Zobrazeno 1 - 10
of 6 525
pro vyhledávání: '"Geng G"'
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Recent studies have shifted the spotlight from adult disease to gametogenesis and embryo developmental events, and these are greatly affected by various environmental chemicals, such as drugs, metabolites, pollutants, and others. Growing res
Externí odkaz:
https://doaj.org/article/6fe029b931814ba4acb13ffd70a9b110
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 727-730 (2023)
Externí odkaz:
https://doaj.org/article/00b7d2a0c0ae4806a7b959b55afeae6b
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Metformin as a first-line clinical anti-diabetic agent prolongs the lifespan of model animals and promotes cell proliferation. However, the molecular mechanisms underlying the proliferative phenotype, especially in epigenetics, ha
Externí odkaz:
https://doaj.org/article/405a383895e04376ab495700cc2d398e
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112403- (2023)
Summary: N6-methyladenosine (m6A) modification controls cell fate determination. Here, we show that liquid-liquid phase separation (LLPS) of YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), a pivotal m6A “reader” protein, promotes the trans
Externí odkaz:
https://doaj.org/article/edef6dc09c674abd8b42aa1aa5f2931b
Autor:
Huacheng Luo, Xiaoyong Li, Geng G. Tian, Dali Li, Changliang Hou, Xinbao Ding, Lin Hou, Qifeng Lyu, Yunze Yang, Austin J. Cooney, Wenhai Xie, Ji Xiong, Hu Wang, Xiaodong Zhao, Ji Wu
Publikováno v:
Journal of Advanced Research, Vol 33, Iss , Pp 81-98 (2021)
Introduction: Fate determination of germline stem cells remains poorly understood at the chromatin structure level. Objectives: Our research hopes to develop successful offspring production of ovarian organoids derived from spermatogonial stem cells
Externí odkaz:
https://doaj.org/article/0a5f8e74bf8348f4a6d4d68409dca27b
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Abstract Background During meiosis of mammalian cells, chromatin undergoes drastic reorganization. However, the dynamics of the three‐dimensional (3D) chromatin structure during the development of female germline stem cells (FGSCs) are poorly under
Externí odkaz:
https://doaj.org/article/2bfe55226587417ba018d5e29122d217
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 431-439 (2021)
N6-methyladenosine (m6A) methylation modification is the most prevalent and abundant internal modification of eukaryotic mRNAs. Increasing evidence has shown that mRNA m6A plays important roles in the development of stem cells. However, to the best o
Externí odkaz:
https://doaj.org/article/f6a69256b2e44feab7018e0d005dd114
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background Preimplantation embryo development is a highly ordered sequence of processes and it requires a precise temporal and spatial control of gene expression. Alternative splicing (AS) is a crucial process that changes the genomic instru
Externí odkaz:
https://doaj.org/article/d385d2454c224dd59a234c1153b6275f
Autor:
Jian Wang, Geng G. Tian, Xiaoyong Li, Yangyang Sun, Li Cheng, Yanfei Li, Yue Shen, Xuejin Chen, Wenwei Tang, Shengce Tao, Ji Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Glycosylation is one of the most fundamental post-translational modifications. However, the glycosylation patterns of glycoproteins have not been analyzed in mammalian preimplantation embryos, because of technical difficulties and scarcity of the req
Externí odkaz:
https://doaj.org/article/27efaf5f2b224f67afe846f1555d0470
Publikováno v:
Data in Brief, Vol 27, Iss , Pp - (2019)
This data descriptor is an extended version of the methodologies which have been described in a related paper [1]; its purpose is to disseminate the raw data and analyzed data produced in this experiment. For more insight please see the research arti
Externí odkaz:
https://doaj.org/article/afa96346510d41b2a18e9dc54a8b1943