Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Genevieve Hartley"'
Autor:
Mien-Chie Hung, Junjie Chen, Michael Curran, Nils-Petter Rudqvist, Chao-Hsien Chen, Ronald DePinho, Steven Lin, Akash Boda, Priyamvada Jayaprakash, Brittany Morrow, Rishika Prasad, Anupallavi Srinivasamani, Michelle Winkler, Rodney Cheng-En Hsieh, Sunil Krishnan, Ren-Chin Wu, Arthur Liu, Wen-Hao Hsu, Li-Chuan Chan, Krithikaa Bhanu, Ricardo De Azevedo, Yung-Chih Chou, Matthew Gubin, Eduardo Vilar-Sanchez, Ravaen Slay, Shweta Hegde, Genevieve Hartley, Spencer Lea, Coline Couillault, Madeline Steiner, Chun-Chieh Wang, Bhanu Venkatesulu, Cullen Taniguchi, Betty Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/167e52a6ae4147daa00f2698bdabe76d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/dbbc9e55372a4eb0b7ed5d6ea5f01369
Autor:
Rodney Cheng-En Hsieh, Sunil Krishnan, Ren-Chin Wu, Akash R. Boda, Arthur Liu, Michelle Winkler, Wen-Hao Hsu, Steven Hsesheng Lin, Mien-Chie Hung, Li-Chuan Chan, Krithikaa Rajkumar Bhanu, Anupallavi Srinivasamani, Ricardo Alexandre De Azevedo, Yung-Chih Chou, Ronald A. DePinho, Matthew Gubin, Eduardo Vilar, Chao Hsien Chen, Ravaen Slay, Priyamvada Jayaprakash, Shweta Mahendra Hegde, Genevieve Hartley, Spencer T. Lea, Rishika Prasad, Brittany Morrow, Coline Agnes Couillault, Madeline Steiner, Chun-Chieh Wang, Bhanu Prasad Venkatesulu, Cullen Taniguchi, Yon Son Betty Kim, Junjie Chen, Nils-Petter Rudqvist, Michael A. Curran
Publikováno v:
Sci Immunol
Radiotherapy (RT) of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)–expressing CRC cells systemically. However, abscopal tumor remissions are extremely rare, and the postirradiation immune escape mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bd40bd703e9b5a741446cde0e2b279
https://europepmc.org/articles/PMC9373855/
https://europepmc.org/articles/PMC9373855/
Autor:
Genevieve Hartley, Chao-Hsien Chen, Rodney Cheng-En Hsieh, Michael A. Curran, Spencer Thomas Lea
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundGlioblastoma is an aggressive primary brain malignancy that is characterized by a highly suppressive tumor microenvironment, including myeloid-derived suppressor cells, tumor-associated macrophages, and brain-resident microglia, but lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10a88b7b20211450ae45f57a3605486
https://doaj.org/article/dbbc9e55372a4eb0b7ed5d6ea5f01369
https://doaj.org/article/dbbc9e55372a4eb0b7ed5d6ea5f01369
Autor:
Genevieve Hartley, Leone S. Hopkins, Steven W. Dow, Amanda Guth, Brent Murphy, Robyn E. Elmslie
Publikováno v:
Veterinary and Comparative Oncology. 17:69-79
Cancer relapse following chemotherapy has been attributed in part to the presence of cancer stem cells (CSC), which drive tumor growth and metastasis and are highly resistant to the effects of cytotoxic chemotherapy. As a result, treatment with cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17051acec4c3c211e6b07c8bd1f11739
https://doi.org/10.1111/vco.12447
https://doi.org/10.1111/vco.12447
Publikováno v:
Cancer Immunology Research. 6:1260-1273
Tumor-associated macrophages (TAMs) express programmed cell death ligand 1 (PD-L1) and contribute to the immune-suppressive tumor microenvironment. Although the role of the PD-L1 and PD-1 interaction to regulate T-cell suppression is established, les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5486d7ec005067457ea8c2780f703046
https://doi.org/10.1158/2326-6066.cir-17-0537
https://doi.org/10.1158/2326-6066.cir-17-0537
Publikováno v:
Veterinary and Comparative Oncology. 16:352-360
Immunotherapies targeting checkpoint molecule programmed cell death 1 (PD-1) protein were shown to be effective for treatment of non-Hodgkin lymphoma in people, but little is known about the expression of PD-1 or its ligand PD-L1 by canine lymphoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d3cf8ca35055302b0f2c0c087781b6
https://doi.org/10.1111/vco.12386
https://doi.org/10.1111/vco.12386
Autor:
Ricardo De Azevedo, Ren-Chin Wu, Shweta M. Hegde, Michael A. Curran, Mien Chie Hung, Betty Y.S. Kim, Michelle Winkler, Genevieve Hartley, Krithikaa Rajkumar Bhanu, Li Chuan Chan, Chao-Hsien Chen, Anupallavi Srinivasamani, Sunil Krishnan, Madeline Steiner, Akash Boda, Eduardo Vilar-Sanchez, Ronald A. DePinho, Priyamvada Jayaprakash, Coline Agnes Couillault, Arthur Liu, Ravaen B Slay, Junjie Chen, Nils-Petter Rudqvist, Bhanu Venkatesulu, Spencer Thomas Lea, Brittany Morrow, Rishika Prasad, Cullen M. Taniguchi, Matthew M. Gubin, Rodney Cheng-En Hsieh, Yung-Chih Chou, Steven H. Lin, Wen Hao Hsu, Chun-Chieh Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundBackground: Radiotherapy of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)-expressing CRC cells systemically; however, incidences of abscopal tumor remission are extremely rare. We sought to unrav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b839a00836c6d618037dc783a7817e
https://doi.org/10.1136/jitc-2021-sitc2021.592
https://doi.org/10.1136/jitc-2021-sitc2021.592
Autor:
E. Faulhaber, Genevieve Hartley, Jonathan Coy, A. Caldwell, Amanda Guth, S. Dow, Daniel P. Regan, Jade N. Kurihara
Publikováno v:
Veterinary and Comparative Oncology. 15:534-549
Expression of programmed cell death receptor ligand 1 (PD-L1) on tumor cells has been associated with immune escape in human and murine cancers, but little is known regarding the immune regulation of PD-L1 expression by tumor cells and tumor-infiltra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553467eff4d845e645575e0bc976ac82
https://doi.org/10.1111/vco.12197
https://doi.org/10.1111/vco.12197
Autor:
Jayakumar Arumugam, Izabela Fokt, Michael A. Curran, Edward Felix, Rafal Zielinski, Waldemar Priebe, Genevieve Hartley, Midan Ai, Stanislaw Skora, Radj Venugopal, Krzysztof Grela
Publikováno v:
Cancer Research. 79:4799-4799
Introduction: Signal Transducer and Activators of Transcription 3 (STAT3) plays a pivotal role in carcinogenesis, chemo- and radio-sensitivity, metastasis and immune evasion in multiple malignances including Pancreatic Ductal Adenocarcinoma (PDAC). O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14fc52643860ca92dd1c1839dc46392f
https://doi.org/10.1158/1538-7445.am2019-4799
https://doi.org/10.1158/1538-7445.am2019-4799