Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Genevieve L, Evans"'
Autor:
Anandhi Anandan, Nicholas W. Dunstan, Timothy M. Ryan, Haydyn D. T. Mertens, Katherine Y. L. Lim, Genevieve L. Evans, Charlene M. Kahler, Alice Vrielink
Publikováno v:
IUCrJ, Vol 8, Iss 5, Pp 732-746 (2021)
Many pathogenic gram-negative bacteria have developed mechanisms to increase resistance to cationic antimicrobial peptides by modifying the lipid A moiety. One modification is the addition of phosphoethanolamine to lipid A by the enzyme phosphoethano
Externí odkaz:
https://doaj.org/article/cbc165d2c27747119717a3d4bd3ba62d
Autor:
Marijke Brams, Cedric Govaerts, Kumiko Kambara, Kerry L Price, Radovan Spurny, Anant Gharpure, Els Pardon, Genevieve L Evans, Daniel Bertrand, Sarah CR Lummis, Ryan E Hibbs, Jan Steyaert, Chris Ulens
Publikováno v:
eLife, Vol 9 (2020)
Pentameric ligand-gated ion channels (pLGICs) or Cys-loop receptors are involved in fast synaptic signaling in the nervous system. Allosteric modulators bind to sites that are remote from the neurotransmitter binding site, but modify coupling of liga
Externí odkaz:
https://doaj.org/article/342cb67467c141c1a4b0ebacf9821115
Autor:
Genevieve L. Evans, Daniel P. Furkert, Nacim Abermil, Preeti Kundu, Katrina M. de Lange, Emily J. Parker, Margaret A. Brimble, Edward N. Baker, J. Shaun Lott
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 1019-1029 (2017)
There are twenty-five published structures of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (Mtb-AnPRT) that use the same crystallization protocol. The structures include protein complexed with natural and alternative substrates,
Externí odkaz:
https://doaj.org/article/5c6539f806014fd3a63a51b4a3d201bc
Autor:
Nicholas W Dunstan, Anandhi Anandan, Timothy M. Ryan, Genevieve L. Evans, Katherine Y. L. Lim, Charlene M. Kahler, Alice Vrielink, Haydyn D. T. Mertens
Publikováno v:
IUCrJ, Vol 8, Iss 5, Pp 732-746 (2021)
IUCrJ
IUCrJ
Small-angle X-ray scattering and tryptophan fluorescence studies of phosphoethanolamine transferase (EptA) suggest conformational flexibility linked to enzyme activity.
Many pathogenic gram-negative bacteria have developed mechanisms to incr
Many pathogenic gram-negative bacteria have developed mechanisms to incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20e334085c90275b6a97598d26964c3
https://doi.org/10.1107/s2052252521005613
https://doi.org/10.1107/s2052252521005613
Autor:
Chris Ulens, Els Pardon, Genevieve L. Evans, D. Bertrand, Kumiko Kambara, Jan Steyaert, Radovan Spurny, Cédric Govaerts, Marijke Brams, Kerry L. Price, Sarah C. R. Lummis, Ryan E. Hibbs, Anant Gharpure
Publikováno v:
eLife, 9
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Pentameric ligand-gated ion channels (pLGICs) or Cys-loop receptors are involved in fast synaptic signaling in the nervous system. Allosteric modulators bind to sites that are remote from the neurotransmitter binding site, but modify coupling of liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f200d44ca2bed9d9f15b016115158c76
https://hdl.handle.net/20.500.14017/ebfd9a6c-7f5a-4ce5-b0f7-d5a8a10d56d2
https://hdl.handle.net/20.500.14017/ebfd9a6c-7f5a-4ce5-b0f7-d5a8a10d56d2
Autor:
Cédric Govaerts, Radovan Spurny, Els Pardon, Sarah C. R. Lummis, Ryan E. Hibbs, Marijke Brams, Daniel Bertrand, Chris Ulens, Kerry L. Price, Kumiko Kambara, Jan Steyaert, Anant Gharpure, Genevieve L. Evans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d0c6450ee6f3fb72e132979c0087082
