Genital Secretion HIV RNA Shedding in HIV-Positive Patients on Ritonavir-Boosted Protease Inhibitor Monotherapy or Standard Combination ART: A Cross-Sectional Sub-Study from the PIVOT Trial

Autor: Vincent Lee, Wolfgang Stöhr, David Dunn, Alejandro Arenas-Pinto, Bridget Ferns, Eleni Nastouli, Nicholas J. Beeching, Rebecca Wiggins, Nicholas I. Paton, Laura Else, Zoe Warwick, Amanda Clarke, Charles J.N. Lacey, Saye Khoo

Publikováno v: Antiviral Therapy. 25:55-59

Background Protease inhibitors (PI) have relatively low penetration into the genital tract, raising concerns about the potential for genital HIV RNA shedding in patients taking PI-based regimens, particularly PI monotherapy (PI-mono). Methods We meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1d16c453537f723ad734f206ad42f4
https://doi.org/10.3851/imp3340

HIV-1 viral load and resistance in genital secretions in patients taking protease-inhibitor-based second-line therapy in Africa

Autor: Nicholas I. Paton, Ismail Senoga, Cissy Kityo, AS Walker, Alejandro Arenas-Pinto, Earnest Trial Team, Marina Giuliano, Marco Floridia, Jennifer Thompson, Mary Abwola, Maria Franca Pirillo, Anne Hoppe, Abbas Lugemwa

Publikováno v: Antiviral therapy, 23(2), 191-195. International Medical Press Ltd

Background HIV is transmitted primarily through sexual intercourse, and the objective of this study was therefore to assess whether there is occult viral replication and resistance in genital secretions in patients on protease inhibitor (PI)-based se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c2c59047f288a1ffbb0a5fcd555c2c
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85047210968&origin=inward

Preparation and evaluation of monoclonal antibodies against chlamydial protease-like activity factor to detect Chlamydia pneumoniae antigen in early pediatric pneumonia

Autor: Haiping Fang, Honglan Li, T. Ding, Jianghua Zheng, Hongzhou Lu, Y. Wu, Zhigang Chen

Publikováno v: European Journal of Clinical Microbiology & Infectious Diseases. 34:1319-1326

Chlamydia pneumoniae causes diseases in humans, including community-acquired pneumonia, bronchitis, and sinusitis. It is also associated with atherosclerosis, coronary heart disease, and hyperlipidemia. In this study, we investigated novel materials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f0a0f587b3efe6a17c2f5cedb0d2a9
https://doi.org/10.1007/s10096-015-2343-8

Longitudinal viral dynamics in semen during early HIV infection

Autor: Morris, Sheldon R, Zhao, Mitchell, Smith, Davey M, Vargas, Milenka V, Little, Susan J, Gianella, Sara

Publikováno v: Morris, SR; Zhao, M; Smith, DM; Vargas, MV; Little, SJ; & Gianella, S. (2017). Longitudinal viral dynamics in semen during early HIV infection. Clinical Infectious Diseases, 64(4), 428-434. doi: 10.1093/cid/ciw784. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6569q9dq
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 64, iss 4
Morris, Sheldon R; Zhao, Mitchell; Smith, Davey M; Vargas, Milenka V; Little, Susan J; & Gianella, Sara. (2017). Longitudinal Viral Dynamics in Semen During Early HIV Infection.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 64(4), 428-434. doi: 10.1093/cid/ciw784. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4tb0d1ht

© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. Background. Multiple viruses coinfect the male genital tract, influencing each other's replication and perhaps affecting human immunodeficiency v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1aad4369dca24f8d854a00297fed4f80
http://www.escholarship.org/uc/item/6569q9dq

Antiretroviral adherence and virologic suppression in partnered and unpartnered HIV-positive individuals in southern Brazil

Autor: Mariana Simon, Pamina M. Gorbach, Ivana Varella, Breno Santos, Marcelo P. Almeida, Tara Kerin, Rita Lira, Eduardo Sprinz, Zoe Baker, Tauí de Melo Rocha, Karin Nielsen-Saines, Maria Cristina Chaves, Marineide Gonçalves de Melo

Publikováno v: PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0212744 (2019)
PloS one, vol 14, iss 2

Background An undetectable serum HIV-1 load is key to effectiveness of antiretroviral (ARV) therapy, which depends on adherence to treatment. We evaluated factors possibly associated with ARV adherence and virologic response in HIV-infected heterosex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2141355164f74a4ebd9b07d08e4dd57a
https://doi.org/10.1371/journal.pone.0212744