Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Geneviève Arseneault"'
Autor:
Guillaume Serwe, David Kachaner, Jessica Gagnon, Cédric Plutoni, Driss Lajoie, Eloïse Duramé, Malha Sahmi, Damien Garrido, Martin Lefrançois, Geneviève Arseneault, Marc K. Saba-El-Leil, Sylvain Meloche, Gregory Emery, Marc Therrien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Cell motility is a critical feature of invasive tumour cells that is governed by complex signal transduction events. Particularly, the underlying mechanisms that bridge extracellular stimuli to the molecular machinery driving motility remain
Externí odkaz:
https://doaj.org/article/8d40dfb655684ea5b52431fa626afc2e
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6939 (2009)
The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propaga
Externí odkaz:
https://doaj.org/article/9c7d1e3b56c9447e9e9f0cdc371a5660
Autor:
Lauriane Lecoq, Pascale Legault, Philippe R. Chabot, James G. Omichinski, Geneviève Arseneault, Normand Cyr, Luca Raiola
Publikováno v:
Nucleic Acids Research
p65 is a member of the NF-κB family of transcriptional regulatory proteins that functions as the activating component of the p65–p50 heterodimer. Through its acidic transactivation domain (TAD), p65 has the capacity to form interactions with sever
Autor:
Geneviève Arseneault, James G. Omichinski, Luca Raiola, Mathieu Lussier-Price, Jacques Archambault, Julien Lafrance-Vanasse, Xavier H. Mascle, David R. Gagnon, Pascale Legault
Publikováno v:
Structure. 21(11):2014-2024
SummaryLike other acidic transactivation domains (TAD), the minimal TAD from the erythroid-specific transcription factor EKLF (EKLFTAD) has been shown to contribute both to its transcriptional activity as well as to its ubiquitin(UBI)-mediated degrad
Autor:
Laurent Cappadocia, Pascale Legault, James G. Omichinski, Geneviève Arseneault, Julien Lafrance-Vanasse, Hung-Ta Chen
Publikováno v:
Nucleic Acids Research
The general transcription factor IIH (TFIIH) plays crucial roles in transcription as part of the pre-initiation complex (PIC) and in DNA repair as part of the nucleotide excision repair (NER) machinery. During NER, TFIIH recruits the 3′-endonucleas
Autor:
Geneviève Arseneault, Thomas Morse, Ivan de Paola, Mariarosaria De Simone, Annarita Del Gatto, Mathieu Lussier-Price, Laura Zaccaro, Chantal Langlois, Carlo Pedone, James G. Omichinski, Pascale Legault, Julien Lafrance-Vanasse
Publikováno v:
Journal of the American Chemical Society
134 (2012): 1715–1723.
info:cnr-pdr/source/autori:Langlois, C ; Del Gatto, A ; Arseneault, G ; Lafrance-Vanasse, J ; De Simone, M ; Morse, T 3 ; de Paola, I ; Lussier-Price, M ; Legault, P ; Pedone, C ; Zaccaro, L ; Omichinski, JG/titolo:Structure-Based Design of a Potent Artificial Transactivation Domain Based on p53/doi:/rivista:Journal of the American Chemical Society (Print)/anno:2012/pagina_da:1715/pagina_a:1723/intervallo_pagine:1715–1723/volume:134
134 (2012): 1715–1723.
info:cnr-pdr/source/autori:Langlois, C ; Del Gatto, A ; Arseneault, G ; Lafrance-Vanasse, J ; De Simone, M ; Morse, T 3 ; de Paola, I ; Lussier-Price, M ; Legault, P ; Pedone, C ; Zaccaro, L ; Omichinski, JG/titolo:Structure-Based Design of a Potent Artificial Transactivation Domain Based on p53/doi:/rivista:Journal of the American Chemical Society (Print)/anno:2012/pagina_da:1715/pagina_a:1723/intervallo_pagine:1715–1723/volume:134
Malfunctions in transcriptional regulation are associated with a number of critical human diseases. As a result, there is considerable interest in designing artificial transcription activators (ATAs) that specifically control genes linked to human di
Autor:
Shefali Soni, Mathieu Lussier-Price, Geneviève Arseneault, James J. Bieker, Paola Di Lello, Julien Lafrance-Vanasse, Thomas Morse, James G. Omichinski, Caroline Mas
Publikováno v:
Proceedings of the National Academy of Sciences. 108:10484-10489
Erythroid Krüppel-like factor (EKLF) plays an important role in erythroid development by stimulating β-globin gene expression. We have examined the details by which the minimal transactivation domain (TAD) of EKLF (EKLFTAD) interacts with several t
Publikováno v:
Annals of the New York Academy of Sciences. 1197:19-27
We present results showing that glucose signaling has proaging effects in the yeast Schizosaccharomyces pombe. Deletion of the receptor that senses extracellular glucose (Git3) increases the life span of S.pombe, while constitutive activation of the
Autor:
Laurent Cappadocia, Geneviève Arseneault, Pascale Legault, James G. Omichinski, Julien Lafrance-Vanasse
Publikováno v:
Nucleic Acids Research
XPC/Rad4 (human/yeast) recruits transcription faction IIH (TFIIH) to the nucleotide excision repair (NER) complex through interactions with its p62/Tfb1 and XPB/Ssl2 subunits. TFIIH then recruits XPG/Rad2 through interactions with similar subunits an
Autor:
Antoine E, Roux, Geneviève, Arseneault, Pascal, Chartrand, Gerardo, Ferbeyre, Luis A, Rokeach
Publikováno v:
Annals of the New York Academy of Sciences. 1197
We present results showing that glucose signaling has proaging effects in the yeast Schizosaccharomyces pombe. Deletion of the receptor that senses extracellular glucose (Git3) increases the life span of S. pombe, while constitutive activation of the