Výsledky vyhledávání - "Genevieve Wellner"

Exploring STR signal in the single- and multicopy number regimes: Deductions from an in silico model of the entire DNA laboratory process

Autor: Neil Gurram, Kelsey C. Peters, Catherine M. Grgicak, Genevieve Wellner, Ken R. Duffy

Publikováno v: ELECTROPHORESIS. 38:855-868

Short tandem repeat (STR) profiling from DNA samples has long been the bedrock of human identification. The laboratory process is composed of multiple procedures that include quantification, sample dilution, PCR, electrophoresis, and fragment analysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3825386a24fa32b20aa05ae052ae6ed
https://doi.org/10.1002/elps.201600385

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Exploring the Impacts of Ordinary Laboratory Alterations During Forensic DNA Processing on Peak Height Variation, Thresholds, and Probability of Dropout

Autor: Catherine M. Grgicak, Genevieve Wellner, Kayleigh E. Rowan

Publikováno v: Journal of Forensic Sciences. 61:177-185

Impacts of validation design on DNA signal were explored, and the level of variation introduced by injection, capillary changes, amplification, and kit lot was surveyed by examining a set of replicate samples ranging in mass from 0.25 to 0.008 ng. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdebd029666a26cc8a729c1539758c8f
https://doi.org/10.1111/1556-4029.12899

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A Signal Model for Forensic DNA Mixtures

Autor: Ullrich J. Monich, Catherine M. Grgicak, Muriel Medard, Genevieve Wellner, Ken R. Duffy, Jason Yonglin Wu, Viveck R. Cadambe

Publikováno v: MIT web domain
ACSSC

For forensic purposes, short tandem repeat allele signals are used as DNA fingerprints. The interpretation of signals measured from samples has traditionally been conducted by applying thresholding. More quantitative approaches have recently been dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418043909c918e250167e8b60fe70a30
http://eprints.maynoothuniversity.ie/5981/

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