Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Genevieve Saphier"'
Autor:
Sulagna Ghosh, Seva Kashin, Shila Mekhoubad, Nissim Benvenisty, Kevin Eggan, Genevieve Saphier, Curtis J. Mello, Florian T. Merkle, Maura Charlton, Steven A. McCarroll, Yishai Avior, Nolan Kamitaki, Robert E. Handsaker, Shiran Bar, Jana M. Mitchell, Giulio Genovese, Dusko Ilic
Publikováno v:
Nature. 545:229-233
Human pluripotent stem cells (hPS cells) can self-renew indefinitely, making them an attractive source for regenerative therapies. This expansion potential has been linked with the acquisition of large copy number variants that provide mutated cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ba175c9f08605c68303776a73807e9
https://doi.org/10.1038/nature22312
https://doi.org/10.1038/nature22312
Publikováno v:
CourseSource. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd361792c0fe60c8baffc999217d4a9b
https://doi.org/10.24918/cs.2016.1
https://doi.org/10.24918/cs.2016.1
Autor:
Hiroshi Mitsumoto, Kevin Eggan, Genevieve Saphier, Kathy K. Niakan, Rudy Leibel, Laurin M. Weisenthal, Kit T. Rodolfa, John T. Dimos, Robin Goland, Wendy K. Chung, Christopher E. Henderson, Hynek Wichterle, Gist F. Croft
Publikováno v:
Science. 321:1218-1221
The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's disease. These cells could in turn be used for disease modeling, drug discovery, and eventually a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf72e2a15b3bda5d5d4eb5ab9dd50bc
https://doi.org/10.1126/science.1158799
https://doi.org/10.1126/science.1158799
Autor:
Robin Goland, William G. Kearns, Claire Fitzgerald, Jay B. Patel, Justin K. Ichida, Manfred Baetscher, Kevin Eggan, Kathryn J. Go, Rudolph L. Leibel, Alice E. Chen, Dieter Egli, Nicole Acevedo, Genevieve Saphier, Douglas A. Melton
Publikováno v:
Nature Communications. 2
Fertilized mouse zygotes can reprogram somatic cells to a pluripotent state. Human zygotes might therefore be useful for producing patient-derived pluripotent stem cells. However, logistical, legal and social considerations have limited the availabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e35b6a74a727ea2b7607e1056d8db1f
https://doi.org/10.1038/ncomms1503
https://doi.org/10.1038/ncomms1503
Autor:
Robin Goland, Rudolph L. Leibel, Genevieve Saphier, Michael M. Alper, Brian M. Berger, Kevin Eggan, Douglas Powers, Dieter Egli, Douglas A. Melton, Karin Katz, Alice E. Chen
Publikováno v:
Cell Stem Cell. (4):293-294
We thank a remarkable, anonymous woman for donating her oocytes. This work was supported by the Stowers Medical Institute, the Harvard Stem Cell Institute, the Naomi Berrie Diabetes Center, and the New York Stem Cell Foundation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413adecec332d6cab6c50205d7ae4780