https://doi.org/10.7554/elife.51511.sa2
https://doi.org/10.7554/elife.51511.sa2
Autor:
Emily J. Parker, J. Shaun Lott, Edward N. Baker, Daniel P. Furkert, Katrina M. de Lange, Margaret A. Brimble, Nacim Abermil, Genevieve L. Evans, Preeti Kundu
Publikováno v:
Data in Brief, Vol 15, Iss, Pp 1019-1029 (2017)
There are twenty-five published structures of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (Mtb-AnPRT) that use the same crystallization protocol. The structures include protein complexed with natural and alternative substrates,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85134d0b60bc5dd8d9315e73b20e6b2
http://www.sciencedirect.com/science/article/pii/S2352340917305723
http://www.sciencedirect.com/science/article/pii/S2352340917305723
Autor:
Grace Brannigan, Luis G. Cuello, Genevieve L. Evans, Argel Estrada-Mondragon, Camille M. Hénault, Kristen N. Woods, Cédric Govaerts, John E. Baenziger, Benjamin W. Elberson, Marijke Brams, Hugues Nury, D. Bertrand, Radovan Spurny, Jan Steyaert, Joseph W. Lynch, Els Pardon, Chris Ulens
Publikováno v:
Nature Chemical Biology, 15 (12
Nature Chemical Biology
Nature Chemical Biology, 2019, 15 (12), pp.1156-1164. ⟨10.1038/s41589-019-0369-4⟩
Nat. Chem. Biol.
Nature Chemical Biology, Nature Publishing Group, 2019, 15 (12), pp.1156-1164. ⟨10.1038/s41589-019-0369-4⟩
Nat Chem Biol
Nature Chemical Biology
Nature Chemical Biology, 2019, 15 (12), pp.1156-1164. ⟨10.1038/s41589-019-0369-4⟩
Nat. Chem. Biol.
Nature Chemical Biology, Nature Publishing Group, 2019, 15 (12), pp.1156-1164. ⟨10.1038/s41589-019-0369-4⟩
Nat Chem Biol
Phospholipids are key components of cellular membranes and are emerging as important functional regulators of different membrane proteins, including pentameric ligand-gated ion channels (pLGICs). Here, we take advantage of the prokaryote channel ELIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b737e5a3ca1fb17e1f23703c9ef72d8e
https://doi.org/10.1038/s41589-019-0369-4
https://doi.org/10.1038/s41589-019-0369-4
Autor:
Anant Gharpure, Els Pardon, Genevieve L. Evans, Marijke Brams, Radovan Spurny, Jan Steyaert, Sarah C. R. Lummis, Daniel Bertrand, Cédric Govaerts, Ryan E. Hibbs, Chris Ulens, Kumiko Kambara, Kerry L. Price
Pentameric ligand-gated ion channels (pLGICs) belong to a class of ion channels involved in fast synaptic signaling in the central and peripheral nervous systems. Molecules acting as allosteric modulators target binding sites that are remote from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20a0856acba74cd3d20e5473cefba55
https://doi.org/10.1101/770719
https://doi.org/10.1101/770719
Autor:
Marijke, Brams, Cedric, Govaerts, Kumiko, Kambara, Kerry L, Price, Radovan, Spurny, Anant, Gharpure, Els, Pardon, Genevieve L, Evans, Daniel, Bertrand, Sarah Cr, Lummis, Ryan E, Hibbs, Jan, Steyaert, Chris, Ulens
Publikováno v:
eLife
Pentameric ligand-gated ion channels (pLGICs) or Cys-loop receptors are involved in fast synaptic signaling in the nervous system. Allosteric modulators bind to sites that are remote from the neurotransmitter binding site, but modify coupling of liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c3ed64939ed2946da544d5f4b660af5
https://pubmed.ncbi.nlm.nih.gov/31990273
https://pubmed.ncbi.nlm.nih.gov/31990273