Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Genichiro Tsuji"'
Autor:
Genichiro Tsuji, Shogo Nakajima, Koichi Watashi, Shiho Torii, Rigel Suzuki, Takasuke Fukuhara, Nobumichi Ohoka, Takao Inoue, Yosuke Demizu
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 81-84 (2022)
Ciclesonide (Cic) is approved as an inhalant for asthma and was clinically tested as a candidate therapy for coronavirus disease 2019 (COVID-19). Its active metabolite Cic2 was recently reported to suppress genomic RNA replication of severe acute res
Externí odkaz:
https://doaj.org/article/d93413c6ad45412db4458691ac126ef5
Autor:
Hanqiao Xu, Nobumichi Ohoka, Hidetomo Yokoo, Kanako Nemoto, Takashi Ohtsuki, Hiroshi Matsufuji, Mikihiko Naito, Takao Inoue, Genichiro Tsuji, Yosuke Demizu
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Liver X receptors (LXRs) belong to the nuclear hormone receptor superfamily and function as ligand-dependent transcription factors that regulate cholesterol homeostasis, lipid homeostasis, and immune responses. LXR antagonists are promising treatment
Externí odkaz:
https://doaj.org/article/ae88e5afc088454faabd03455637e750
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 6395-6399 (2018)
Externí odkaz:
https://doaj.org/article/30981a11caf24fc9b0d9f5e52a9a06f5
Autor:
Takuji Shoda, Nobumichi Ohoka, Genichiro Tsuji, Takuma Fujisato, Hideshi Inoue, Yosuke Demizu, Mikihiko Naito, Masaaki Kurihara
Publikováno v:
Pharmaceuticals, Vol 13, Iss 3, p 34 (2020)
Targeted protein degradation using small chimeric molecules, such as proteolysis-targeting chimeras (PROTACs) and specific and nongenetic inhibitors of apoptosis protein [IAP]-dependent protein erasers (SNIPERs), is a promising technology in drug dis
Externí odkaz:
https://doaj.org/article/eea8d0eaf35a447d86d0789256ee0c02
Publikováno v:
YAKUGAKU ZASSHI. 143:297-307
Autor:
Hidetomo Yokoo, Seiji Tanaka, Eiichi Yamamoto, Genichiro Tsuji, Yosuke Demizu, Nahoko Uchiyama
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:58-63
Autor:
Nobumichi Ohoka, Masanori Suzuki, Takuya Uchida, Genichiro Tsuji, Yoshinori Tsukumo, Masayuki Yoshida, Takao Inoue, Yosuke Demizu, Hitoshi Ohki, Mikihiko Naito
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1885-1891
Internal tandem duplication (ITD) in the gene encoding FMS-like tyrosine kinase 3 (
Autor:
Haruna Tsujimura, Miyako Naganuma, Nobumichi Ohoka, Takao Inoue, Mikihiko Naito, Genichiro Tsuji, Yosuke Demizu
Publikováno v:
ACS Medicinal Chemistry Letters.
Autor:
Eiichi Yamamoto, Ken-ichi Izutsu, Genichiro Tsuji, Sayaka Masada, Hidetomo Yokoo, Yukihiro Goda, Takashi Hakamatsuka, Nahoko Uchiyama, Yosuke Demizu
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:872-876
N-Nitrosodimethylamine (NDMA) is a probable human carcinogen. This study investigated the root cause of the presence of NDMA in ranitidine hydrochloride. Forced thermal degradation studies of ranitidine hydrochloride and its inherent impurities (Imps