Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Geneviève Paris"'
Autor:
Maneka Chitiprolu, Chantal Jagow, Veronique Tremblay, Emma Bondy-Chorney, Geneviève Paris, Alexandre Savard, Gareth Palidwor, Francesca A. Barry, Lorne Zinman, Julia Keith, Ekaterina Rogaeva, Janice Robertson, Mathieu Lavallée-Adam, John Woulfe, Jean-François Couture, Jocelyn Côté, Derrick Gibbings
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Many Amyotrophic Lateral Sclerosis (ALS)-linked mutations cause accumulation of stress granules, and most ALS cases are caused by repeat expansions in C9ORF72. Here the authors show that C9ORF72 and the autophagy receptor p62 interact to associate wi
Externí odkaz:
https://doaj.org/article/bbf18a982cd84beb955aa489eecafe37
Autor:
Alan Morettin, Geneviève Paris, Younes Bouzid, R. Mitchell Baldwin, Theresa J. Falls, John C. Bell, Jocelyn Côté
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Tudor domain containing protein 3 (TDRD3) is a modular protein identified based on its ability to recognize methylated arginine motifs through its Tudor domain. We have previously shown that TDRD3 localizes to cytoplasmic stress granules, a
Externí odkaz:
https://doaj.org/article/b3d5a9fb36324400b4cbf9271ff6ea12
Publikováno v:
ACS Omega, Vol 9, Iss 38, Pp 40204-40213 (2024)
Externí odkaz:
https://doaj.org/article/5d1f7415f33241ddb3da6159199a3a9d
Autor:
Olivier Binda, Franceline Juillard, Julia Novion Ducassou, Constance Kleijwegt, Geneviève Paris, Andréanne Didillon, Faouzi Baklouti, Armelle Corpet, Yohann Couté, Jocelyn Côté, Patrick Lomonte
Publikováno v:
Life Science Alliance. 6:e202201429
Although recent advances in gene therapy provide hope for spinal muscular atrophy (SMA) patients, the pathology remains the leading genetic cause of infant mortality. SMA is a monogenic pathology that originates from the loss of theSMN1gene in most c
Autor:
Emma Bondy-Chorney, Jocelyn Côté, Francesca A. Barry, Janice Robertson, Alexandre Savard, Julia Keith, Lorne Zinman, Véronique Tremblay, John Woulfe, Maneka Chitiprolu, Jean-François Couture, Mathieu Lavallée-Adam, Chantal Jagow, Gareth A. Palidwor, Ekaterina Rogaeva, Geneviève Paris, Derrick Gibbings
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Nature Communications
Nature Communications
Mutations in proteins like FUS which cause Amyotrophic Lateral Sclerosis (ALS) result in the aberrant formation of stress granules while ALS-linked mutations in other proteins impede elimination of stress granules. Repeat expansions in C9ORF72, the m
Autor:
John C. Bell, R. Mitchell Baldwin, Geneviève Paris, Alan Morettin, Theresa Falls, Jocelyn Côté, Younes Bouzid
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Tudor domain containing protein 3 (TDRD3) is a modular protein identified based on its ability to recognize methylated arginine motifs through its Tudor domain. We have previously shown that TDRD3 localizes to cytoplasmic stress granules, a structure
Publikováno v:
Canadian Journal of Science, Mathematics and Technology Education. 15:15-31
ResumePendant pres de deux ans, une communaute d’apprentissage, reunissant huit enseignantes ontariennes de 5e et 6e annee et une chercheuse, a ete formee dans le but d’ajuster les pratiques d’enseignement en sciences et technologie. Une etude
Troglitazone Induces Extracellular Matrix and Cytoskeleton Remodeling in Mouse Collecting Duct Cells
Autor:
Jaime Corinaldi, Geneviève Paris, Richard L. Hébert, Bernard J. Jasmin, Jordan Clark, Rania Nasrallah, Pedro Miura
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2012 (2012)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology
Peroxisome proliferator-activated receptor (PPARγ) has been shown to have a protective role in the nephron through its ability to inhibit a transforming growth factor- (TGF-β) mediated fibrotic response. In contrast, PPARγwas also shown to induce
Autor:
Rania Nasrallah, Jaime Corinaldi, Bernard J. Jasmin, Geneviève Paris, Pedro Miura, Richard L. Hébert, Jordan Clark
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1105-F1112
Peroxisome proliferator-activated receptor (PPAR)-γ is highly expressed in the collecting duct (CD), yet little is known about the effects of PPAR-γ ligands, thiazolidinediones (TZDs), on CD cell structure and function. M1 mouse cortical CD cells w
Autor:
Emma Bondy-Chorney, Andréanne Didillon, Gabriel Sanchez, Jocelyn Côté, Bernard J. Jasmin, Geneviève Paris, Janik Laframboise
Publikováno v:
Nucleic Acids Research
Loss of 'Survival of Motor Neurons' (SMN) leads to spinal muscular atrophy (SMA), a disease characterized by degeneration of spinal cord alpha motor neurons, resulting in muscle weakness, paralysis and death during early childhood. SMN is required fo