Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Geneviève Degols"'
Publikováno v:
Genes & Development. 12:1464-1473
Control of gene expression by stress-activated protein kinase (SAPK) cascades is crucial for combating cytotoxic stress. Elements of these cascades have been investigated in detail, but regulation of stress signal transduction from the cytoplasm to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f72e54f089ba614c847ef3a2f9899b37
https://doi.org/10.1101/gad.12.10.1464
https://doi.org/10.1101/gad.12.10.1464
Autor:
Geneviève Degols, Paul Russell
Publikováno v:
Molecular and Cellular Biology. 17:3356-3363
Exposure of mammalian cells to UV irradiation or alkylating agents leads to the activation of the c-Jun N-terminal kinase and p38 stress-activated protein kinase cascades, phosphorylation of c-Jun and ATF-2 bZIP transcription factors, and finally to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57a443ba672e90bb45709c6b1af468d
https://doi.org/10.1128/mcb.17.6.3356
https://doi.org/10.1128/mcb.17.6.3356
Publikováno v:
Journal of Biological Chemistry. 269:16933-16937
Triple helix formation of nucleic acids is the most rational approach to designing site-specific transcription inhibitors. To increase their efficiency, reactive moieties such as psoralen or ethenocytosine have been introduced on the third strand. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06a0825662d27d805b45d84007110bd7
https://doi.org/10.1016/s0021-9258(19)89479-6
https://doi.org/10.1016/s0021-9258(19)89479-6
Publikováno v:
Bioconjugate Chemistry. 5:8-13
Poly(L-lysine)-conjugated oligonucleotides complementary to the translation initiation region of the tat protein were tested for their capacity to inhibit HIV-1 replication in de novo infected cells. Sequence-specific antiviral effects were observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93863b6ee59a8de2a70e94963b6f040b
https://doi.org/10.1021/bc00025a002
https://doi.org/10.1021/bc00025a002
Publikováno v:
ChemInform. 25
Poly(L-lysine)-conjugated oligonucleotides complementary to the translation initiation region of the tat protein were tested for their capacity to inhibit HIV-1 replication in de novo infected cells. Sequence-specific antiviral effects were observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17db80de1f2505f2e723972f58ea298
https://doi.org/10.1002/chin.199425235
https://doi.org/10.1002/chin.199425235
Publikováno v:
Annals of the New York Academy of Sciences. 660:331-333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2ad7e2dab30a3f511bb86d09c4847f
https://doi.org/10.1111/j.1749-6632.1992.tb21104.x
https://doi.org/10.1111/j.1749-6632.1992.tb21104.x
Publikováno v:
Nucleosides and Nucleotides. 10:537-539
Antisense oligomers conjugated with various fluorochromes were microinjected in the cytoplasm of cultured cells, and their distribution was followed by microscopy. A fast translocation in the nuclei and a concentration on nuclear structures was obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01142c8b086eab7330a5709e8673bffa
https://doi.org/10.1080/07328319108046520
https://doi.org/10.1080/07328319108046520
Publikováno v:
Molecular and cellular biology. 16(6)
Spc1, an osmotic-stress-stimulated mitogen-activated protein kinase (MAPK) homolog in the fission yeast Schizosaccharomyces pombe, is required for the induction of mitosis and survival in high-osmolarity conditions. Spc1, also known as Sty1, is activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f2ed5a293f56ba8d640f15a6631e42
https://pubmed.ncbi.nlm.nih.gov/8649397
https://pubmed.ncbi.nlm.nih.gov/8649397
Autor:
Alain Pompon, Helen Loughrey, Olivier Zelphati, Jean-Louis Imbach, Gilles Gosselin, Annie-Françoise Maggio, Lee Leserman, Geneviève Degols, F. Puech
Publikováno v:
Antiviral research. 21(3)
Among the 2′,3′-dideoxynucleoside 5′-triphosphates containing a physiological base, 2′,3′-dideoxyuridine 5′-triphosphate (ddUTP) has been reported to be among the most powerful inhibitors of human immunodeficiency virus (HIV) reverse tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576cd7b970f4a8d4025256c9385b4915
https://pubmed.ncbi.nlm.nih.gov/8215297
https://pubmed.ncbi.nlm.nih.gov/8215297
Publikováno v:
Antisense research and development. 2(4)
Previously, we have reported that conjugation of antisense oligonucleotides to poly(L-lysine) (PLL) lowers their inhibitory concentration in several biological models. We have now tested these conjugates for inhibition of human immunodeficiency virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf27b6f649402902ae5878b315e9478
https://pubmed.ncbi.nlm.nih.gov/1284042
https://pubmed.ncbi.nlm.nih.gov/1284042