Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gengqiang Xie"'
Autor:
Gengqiang Xie, Maria Pilar Toledo, Xue Hu, Hyo Jeong Yong, Pamela Sandoval Sanchez, Chengyang Liu, Ali Naji, Jerome Irianto, Yue J. Wang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Current approaches to profile the single-cell transcriptomics of human pancreatic endocrine cells almost exclusively rely on freshly isolated islets. However, human islets are limited in availability. Furthermore, the extensive pr
Externí odkaz:
https://doaj.org/article/3d422116a8064f6a8eb95b7ea0f0f65f
Autor:
Olalekan H. Usman, Liting Zhang, Gengqiang Xie, Hemant M. Kocher, Chang-il Hwang, Yue Julia Wang, Xian Mallory, Jerome Irianto
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract The establishment of patient-derived pancreatic cancer organoid culture in recent years creates an exciting opportunity for researchers to perform a wide range of in vitro studies on a model that closely recapitulates the tumor. One of the o
Externí odkaz:
https://doaj.org/article/3a41ca1bac8a43188228952c1df43c8d
Autor:
Hyo Jeong Yong, Gengqiang Xie, Chengyang Liu, Wei Wang, Ali Naji, Jerome Irianto, Yue J. Wang
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
NEUROGENIN3+ (NEUROG3+) cells are considered to be pancreatic endocrine progenitors. Our current knowledge on the molecular program of NEUROG3+ cells in humans is largely extrapolated from studies in mice. We hypothesized that single-cell RNA-seq ena
Externí odkaz:
https://doaj.org/article/ec5087b5e5784e34af299c119b9f8477
Autor:
Allison Jevitt, Deeptiman Chatterjee, Gengqiang Xie, Xian-Feng Wang, Taylor Otwell, Yi-Chun Huang, Wu-Min Deng
Publikováno v:
PLoS Biology, Vol 18, Iss 4, p e3000538 (2020)
Oogenesis is a complex developmental process that involves spatiotemporally regulated coordination between the germline and supporting, somatic cell populations. This process has been modeled extensively using the Drosophila ovary. Although different
Externí odkaz:
https://doaj.org/article/c157d77414ff49d590e8b47ae7a2c198
Autor:
Phuong Thao Ly, Ye Sing Tan, Chwee Tat Koe, Yingjie Zhang, Gengqiang Xie, Sharyn Endow, Wu-Min Deng, Fengwei Yu, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000276 (2019)
The ability of neural stem cells (NSCs) to transit between quiescence and proliferation is crucial for brain development and homeostasis. Drosophila Hippo pathway maintains NSC quiescence, but its regulation during brain development remains unknown.
Externí odkaz:
https://doaj.org/article/e95abb8a797e4b4599072337cfefff5b
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36362 (2012)
BACKGROUND:Notch signaling is a highly conserved pathway in multi-cellular organisms ranging from flies to humans. It controls a variety of developmental processes by stimulating the expression of its target genes in a highly specific manner both spa
Externí odkaz:
https://doaj.org/article/2ea31bb2d6124827b302ec7b9bacc96c
Autor:
Wu-Min Deng, Renjie Jiao, Steven X. Hou, Xiankun Zeng, Yi-Chun Huang, William Hunt Palmer, Zhiqiang Shu, Dongyu Jia, Hanqing Chen, Gengqiang Xie
Legends and methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc23eedf9a8041f9a4438a3a7673283
https://doi.org/10.1158/0008-5472.22414127.v1
https://doi.org/10.1158/0008-5472.22414127.v1
Autor:
Wu-Min Deng, Renjie Jiao, Steven X. Hou, Xiankun Zeng, Yi-Chun Huang, William Hunt Palmer, Zhiqiang Shu, Dongyu Jia, Hanqing Chen, Gengqiang Xie
Supplementary Table 1: The mRNA level changes of representative components or targets of JAK-STAT, JNK, and Notch signaling pathways in snr1-RNAi tumorous wing discs relative to control wildtype wing discs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6faf610364538d4e4b763eb631e3b589
https://doi.org/10.1158/0008-5472.22414115.v1
https://doi.org/10.1158/0008-5472.22414115.v1
Autor:
Wu-Min Deng, Renjie Jiao, Steven X. Hou, Xiankun Zeng, Yi-Chun Huang, William Hunt Palmer, Zhiqiang Shu, Dongyu Jia, Hanqing Chen, Gengqiang Xie
Supplementary file 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd2c116f036a7951adb9fe720691f21
https://doi.org/10.1158/0008-5472.22414118
https://doi.org/10.1158/0008-5472.22414118
Autor:
Wu-Min Deng, Renjie Jiao, Steven X. Hou, Xiankun Zeng, Yi-Chun Huang, William Hunt Palmer, Zhiqiang Shu, Dongyu Jia, Hanqing Chen, Gengqiang Xie
Supplementary figure 1: Snr1 is required for cell survival in Drosophila wing imaginal disc. Supplementary figure 2: Tumorigenic overgrowth in wing discs carrying snr1-depletion by tissue-specific Gal4 drivers. Supplementary figure 3: Coexpression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238ea578c848068cd8eded695e574751
https://doi.org/10.1158/0008-5472.22414121
https://doi.org/10.1158/0008-5472.22414121