Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Geneviève de Saint-Basile"'
Autor:
Amandine Crequer, Capucine Picard, Etienne Patin, Aurelia D'Amico, Avinash Abhyankar, Martine Munzer, Marianne Debré, Shen-Ying Zhang, Geneviève de Saint-Basile, Alain Fischer, Laurent Abel, Gérard Orth, Jean-Laurent Casanova, Emmanuelle Jouanguy
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44010 (2012)
Epidermodysplasia verruciformis (EV) is characterized by persistent cutaneous lesions caused by a specific group of related human papillomavirus genotypes (EV-HPVs) in otherwise healthy individuals. Autosomal recessive (AR) EVER1 and EVER2 deficienci
Externí odkaz:
https://doaj.org/article/23656b383e90483099f7796d22018221
Autor:
Meriem Belabed, François-Xavier Mauvais, Sophia Maschalidi, Mathieu Kurowska, Nicolas Goudin, Jian-Dong Huang, Alain Fischer, Geneviève de Saint Basile, Peter van Endert, Fernando E. Sepulveda, Gaël Ménasché
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Kinesin-1 is a motor protein transporting cargo along microtubules. Here the authors show that kinesin-1 is required for antigen cross-presentation and coordinates endosome scission from early endosomes to allow sorting internalized cargoes towards t
Externí odkaz:
https://doaj.org/article/6b390d25f10f4b0fa7554f33d2fe6480
Autor:
Claire Leveau, Tania Gajardo, Marie-Thérèse El-Daher, Nicolas Cagnard, Alain Fischer, Geneviève de Saint Basile, Fernando E. Sepulveda
Publikováno v:
Haematologica, Vol 105, Iss 1 (2020)
The molecular machinery that regulates the balance between self-renewal and differentiation properties of hematopoietic stem cells (HSC) has yet to be characterized in detail. Here we found that the tetratricopeptide repeat domain 7 A (Ttc7a) protein
Externí odkaz:
https://doaj.org/article/2bc8e9f8cac840b68e21d3a536395535
Autor:
Tayebeh Soheili, Amandine Durand, Fernando E. Sepulveda, Julie Rivière, Chantal Lagresle-Peyrou, Hanem Sadek, Geneviève de Saint Basile, Samia Martin, Fulvio Mavilio, Marina Cavazzana, Isabelle André-Schmutz
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2781-2789 (2017)
Abstract: Patients with mutations in the UNC13D gene (coding for Munc13-4 protein) suffer from familial hemophagocytic lymphohistiocytosis type 3 (FHL3), a life-threatening immune and hyperinflammatory disorder. The only curative treatment is allogen
Externí odkaz:
https://doaj.org/article/96f17802a96f484f96e5f9a61eee4791
Autor:
Cyril Longé, Manuela Bratti, Mathieu Kurowska, Shamila Vibhushan, Pierre David, Valère Desmeure, Jian-Dong Huang, Alain Fischer, Geneviève de Saint Basile, Fernando E. Sepulveda, Ulrich Blank, Gaël Ménasché
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:676-689
Mast cells (MCs) are key effectors of the allergic response. Following the cross-linking of IgE receptors (FcεRIs), they release crucial inflammatory mediators through degranulation. Although degranulation depends critically on secretory granule (SG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389839c1bb4f842b6b3bccdfd5ac2987
https://doi.org/10.1016/j.jaci.2022.04.009
https://doi.org/10.1016/j.jaci.2022.04.009
Autor:
Leishemba K. Thoidingjam, Cédric M. Blouin, Christine Gaillet, Aurélien Brion, Stéphanie Solier, Supaporn Niyomchon, Ahmed El Marjou, Sara Mouasni, Fernando E. Sepulveda, Geneviève de Saint Basile, Christophe Lamaze, Raphaël Rodriguez
Publikováno v:
Angewandte Chemie International Edition. 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe97696ee47c0a32545932d608e59f9c
https://doi.org/10.1002/anie.202208986
https://doi.org/10.1002/anie.202208986
Autor:
Leishemba K. Thoidingjam, Cédric M. Blouin, Christine Gaillet, Aurélien Brion, Stéphanie Solier, Supaporn Niyomchon, Ahmed El Marjou, Sara Mouasni, Fernando E. Sepulveda, Geneviève de Saint Basile, Christophe Lamaze, Raphaël Rodriguez
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e22531871037fe9b79c7dfbae1375d
https://doi.org/10.1002/ange.202208986
https://doi.org/10.1002/ange.202208986
Autor:
Leishemba K. Thoidingjam, Cédric M. Blouin, Christine Gaillet, Aurélien Brion, Stéphanie Solier, Supaporn Niyomchon, Ahmed El Marjou, Sara Mouasni, Fernando E. Sepulveda, Geneviève de Saint Basile, Christophe Lamaze, Raphaël Rodriguez
Publikováno v:
Angewandte Chemie International Edition
Interferons (IFN) are cytokines which, upon binding to cell surface receptors, trigger a series of downstream biochemical events including Janus Kinase (JAK) activation, phosphorylation of Signal Transducer and Activator of Transcription protein (STA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e524f3d2924ecd763450815b3a3f3fc1
https://pubmed.ncbi.nlm.nih.gov/35612562
https://pubmed.ncbi.nlm.nih.gov/35612562
Publikováno v:
Turkish Journal of Hematology, Vol 29, Iss 3, Pp 265-269 (2012)
Familial hemophagocytic lymphohistiocytosis (FHL) is a genetically heterogeneous disease. Presentation of the disease such as primarily fever, hepatosplenomegaly, and cytopenia, which are the results of functional degradation in cytotoxic T-lymphocyt
Externí odkaz:
https://doaj.org/article/1b369e04a0f841748215ff033647b64e
Autor:
Mathieu Kurowska, Gregoire Le Lay, Mathilde Bernard, Claire Leveau, Marie Lô, Despina Moshous, Gaël Ménasché, Pablo Vargas, Tania Gajardo, Marie-Thérèse El-Daher, Alain Fischer, Geneviève de Saint Basile, Bénédicte Neven, Fernando E. Sepulveda
The actin cytoskeleton has a crucial role in the maintenance of the immune homeostasis by controlling various cell processes, including cell migration. Mutations in the TTC7A gene have been described as the cause of a primary immunodeficiency associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52cb6b94c88cc27f9d183b73d6d56418
https://doi.org/10.1101/2021.10.14.464382
https://doi.org/10.1101/2021.10.14.464382
