Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Genetics and Genomics/Microbial Evolution and Genomics"'
Autor:
Jeffrey T. Foster, Sharon J. Peacock, Talima Pearson, Apichai Tuanyok, David M. Wagner, Amy J. Vogler, Heidie Hornstra, Rebecca E. Colman, Erin P. Price, Derek S. Sarovich, Paul Keim, Benjamin Leadem, Jennifer L. Ginther, Tamara L. Max, Direk Limmathurotsakul, Julia Dale
Publikováno v:
PLoS Pathogens, Vol 6, Iss 1, p e1000725 (2010)
PLoS Pathogens
PLoS Pathogens
Little is currently known about bacterial pathogen evolution and adaptation within the host during acute infection. Previous studies of Burkholderia pseudomallei, the etiologic agent of melioidosis, have shown that this opportunistic pathogen mutates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deec7a9fac21e7c77a7499815808b782
https://ora.ox.ac.uk/objects/uuid:5aa6b5ea-3d20-4927-98d3-7046aaa2a66d
https://ora.ox.ac.uk/objects/uuid:5aa6b5ea-3d20-4927-98d3-7046aaa2a66d
Autor:
Paolo S. Ocampo, George J. Armelagos, Nigel J. Saunders, Kristin N. Harper, Michael S. Silverman, Allan Pillay, Robert W. George, Shelly Bolotin, Bret Steiner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 1, p e148 (2008)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Since the first recorded epidemic of syphilis in 1495, controversy has surrounded the origins of the bacterium Treponema pallidum subsp. pallidum and its relationship to the pathogens responsible for the other treponemal diseases: yaws, en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77896c34db80cd51fc98b669c0004d45
https://doi.org/10.1371/journal.pntd.0000148
https://doi.org/10.1371/journal.pntd.0000148
Microevolution of Helicobacter pylori during prolonged infection of single hosts and within families
Autor:
Morelli, G., Didelot, X., Kusecek, B., Schwarz, S., Bahlawane, C., Falush, D., Suerbaum, S., Achtman, M.
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001036 (2010)
PLoS Genetics
PLoS Genetics
Our understanding of basic evolutionary processes in bacteria is still very limited. For example, multiple recent dating estimates are based on a universal inter-species molecular clock rate, but that rate was calibrated using estimates of geological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d37d497423042fd2300799f89671a319
https://ora.ox.ac.uk/objects/uuid:029bbd62-7c7a-4f99-8a89-7fc1d2decc43
https://ora.ox.ac.uk/objects/uuid:029bbd62-7c7a-4f99-8a89-7fc1d2decc43
Publikováno v:
PLoS Biology
PLoS Biology, Vol 9, Iss 6, p e1000622 (2011)
PLoS Biology, Vol 9, Iss 6, p e1000622 (2011)
The authors propose that short repeat sequences may play an important role in causing the pervasive clustering of mutations across diverse genomes from prokaryotes to humans.
