Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Geneva M. Omann"'
Autor:
Daniel Axelrod, Geneva M. Omann
Publikováno v:
Nature Reviews Molecular Cell Biology. 7:944-952
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b498aaad2a2b5d089891727e8856a1
https://doi.org/10.1038/nrm2062
https://doi.org/10.1038/nrm2062
Publikováno v:
Cellular Signalling. 18:1732-1747
It is well-established that the binding of N-formyl peptides to the N-formyl peptide receptor on neutrophils can be described by a kinetic scheme that involves two ligand-bound receptor states, both a low affinity ligand-receptor complex and a high a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf5eb2c4090580d7c4674c7b1ca9789
https://doi.org/10.1016/j.cellsig.2006.01.014
https://doi.org/10.1016/j.cellsig.2006.01.014
Autor:
Anuradha Rebbapragada, Geneva M. Omann, Alexis Traynor-Kaplan, Naveenraj L. Solomon, Michael L. Keil
Publikováno v:
Environmental Toxicology and Pharmacology. 19:313-322
The organochlorine insecticide lindane is a known activator of neutrophil responses. In this work we delineated the biochemical pathways by which lindane stimulates neutrophil oxidant production. Plasma membrane GTPase activity was not stimulated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ab3b7aa19dc7ecc6d3f724604a93be
https://doi.org/10.1016/j.etap.2004.08.008
https://doi.org/10.1016/j.etap.2004.08.008
Autor:
Tamara L. Kinzer-Ursem, Geneva M. Omann, John R. Traynor, Jennifer J. Linderman, Karyn L. Sutton, Afaf Absood, Anna Waller
Publikováno v:
Biochemistry. 43:8204-8216
The goal of this study was to elucidate the relationships between early ligand binding/receptor processing events and cellular responses for the N-formyl peptide receptor system on human neutrophils as a model of a GPCR system in a physiologically re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6ddd69f17b9ae3417859759315e6fd
https://doi.org/10.1021/bi035335i
https://doi.org/10.1021/bi035335i
Publikováno v:
Analytical Biochemistry. 325:175-184
A protocol for isolation of neutrophil plasma membranes utilizing a plasma membrane marker antibody, anti-CD15, attached to superparamagnetic beads was developed. Cells were initially disrupted by nitrogen cavitation and then incubated with anti-CD15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6061218c0c36723b8acf59f38deb31a7
https://doi.org/10.1016/j.ab.2003.10.039
https://doi.org/10.1016/j.ab.2003.10.039
Autor:
Jennifer J. Linderman, Peter S Chang, Algirdas J. Jesaitis, Naveenraj L. Solomon, Geneva M. Omann, Irfan J. Lodhi, Kimberley C Stone, Michael L. Keil
Publikováno v:
Biochemical and Biophysical Research Communications. 301:862-872
Subcellular fractionation of human neutrophils on linear sucrose density gradients was utilized to test the hypothesis that priming regulates the subcellular and sub-plasma membrane distribution of neutrophil G-protein subunits, G(ialpha2) and G(ialp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52faf334013f0577bc0ab3685e2fe95
https://doi.org/10.1016/s0006-291x(03)00057-3
https://doi.org/10.1016/s0006-291x(03)00057-3
Autor:
Geneva M. Omann, Dora R. Passino-Reader, Peter G. Meier, Jean V. Adams, Leonard I. Sweet, Gregory G. Miller
Publikováno v:
Fish & Shellfish Immunology. 13:11-26
The immunotoxicity of chemical combinations commonly encountered by the lake trout (Salvelinus namaycush) immune system was the focus of this study. It was hypothesised that combinations of an environmental contaminant (mercuric chloride or Aroclor 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512e4620ab0c9b9a2db0336d554b038e
https://doi.org/10.1006/fsim.2001.0381
https://doi.org/10.1006/fsim.2001.0381
Autor:
Russell E. Clift, Daniel B. Hinshaw, Geneva M. Omann, Irfan J. Lodhi, John F. Sweeney, Kathryn K. McMahon
Publikováno v:
Archives of Biochemistry and Biophysics. 387:66-77
The objective of this study was to understand factors responsible for apoptotic body formation and release during apoptosis. We have found that inhibition of mono-ADP ribosylation after ultraviolet (UV) light induction of apoptosis in HL-60 cells doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9458efec280638a69fca36f276d2ba4f
https://doi.org/10.1006/abbi.2000.2215
https://doi.org/10.1006/abbi.2000.2215
Publikováno v:
Cytometry. 45:102-114
Background: Fluorescently labeled ligands and flow cytometric methods allow quantification of receptor-ligand binding. Such methods require calibration of the fluorescence of bound ligands. Moreover, binding of unlabeled ligands can be calculated bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd0c62dee073dae86ddedda1a1d42d73
https://doi.org/10.1002/1097-0320(20011001)45:2<102::aid-cyto1152>3.0.co
https://doi.org/10.1002/1097-0320(20011001)45:2<102::aid-cyto1152>3.0.co
Autor:
Ramesh Rengan, Leonard I. Sweet, Laurence A. Boxer, Hans D. Ochs, Neil A. Lachant, Michael L. Keil, William T. Gunning, Geneva M. Omann
Publikováno v:
Blood. 95:1283-1292
Mutations in the Wiskott-Aldrich syndrome protein (WASP) have been hypothesized to cause defective actin cytoskeletal function. This resultant dysfunction of the actin cytoskeleton has been implicated in the pathogenesis of Wiskott-Aldrich syndrome (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ddb249bbffd25e2d99ffa57c0d048e2
https://doi.org/10.1182/blood.v95.4.1283.004k44_1283_1292
https://doi.org/10.1182/blood.v95.4.1283.004k44_1283_1292