Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gengyi Zou"'
Autor:
Bongjun Kim, Yuanjian Huang, Kyung-Pil Ko, Shengzhe Zhang, Gengyi Zou, Jie Zhang, Moon Jong Kim, Danielle Little, Lisandra Vila Ellis, Margherita Paschini, Sohee Jun, Kwon-Sik Park, Jichao Chen, Carla Kim, Jae-Il Park
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cell plasticity, changes in cell fate, is crucial for tissue regeneration. In the lung, failure of regeneration leads to diseases, including fibrosis. However, the mechanisms governing alveolar cell plasticity during lung repair remain elusi
Externí odkaz:
https://doaj.org/article/dc073faf3c6b41ac9927b12392b90d9a
Autor:
Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Youn-Sang Jung, Jinho Jang, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Kwon-Sik Park, Jae-Il Park
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114286- (2024)
Summary: Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, some lung adenocarcinoma (LUAD) cells transform into neuroendocrine (NE) tumor cells. However, the mechanisms of NE cell plastic
Externí odkaz:
https://doaj.org/article/7beabc5633f54eef9bcd464bc524689b
Autor:
Kyung-Pil Ko, Shengzhe Zhang, Yuanjian Huang, Bongjun Kim, Gengyi Zou, Sohee Jun, Jie Zhang, Yahui Zhao, Cecilia Martin, Karen J. Dunbar, Gizem Efe, Anil K. Rustgi, Hiroshi Nakagawa, Haiyang Zhang, Zhihua Liu, Jae-Il Park
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109795- (2024)
Summary: Despite the promising outcomes of immune checkpoint inhibitors (ICIs), resistance to ICI presents a new challenge. Therefore, selecting patients for specific ICI applications is crucial for maximizing therapeutic efficacy. Herein, we curated
Externí odkaz:
https://doaj.org/article/b0c57a6133c14aa2a1408bad70cd2bfc
Autor:
Shengzhe Zhang, Sung Ho Lee, Litong Nie, Yuanjian Huang, Gengyi Zou, Youn‐Sang Jung, Sohee Jun, Jie Zhang, Esther M. Lien, Junjie Chen, Jae‐Il Park
Publikováno v:
Cancer Communications, Vol 43, Iss 1, Pp 159-163 (2023)
Externí odkaz:
https://doaj.org/article/f5ab10a75cbc4938a7ae90dba61d3d84
Autor:
Gengyi Zou, Jae-Il Park
Publikováno v:
Clinical and Molecular Hepatology, Vol 29, Iss 1, Pp 33-50 (2023)
The liver exhibits the highest recovery rate from acute injuries. However, in chronic liver disease, the long-term loss of hepatocytes often leads to adverse consequences such as fibrosis, cirrhosis, and liver cancer. The Wnt signaling plays a pivota
Externí odkaz:
https://doaj.org/article/4aab421863964bb989ae38ebf351b313
Autor:
Jin Zhao, Hangming Bai, Xiaoyu Li, Jie Yan, Gengyi Zou, Longlong Wang, Xiru Li, Ze Liu, Rong Xiang, Xiang-Lei Yang, Yi Shi
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Abnormally enhanced de novo lipid biosynthesis has been increasingly realized to play crucial roles in the initiation and progression of varieties of cancers including breast cancer. However, the mechanisms underlying the dysregulation of li
Externí odkaz:
https://doaj.org/article/f0ae40b6a7704a3ab372347fe73303bc
Autor:
Xiaotong Zhang, Gengyi Zou, Xiyang Li, Lun Wang, Tianyu Xie, Jin Zhao, Longlong Wang, Shunchang Jiao, Rong Xiang, Haoyu Ye, Yi Shi
Publikováno v:
Cancer Biology & Medicine, Vol 17, Iss 3, Pp 693-706 (2020)
Objective: Angiogenesis plays a vital role in tumor growth and metastasis. Here, we aimed to find novel efficient antiangiogenic molecules targeting vascular endothelial growth factor A (VEGFA ) at the transcriptional level to treat triple-negative b
Externí odkaz:
https://doaj.org/article/3e4bf98704a74c92859c346fc39901ea
Autor:
Jae-Il Park, Shengzhe Zhang, Sung Ho Lee, Litong Nie, Yuanjian Huang, Gengyi Zou, Youn-Sang Jung, Sohee Jun, Jie Zhang, Esther Lien, Junjie Chen
Publikováno v:
Cancer Communications. 43:159-163
Lysosomes play vital roles in the degradation and recycling of various macromolecules, protein secretion, energy metabolism, and cell signaling. Increasing evidence suggests that the deregulated lysosomes contribute to tumorigenesis and therapeutic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1cb165c2d9ca3c0bb7d04a664153dd6
https://doi.org/10.1002/cac2.12382
https://doi.org/10.1002/cac2.12382
Autor:
Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Youn-Sang Jung, Kwon-Sik Park, Jae-Il Park
Publikováno v:
bioRxiv
Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, lung adenocarcinoma (LUAD) cells transform into neuroendocrinal (NE) tumor cells. However, the mechanisms of NE cell plasticity remain un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49c0202ce763c03300f67d882d9dd9e
https://europepmc.org/articles/PMC10153265/
https://europepmc.org/articles/PMC10153265/
Autor:
Kyung-Pil Ko, Shengzhe Zhang, Yuanjian Huang, Bongjun Kim, Gengyi Zou, Sohee Jun, Jie Zhang, Cecilia Martin, Karen J. Dunbar, Gizem Efe, Anil K. Rustgi, Haiyang Zhang, Hiroshi Nakagawa, Jae-Il Park
Publikováno v:
bioRxiv
SummaryDespite the promising outcomes of immune checkpoint blockade (ICB), resistance to ICB presents a new challenge. Therefore, selecting patients for specific ICB applications is crucial for maximizing therapeutic efficacy. Herein we curated 69 hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a74326848f597eda23a7463ce2e500a
https://doi.org/10.1101/2023.02.15.528539
https://doi.org/10.1101/2023.02.15.528539