Li J; Human Genetics Division, Genome Institute of Singapore, Singapore, 138672, Singapore., Linet M; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA., Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376, Stuttgart, Germany.; University of Tübingen, 72074, Tübingen, Germany., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, UK., Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, 70210, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210, Kuopio, Finland.; Biobank of Eastern Finland, Kuopio University Hospital, Kuopio, Finland., Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Margolin S; Department of Oncology, 118 83, Sšdersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, 118 83, Stockholm, Sweden., Matsuo K; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan., Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, 711 10, Heraklion, Greece., Menon U; Institute of Clinical Trials and Methodology, University College London, London, WC1V 6LJ, UK., Muir K; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, UK., Murphy RA; School of Population and Public Health, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.; Cancer Control Research, BC Cancer, Vancouver, BC, V5Z 1L3, Canada., Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, 00290, Helsinki, Finland., Newman WG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK., Niederacher D; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, 40225, Düsseldorf, Germany., O'Brien KM; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA., Obi N; Institute for Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, 60637, USA., Olshan AF; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, 222 42, Lund, Sweden., Park SK; Cancer Research Institute, Seoul National University, Seoul, 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea.; Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, 03080, South Korea., Patel AV; Department of Population Science, American Cancer Society, Atlanta, GA, 30303, USA., Patel A; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Perou CM; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, 1000, Republic of North Macedonia., Presneau N; School of Life Sciences, University of Westminster, London, W1W 6UW, UK., Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, 89075, Ulm, Germany., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale Dei Tumori (INT), 20133, Milan, Italy., Ramachandran D; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany., Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, 54000, Pakistan., Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, 35254, Haifa, Israel., Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, 28222, Madrid, Spain., Ruddy KJ; Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany., Saloustros E; Department of Oncology, University Hospital of Larissa, 411 10, Larissa, Greece., Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA., Sawyer EJ; School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, King's College London, London, SE1 9RT, UK., Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, The Netherlands., Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany., Schneider MO; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany., Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 55905, USA., Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Sharma P; Department of Internal Medicine, Division of Medical Oncology, University of Kansas Medical Center, Westwood, KS, 66205, USA., Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan.; School of Public Health, China Medical University, Taichung, Taiwan., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, G1V 4G2, Canada., Surowy H; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), C08069120, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, 69120, Heidelberg, Germany., Tamimi RM; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, 10065, USA., Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK., Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA., Teo SH; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya, 47500, Selangor, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia., Teras LR; Department of Population Science, American Cancer Society, Atlanta, GA, 30303, USA., Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, 43210, USA., Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands., Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, 110231, Bogota, Colombia., Torres-Mejía G; Center for Population Health Research, National Institute of Public Health, 62100, Cuernavaca, Morelos, Mexico., Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Truong T; Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, INSERM, University Paris-Saclay, 94805, Villejuif, France., Vachon CM; Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN, 55905, USA., Vijai J; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA., Wendt C; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, 118 83, Stockholm, Sweden., Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, 90570, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, 90570, Oulu, Finland., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, 751 05, Uppsala, Sweden., Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Yamaji T; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center Institute for Cancer Control, Tokyo, 104-0045, Japan., Yang XR; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Yu JC; Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114, Taiwan., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Ziogas A; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, 92617, USA., Ziv E; Department of Medicine, Diller Family Comprehensive Cancer Center, Institute for Human Genetics, UCSF Helen, University of California San Francisco, San Francisco, CA, 94115, USA., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK., Hemingway H; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK.; University College London Hospitals Biomedical Research Centre (UCLH BRC), London, UK.; The Alan Turing Institute, London, UK., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Kuchenbaecker KB; Division of Psychiatry, University College London, London, UK. k.kuchenbaecker@ucl.ac.uk.; UCL Genetics Institute, University College London, London, UK. k.kuchenbaecker@ucl.ac.uk.

Publikováno v: Genome medicine [Genome Med] 2023 Jan 26; Vol. 15 (1), pp. 7. Date of Electronic Publication: 2023 Jan 26.

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