Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Geneva Dickens"'
Autor:
Yasuhiro Katagiri, Hao Jiang, Kazuyo Takeda, Victor J. Ferrans, Alia Chabuk, Geneva Dickens, Gordon Guroff, Zu Xi Yu, Xu Wen Liu, Philip Lazarovici
Publikováno v:
Journal of Biological Chemistry. 274:26209-26216
The neurotrophins have been implicated in the acute regulation of synaptic plasticity. Neurotrophin-stimulated presynaptic calcium uptake appears to play a key role in this process. To understand the mechanism of neurotrophin-stimulated calcium uptak
Autor:
Hao Jiang, Vilen Movsesyan, Geneva Dickens, Philip Lazarovici, Yasuhiro Katagiri, Donald Fink, Mariam Monshipouri, Monika Fasler, Michael Whalin, Gordon Guroff, Peter I. Lelkes
Publikováno v:
Journal of Cellular Biochemistry. 66:229-244
Nerve growth factor (NGF) regulates proliferation, differentiation, and survival of sympathetic and sensory neurons through the tyrosine kinase activity of its receptor, p140trk. These biological effects of NGF depend upon the signal-mediating functi
Publikováno v:
Journal of Neuroscience Research. 40:494-498
K-252a treatment produced a 30–50% increase in the uptake of radioactive calcium by PC12 cells within 3–4 minutes. The increase in uptake was partially blocked by inhibitors of voltage-operated calcium channels, such as nifedipine, but not by inh
Autor:
Alia Chabuk, Danielle St. Ulme, Philip Lazarovici, Gordon Guroff, Geneva Dickens, Miriam Lavarreda, Hao Jiang
Publikováno v:
The Journal of biological chemistry. 272(11)
Human p140(trk) and p75(NGFR) were transfected separately into 3T3 cells. Nerve growth factor stimulates calcium uptake into both transfectants but not into untransfected 3T3 cells. p140(trk) cells were stimulated maximally by 25 ng/ml; 100 ng/ml was
Publikováno v:
Journal of neuroscience research. 47(3)
Both nerve growth factor (NGF) and K-252a stimulate the uptake of calcium into PC12 cells. Stimulation by either is prevented by pretreatment of the cells with the tumor promoter phorbol 12-myristate 13-acetate (PMA), suggesting an involvement of pro
Autor:
Gordon Guroff, Geneva Dickens
Publikováno v:
Journal of Neurochemistry. 40:1271-1277
Nerve growth factor treatment produces a large increase in the activity of ornithine decarboxylase and a moderate decrease in the activity of S-adenosylmethionine decarboxylase in PC12 cells. These changes are reflected weakly, if at all, in the leve
Publikováno v:
Biochemical and Biophysical Research Communications. 114:1189-1193
Treatment of PC12 cells with fibroblast growth factor(s) from either brain or pituitary caused neurite outgrowth comparable to that produced by nerve growth factor. The neurite outgrowth was preceded by a substantial rise in the activity of ornithine
Publikováno v:
Journal of Biological Chemistry. 250:6672-6678
Phenylalanine hydroxylase from Pseudomonas sp. (ATCC 11299a) has been purified 25- to 30-fold by a procedure which has been modified from that previously described for this organism (Guroff, G., and Ito, T. (1965) J. Biol. Chem. 240, 1175-1184; Gurof
Publikováno v:
Journal of Biological Chemistry. 249:7186-7191
A tryptophan hydroxylase has been purified approximately 20-fold from Chromobacterium violaceum. The enzyme is inducible and it is induced to a greater extent by phenylalanine than by tryptophan. The hydroxylation requires molecular oxygen and a redu
Publikováno v:
Journal of Neurochemistry. 37:342-349
Both nerve growth factor and epidermal growth factor cause an induction of ornithine decarboxylase in the rat pheochromocytoma clone PC12. The induction by nerve growth factor is transcription-dependent and occurs within 4 to 6 h. Antibody studies in