Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Genevieve Escher"'
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Clarissa Vögel, Johann Kurz, Markus Mohaupt
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 16, Iss , Pp 100208- (2023)
Externí odkaz:
https://doaj.org/article/d1aed049148d4d9eb5bd9b8363484191
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Johann Kurz, Markus Mohaupt
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 16, Iss , Pp 100196- (2023)
Background: Different lines of evidence imply that metformin could alter steroid hormone homeostasis and thereby improve social impairment. Here, we tried to correlate the impact of metformin treatment on alterations in steroid hormones and autism sp
Externí odkaz:
https://doaj.org/article/975a7ed27ac14c77bba14a1da0e63ee3
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Hiten D. Mistry, Johann Kurz, Markus G. Mohaupt
Publikováno v:
Life, Vol 13, Iss 5, p 1094 (2023)
Background: We recently reported that metformin administration has substantial effects on steroid hormone concentrations. In this study, we specifically explored which enzymatic activities were affected before a first treatment versus after a time of
Externí odkaz:
https://doaj.org/article/ea6fc1b42df846899d05c80da21375f6
Autor:
Benedikt Gasser, Anca-Elena Calin, Genevieve Escher, Johann Kurz, Aglaia Emmenegger, Samuel Buerki, Arno Schmidt-Trucksäss, Markus Mohaupt
Publikováno v:
Life, Vol 12, Iss 11, p 1736 (2022)
Background: Metformin is an effective treatment option for type 2 diabetes mellitus, and it is, to this day, the most prescribed oral antiglycaemic drug. Besides its effects mainly on mitochondrial activity, an off-label use came up as a pharmaceutic
Externí odkaz:
https://doaj.org/article/979f09064f454d89acbfd49b988b165c
Publikováno v:
Life, Vol 12, Iss 7, p 1004 (2022)
Background: Evidence exists that steroid hormones are altered in individuals with autism, especially androgens. Despite lower prevalence in girls than boys, evidence of potential alterations in progesterone metabolites is sparse, so the aim of this s
Externí odkaz:
https://doaj.org/article/16cd5b959ec64b77bd18316ef53844e3
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Sterol 27-hydroxylase (CYP27A1) is a key enzyme in bile acids (BAs) biosynthesis and a regulator of cholesterol metabolism. Cyp27a1/Apolipoprotein E double knockout (DKO) mice fed with western diet (WD) are protected from atherosclerosis via up-regul
Externí odkaz:
https://doaj.org/article/b3d09f96d08e42cdb91f215b64741ae4
Autor:
Nigora Mukhamedova, Genevieve Escher, Wilissa D'Souza, Urbain Tchoua, Angela Grant, Zigmund Krozowski, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 11, Pp 2312-2322 (2008)
Eight proteins potentially involved in cholesterol efflux [ABCA1, ABCG1, CYP27A1, phospholipid transfer protein (PLTP), scavenger receptor type BI (SR-BI), caveolin-1, cholesteryl ester transfer protein, and apolipoprotein A-I (apoA-I)] were overexpr
Externí odkaz:
https://doaj.org/article/b7defb94d9b34a63ac7ab0a48c759345
Publikováno v:
Frontiers in Endocrinology
Sterol 27-hydroxylase (CYP27A1) is a key enzyme in bile acids (BAs) biosynthesis and a regulator of cholesterol metabolism. Cyp27a1/Apolipoprotein E double knockout (DKO) mice fed with western diet (WD) are protected from atherosclerosis via up-regul
Autor:
Monica Naomi Opiyo, Genevieve Escher, Christopher Kenyon, Jonathan Seckl, Ruth Andrew, Karen Chapman
Publikováno v:
Endocrine Abstracts.
Autor:
Rahel Klossner, Michael Groessl, Nadine Schumacher, Michaela Fux, Geneviève Escher, Sophia Verouti, Heidi Jamin, Bruno Vogt, Markus G. Mohaupt, Carine Gennari-Moser
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The steroid hormone progesterone accounts for immune tolerance in pregnancy. Enhanced progesterone metabolism to 6α-OH-pregnanolone occurs in complicated pregnancies such as in preeclampsia with preterm delivery or intrauterine growth restr
Externí odkaz:
https://doaj.org/article/75cad88b199f45d5bab5f61446be107f