Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Genhong Di"'
Autor:
Min He, Shuang Hao, LinXiaoxi Ma, BingQiu Xiu, BenLong Yang, ZeHao Wang, JingYan Xue, YaYun Chi, Min Xiong, JiaJian Chen, XiaoYan Huang, XiYu Liu, SongYang Wu, Qin Xiao, Yan Huang, RuoHong Shui, AYong Cao, JunJie Li, GenHong Di, WenTao Yang, Xin Hu, GuangYu Liu, KeDa Yu, YiZhou Jiang, ZhongHua Wang, ZhiMing Shao, Jiong Wu
Publikováno v:
EClinicalMedicine, Vol 74, Iss , Pp 102700- (2024)
Summary: Background: Toripalimab, a novel PD-1 antibody, is approved for treatment of multiple solid tumors; however, its neoadjuvant use with chemotherapy for triple-negative breast cancer (TNBC) remains unevaluated. Additionally, induction chemothe
Externí odkaz:
https://doaj.org/article/8620611ec0bb4bdcbdb47cc79155784e
Publikováno v:
Cancer Medicine, Vol 9, Iss 5, Pp 1903-1910 (2020)
Abstract Purpose Previous studies provide inconsistent interpretations of the effect of inherited genetic factors on the survival and prognosis of patients with breast cancer. The aim of this study was to examine the effect of germline BRCA1 and BRCA
Externí odkaz:
https://doaj.org/article/6ba22c9edf854aa88f04402687ebd5f1
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe prognosis of lymph node-negative triple-negative breast cancer (TNBC) is still worse than that of other subtypes despite adjuvant chemotherapy. Reliable prognostic biomarkers are required to identify lymph node-negative TNBC patients at
Externí odkaz:
https://doaj.org/article/42a66932abec4bfea108a72912254403
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundLittle is known regarding the clinicopathologic characteristics, oncologic outcomes, and treatment strategies that could be ascribed to BRCA mutation in early-onset triple-negative breast cancer (eTNBC).MethodseTNBC patients who underwent B
Externí odkaz:
https://doaj.org/article/78bbedc12e9c465b9507210bc82055ea
Autor:
Jiajia Qiu, Jiaqin Guan, Xiaochen Yang, Jiong Wu, Guangyu Liu, Genhong Di, Canming Chen, Yifeng Hou, Qixia Han, Zhenzhou Shen, Zhimin Shao, Zhen Hu
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158531 (2016)
This study aims to understand the quality of life (QOL) and psychological state (PS) of Chinese breast cancer patients who received BRCA1/2 genetic testing; to examine the psychological changes between BRCA1/2 mutation carriers and non-carriers; and
Externí odkaz:
https://doaj.org/article/e4703448fc644656a303eb24ea92b125
Autor:
Xiaochen Yang, Jiong Wu, Jingsong Lu, Guangyu Liu, Genhong Di, Canming Chen, Yifeng Hou, Menghong Sun, Wentao Yang, Xiaojing Xu, Ying Zhao, Xin Hu, Daqiang Li, Zhigang Cao, Xiaoyan Zhou, Xiaoyan Huang, Zhebin Liu, Huan Chen, Yanzi Gu, Yayun Chi, Xia Yan, Qixia Han, Zhenzhou Shen, Zhimin Shao, Zhen Hu
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125571 (2015)
The genetic etiology of hereditary breast cancer has not been fully elucidated. Although germline mutations of high-penetrance genes such as BRCA1/2 are implicated in development of hereditary breast cancers, at least half of all breast cancer famili
Externí odkaz:
https://doaj.org/article/0902ef4acd924031a6a46be89f04b551
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88853 (2014)
INTRODUCTION: Investigate the patterns of mammographically detected calcifications before and after neoadjuvant chemotherapy (NACT) to determine their value for efficacy evaluation and surgical decision making. METHODS: 187 patients with malignant ma
Externí odkaz:
https://doaj.org/article/6fb03065d4cc4610a6029d98f10c4551
Autor:
Li Chen, Yi-Zhou Jiang, Songyang Wu, Jiong Wu, Genhong Di, Guangyu Liu, Keda Yu, Lei Fan, Junjie Li, Yifeng Hou, Zhen Hu, Canming Chen, Xiaoyan Huang, Ayong Cao, Xin Hu, Shen Zhao, Xiaoyan Ma, Xiaoyu Zhu, Jianjun Zou, Wentao Yang, Zhonghua Wang, Zhi-ming Shao
Publikováno v:
Cancer Research. 82:P2-14
Background Camrelizumab and nab-paclitaxel demonstrated promising anti-tumour activity in refractory metastatic immunomodulatory triple-negative breast cancer (TNBC) in FUTURE trial. Anti-angiogenic agents have been reported to facilitate immune infi
Autor:
Yizhou Shen, Yongxiang Qian, Genhong Di, Jie Chen, Zhi-Ming Shao, Zhebin Liu, Shuang Li, Zhaozhi Yang, Xiaoli Yu, Jiong Wu, Guangyu Liu, Yi-Zhou Jiang, Ke-Da Yu, Ding Ma, Sheng Chen, Miao Mo, Xiaoyan Ma, Ying Zhang
Publikováno v:
Gland Surg
BACKGROUND: To investigate whether the interval between adjuvant chemotherapy (CT) completion and postoperative radiation therapy initiation (ICR) after breast-conserving surgery (BCS) affects ipsilateral breast tumor recurrence (IBTR) or survival. M
Autor:
Tian-Jian Yu, Xiao-Guang Li, Ying-Ying Liu, Xun-Xi Lu, Zhi-Ming Shao, Genhong Di, Xi Jin, Bi Lian, Xin Hu, Yi-Zhou Jiang
Publikováno v:
Cancer Research. 81:5491-5505
Genomic alterations are crucial for the development and progression of human cancers. Copy-number gains found in genes encoding metabolic enzymes may induce triple-negative breast cancer (TNBC) adaptation. However, little is known about how metabolic