Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gengxiang Zhao"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Chrysophaeum taylorii is a member of an understudied clade of marine algae that can be responsible for harmful coastal blooms and is known to accumulate bioactive natural products including antibiotics of the chrysophaentin class. Whole geno
Externí odkaz:
https://doaj.org/article/22aa6a229fe34ab8b665b75e83947d3a
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small.
Externí odkaz:
https://doaj.org/article/5ffe78d07adf48b2b0c132fc30977b27
Autor:
Hong-Bing Liu, Jack R. Davison, Rahim Rajwani, Gengxiang Zhao, Shannon I. Ohlemacher, Robert D. O’Connor, Carole A. Bewley
Publikováno v:
Molecules, Vol 26, Iss 23, p 7197 (2021)
Pyrazines (1,4-diazirines) are an important group of natural products that have tremendous monetary value in the food and fragrance industries and can exhibit a wide range of biological effects including antineoplastic, antidiabetic and antibiotic ac
Externí odkaz:
https://doaj.org/article/3bc463172bac459c87fa2bfa9aca2c05
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70369 (2013)
N-acetylglutamate synthase (NAGS) catalyzes the conversion of AcCoA and L-glutamate to CoA and N-acetyl-L-glutamate (NAG), an obligate cofactor for carbamyl phosphate synthetase I (CPSI) in the urea cycle. NAGS deficiency results in elevated levels o
Externí odkaz:
https://doaj.org/article/c04939634cc44988a43f269b9a8255cd
Autor:
Dashuang Shi, Yongdong Li, Juan Cabrera-Luque, Zhongmin Jin, Xiaolin Yu, Gengxiang Zhao, Nantaporn Haskins, Norma M Allewell, Mendel Tuchman
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28825 (2011)
Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, we
Externí odkaz:
https://doaj.org/article/de8dae987bdc4042b99fb83b43ae9ad3
Autor:
Carole A. Bewley, Jiadong Sun, Clifton E. Barry, Anastasia N. Nikolskaya, Kira S. Makarova, Dalibor Kosek, Fred Dyda, Brittney Blackburne, Hong-Bing Liu, Gengxiang Zhao, Eugene V. Koonin, Shannon I. Ohlemacher
Publikováno v:
J Am Chem Soc
Among the ribosomally synthesized and post-translationally modified peptide (RiPP) natural products, “graspetides” (formerly known as microviridins) contain macrocyclic esters and amides that are formed by ATP-grasp ligase tailoring enzymes using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a92a2265b11c51d598728997168ea4
https://doi.org/10.1021/jacs.1c02316
https://doi.org/10.1021/jacs.1c02316
Autor:
Jiadong Sun, Gengxiang Zhao, Tatsiana Bylund, Myungjin Lee, Srikar Adibhatla, Peter D. Kwong, Gwo-Yu Chuang, Reda Rawi, Carole A. Bewley
Publikováno v:
ACS Chem Biol
Lectins, carbohydrate-binding proteins of nonimmune origin, bind to carbohydrates and glycan shields present on the surfaces of cells and viral spike proteins. Lectins thus hold great promise as therapeutic and diagnostic proteins, exemplified by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03809f78b538f6f728fb52fc94caf392
https://europepmc.org/articles/PMC10091857/
https://europepmc.org/articles/PMC10091857/
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
mSystems
mSystems
Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small. To obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9592a9250621e5b3c259baf3dd571e4b
https://doi.org/10.1128/msystems.01020-21
https://doi.org/10.1128/msystems.01020-21
Genome-mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as Actinomycetes, relative to human pathogens with smaller genomes, is small. To obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee5875bff2831d5648f3ed86ea307373
https://doi.org/10.1101/2021.08.11.456034
https://doi.org/10.1101/2021.08.11.456034
Publikováno v:
Org Lett
Six novel pyranonaphthoquinones, vertirhodins A-F (1-6), were discovered from a soil-derived Streptomyces sp. B15-008. Their chemical structures and absolute configurations were determined using nuclear magnetic resonance and comparison of experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b64d695667db2bc28289da2702a5d7b
https://europepmc.org/articles/PMC9394642/
https://europepmc.org/articles/PMC9394642/