Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Genichi Watanabe"'
Autor:
Miyuki Nakai, Keisuke Oka, Genichi Watanabe, Katsunori Kamei, Norio Tsukada, Ryota Mori, Masahiro Nagaya, Yasumitsu Ukai, Hiroshi Morioka, Nobuyuki Tetsuka, Mitsutaka Iguchi, Tetsuya Yagi
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 28(4)
The spread of third-generation cephalosporin-resistant Gram-negative bacteria is a serious concern in acute and post-acute care settings. This study aimed to understand the epidemiology and molecular background of fecal colonization of resistant Ente
Autor:
Vladimir M. Popov, Richard T. Lee, Maofu Fu, Mathew C. Casimiro, Michael J. Powell, Jaime Lindsay, Francesco Marampon, Genichi Watanabe, Richard G. Pestell, Bianca M. Zani, Carmela Ciccarelli
Publikováno v:
Molecular Biology of the Cell. 19:2566-2578
The PC12 pheochromocytoma cell line responds to nerve growth factor (NGF) by exiting from the cell cycle and differentiating to induce extending neurites. Cyclin D1 is an important regulator of G1/S phase cell cycle progression, and it is known to pl
Autor:
Chris Albanese, Anne T. Reutens, Genichi Watanabe, Kumaravel Somasundaram, Maofu Fu, Maria Avantaggiati, Bayar Thimmapaya, Richard G. Pestell, Mark D'Amico, Richard N. Kitsis, Richard T. Lee, Berthold Henglein
Publikováno v:
Journal of Biological Chemistry. 274:34186-34195
The adenovirus E1A protein interferes with regulators of apoptosis and growth by physically interacting with cell cycle regulatory proteins including the retinoblastoma tumor suppressor protein and the coactivator proteins p300/CBP (where CBP is the
Autor:
Koichi Kato, H. Sasaki, Y Kasuya, Jiro Nakamura, Mikihiro Nakayama, Nihishi Hotta, Genichi Watanabe, T. Komori, Yoji Hamada, Eitaro Nakashima, Sadao Chaya, Keiko Naruse
Publikováno v:
Biochemical and Biophysical Research Communications. 261:853-858
To examine the role of platelet-derived growth factor (PDGF) and the polyol pathway in the growth activity of smooth muscle cells (SMCs), [(3)H]-thymidine incorporation, [(125)I]-PDGF-BB binding and expression of PDGF-beta receptor protein were measu
Autor:
Marc A. Webster, Giorgio Inghirami, Robert J. Stenger, Roger J. Davis, G K Haines, Genichi Watanabe, William J. Muller, Chris Albanese, Richard T. Lee, Richard G. Pestell, Joan S. Brugge
Publikováno v:
Journal of Biological Chemistry. 274:7341-7350
The cyclin D1 gene is overexpressed in breast tumors and encodes a regulatory subunit of cyclin-dependent kinases that phosphorylate the retinoblastoma protein. pp60c-src activity is frequently increased in breast tumors; however, the mechanisms gove
Autor:
Genichi Watanabe, Chris Albanese, Richard T. Lee, Anne T. Reutens, Richard G. Pestell, Gino Vairo, Berthold Henglein
Publikováno v:
Molecular and Cellular Biology. 18:3212-3222
The cyclin D1 gene encodes a regulatory subunit of a multiprotein cyclin D1-dependent kinase (CD1K) holoenzyme complex, which phosphorylates and inactivates the tumor suppressor protein pRB (retinoblastoma protein) (15, 72). pRB phosphorylation is fi
Autor:
Lisa D. Wilsbacher, Pilar Pena, James B. Young, Chris Albanese, Genichi Watanabe, Richard G. Pestell
Publikováno v:
Journal of Biological Chemistry. 272:20063-20069
A broad array of stressors induce ACTH release from the anterior pituitary, with consequent stimulation of the adrenal cortex and release of glucocorticoids critical for survival of the animal. ACTH stimulates adrenocortical gene expression in vivo a
Autor:
Dale B. Hales, Richard T. Lee, Richard G. Pestell, Genichi Watanabe, Xiangquan Li, Karen H. Hales
Publikováno v:
Endocrine. 6:317-324
The immunostimulant tumor necrosis factor-alpha (TNF alpha), produced by monocytes/macrophages in response to inflammatory disorders, regulates gene expression in part through induction of mitogen-activated protein kinases (MAPKs), including the stre
Autor:
Jing Li, Richard G. Pestell, Marsha Rich Rosner, Genichi Watanabe, Wen Xiong, Marc B. Hershenson
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 272:L1205-L1210
We examined the role of cyclin D1 in cultured bovine tracheal myocyte mitogenesis. Immunoblots using a polyclonal antibody against cyclin D1 showed the appearance of this protein 4 h after treatment with platelet-derived growth factor (PDGF), a poten
Autor:
Anthony N. Karnezis, John M. Kyriakis, Richard G. Pestell, I-Wei Shu, Genichi Watanabe, Alan K. Howe, Richard T. Lee, Chris Albanese, Leonard I. Zon, Kathleen Rundell
Publikováno v:
Proceedings of the National Academy of Sciences. 93:12861-12866
Cell-cycle progression is mediated by a coordinated interaction between cyclin-dependent kinases and their target proteins including the pRB and E2F/DP-1 complexes. Immunoneutralization and antisense experiments have established that the abundance of