The genome-sequencing gold rush has facilitated the use of comparative
The genome-sequencing gold rush has facilitated the use of comparative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e1c515d45ed64cadb4348060adccdb
http://europepmc.org/articles/PMC3114760
http://europepmc.org/articles/PMC3114760
Autor:
Michael Lynch
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1001389 (2011)
PLoS Genetics
PLoS Genetics
In a series of publications, I and my colleagues have developed hypotheses for how the evolution of various aspects of genome architecture is expected to proceed under conditions in which the forces of random genetic drift and mutation predominate (e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47860743bfefad03dd4dfa1c2524a5d
http://europepmc.org/articles/PMC3111481?pdf=render
http://europepmc.org/articles/PMC3111481?pdf=render
Autor:
Daniel L. Hartl, Daria Van Tyne, Elaine Angelino, Kayla G. Barnes, Nicholas A. Furlotte, Bruce W. Birren, David M. B. Rosen, Dyann F. Wirth, Souleymane Mboup, Daniel L. K. Yamins, Ilya Shlyakhter, Charles A. Johnson, Rachel F. Daniels, Sarah K. Volkman, Joseph F. Cortese, Eleazar Eskin, Justin S. Becker, Sharon R. Grossman, Christian T. Happi, Elinor K. Karlsson, Daniel E. Neafsey, Daouda Ndiaye, Pardis C. Sabeti, Ousmane Sarr, Hyun Min Kang, Danny A. Milner, Eric S. Lander, Stephen F. Schaffner, Amanda K. Lukens, Daniel J. Park, Roger C. Wiegand
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001383 (2011)
PLoS Genetics
PLoS genetics, vol 7, iss 4
PLoS
PLoS Genetics
PLoS genetics, vol 7, iss 4
PLoS
The Plasmodium falciparum parasite's ability to adapt to environmental pressures, such as the human immune system and antimalarial drugs, makes malaria an enduring burden to public health. Understanding the genetic basis of these adaptations is criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94d801a32f09b3c69ef6ecacbc5c0d5
http://europepmc.org/articles/PMC3080868?pdf=render
http://europepmc.org/articles/PMC3080868?pdf=render
Autor:
John van der Oost, Eynat Dellus, Florien A. Gorter, J. Arjan G. M. de Visser, Alfons J. M. Debets, Dan S. Tawfik, Rolf F. Hoekstra, Merijn L. M. Salverda
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001321 (2011)
Plos Genetics 7 (2011) 3
Plos Genetics, 7(3)
PLoS Genetics
Plos Genetics 7 (2011) 3
Plos Genetics, 7(3)
PLoS Genetics
Whether evolution is erratic due to random historical details, or is repeatedly directed along similar paths by certain constraints, remains unclear. Epistasis (i.e. non-additive interaction between mutations that affect fitness) is a mechanism that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75af2ed17066b97bfa770d6c9dec8c18
http://europepmc.org/articles/PMC3048372?pdf=render
http://europepmc.org/articles/PMC3048372?pdf=render
Viral genome segmentation can result from a trade-off between genetic content and particle stability
Autor:
Celia Perales, Juan García-Arriaza, Esteban Domingo, Samuel Ojosnegros, Cristina Escarmís, Mauricio G. Mateu, Armando Arias, Susanna C. Manrubia
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001344 (2011)
PLoS Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
The evolutionary benefit of viral genome segmentation is a classical, yet unsolved question in evolutionary biology and RNA genetics. Theoretical studies anticipated that replication of shorter RNA segments could provide a replicative advantage over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63715b2cd98b0c0db3f8ed0f670e20ee
http://europepmc.org/articles/PMC3060069?pdf=render
http://europepmc.org/articles/PMC3060069?pdf=render
Autor:
Isak S. Pretorius, Angus H. Forgan, Anthony R. Borneman, Brian Desany, Michael Egholm, David W. H. Riches, Jason P. Affourtit, Paul J. Chambers
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001287 (2011)
PLoS Genetics
PLoS Genetics
Human intervention has subjected the yeast Saccharomyces cerevisiae to multiple rounds of independent domestication and thousands of generations of artificial selection. As a result, this species comprises a genetically diverse collection of natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d0ae4290a150fa1bd176f514a2437a
http://europepmc.org/articles/PMC3033381?pdf=render
http://europepmc.org/articles/PMC3033381?pdf=render
Autor:
Gerald W. Tannock, Prabhu B. Patil, Andrew K. Benson, Jens Walter, Hope Tice, Nicholas C. K. Heng, Phaik Lyn Oh, Eileen Dalin, Donald A. MacKenzie, Min Zhang, Loren Hauser, Jaehyoung Kim, Diane M. Loach, Bruce M. Pearson, Alla Lapidus, Steven A. Frese, Natalia Ivanova, Eugene Goltsman, Miriam Land, Nikos C. Kyrpides, Nathalie Juge
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001314 (2011)
PLoS Genetics
PLoS Genetics
Recent research has provided mechanistic insight into the important contributions of the gut microbiota to vertebrate biology, but questions remain about the evolutionary processes that have shaped this symbiosis. In the present study, we showed in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428d4dfa44d6d9d16a34121b9ab3193c
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21379339/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21379339/pdf/?tool=EBI